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5Y2Z

Crystal structure of human LGI1 EPTP-ADAM22 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...
(A, C, E, G, I...)
Disintegrin and metalloproteinase domain-containing protein 22polymer50455761.36UniProt (Q9P0K1)
Pfam (PF01421)
Pfam (PF00200)
Pfam (PF08516)
Pfam (PF07974)
Homo sapiens (Human)ADAM 22,Metalloproteinase-disintegrin ADAM22-3,Metalloproteinase-like,disintegrin-like,and cysteine-rich protein 2
2G, H, I, J, K...
(B, D, F, H, J...)
Leucine-rich glioma-inactivated protein 1polymer34740378.56UniProt (O95970)
Pfam (PF03736)
Homo sapiens (Human)Epitempin-1
3M, O, Q, T
(M, O, Q, T)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.44In PDB
GlyTouCan (G42666HT)
4N, S
(N, S)
beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched732.72In PDB
GlyTouCan (G32152BH)
5P, U, V
(P, U, V)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranosebranched570.53In PDB
GlyTouCan (G21290RB)
6R
(R)
alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched367.31In PDB
GlyTouCan (G86851RC)
7AA, BA, CA, DA, EA...
(C, E, G, I, K...)
CALCIUM IONnon-polymer40.124Chemie (CA)
8SA, VA
(H, L)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
9AB, BB, CB, DB, EB...
(I, K, B, D, F...)
waterwater18.0914Chemie (HOH)
Sequence modifications
A, C, E, G, I, K: 233 - 729 (UniProt: Q9P0K1)
PDBExternal DatabaseDetails
Lys 730-expression tag
His 731-expression tag
His 732-expression tag
His 733-expression tag
His 734-expression tag
His 735-expression tag
His 736-expression tag
B, D, F, H, J, L: 224 - 557 (UniProt: O95970)
PDBExternal DatabaseDetails
Asp 218-expression tag
Ala 219-expression tag
Ala 220-expression tag
Gln 221-expression tag
Pro 222-expression tag
Ala 223-expression tag
Lys 558-expression tag
His 559-expression tag
His 560-expression tag
His 561-expression tag
His 562-expression tag
His 563-expression tag
His 564-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains12
Total formula weight576838.8
BranchedNumber of molecules10
Total formula weight5241.9
Non-Polymers*Number of molecules26
Total formula weight1404.3
All*Total formula weight583485.1
*Water molecules are not included.

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PDB entries from 2024-11-06

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