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6YLL

Biochemical, Cellular and Structural Characterization of Novel ERK3 Inhibitors

Summary for 6YLL
Entry DOI10.2210/pdb6yll/pdb
DescriptorMitogen-activated protein kinase 6, ~{N}4-[3-(4-methoxyphenyl)-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl]cyclohexane-1,4-diamine (3 entities in total)
Functional Keywordshuman mitogen activated protein kinase 6 (mapk6), erk3, inhibitor, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total formula weight72726.74
Authors
Graedler, U. (deposition date: 2020-04-07, release date: 2020-09-23, Last modification date: 2024-01-24)
Primary citationGradler, U.,Busch, M.,Leuthner, B.,Raba, M.,Burgdorf, L.,Lehmann, M.,Linde, N.,Esdar, C.
Biochemical, cellular and structural characterization of novel and selective ERK3 inhibitors.
Bioorg.Med.Chem.Lett., 30:127551-127551, 2020
Cited by
PubMed: 32927028
DOI: 10.1016/j.bmcl.2020.127551
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.89 Å)
Structure validation

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