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4RL2
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BU of 4rl2 by Molmil
Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Descriptor: (1R)-2-({(R)-carboxy[(2R,5S)-4-carboxy-5-methyl-5,6-dihydro-2H-1,3-thiazin-2-yl]methyl}amino)-2-oxo-1-phenylethanaminium, Beta-lactamase NDM-1, ZINC ION
Authors:Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
Deposit date:2014-10-15
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.008 Å)
Cite:Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
4RM5
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BU of 4rm5 by Molmil
Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Descriptor: Beta-lactamase NDM-1, ZINC ION
Authors:Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
Deposit date:2014-10-19
Release date:2014-11-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
4RL0
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BU of 4rl0 by Molmil
Structural and mechanistic insights into NDM-1 catalyzed hydrolysis of cephalosporins
Descriptor: (2R,5S)-5-[(carbamoyloxy)methyl]-2-[(R)-carboxy{[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetyl]amino}methyl]-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Beta-lactamase NDM-1, ZINC ION
Authors:Feng, H, Ding, J, Zhu, D, Liu, X, Xu, X, Zhang, Y, Zang, S, Wang, D.-C, Liu, W.
Deposit date:2014-10-14
Release date:2014-11-19
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins.
J.Am.Chem.Soc., 136, 2014
1YYX
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BU of 1yyx by Molmil
The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) at 2.8M urea
Descriptor: Redesigned apo-cytochrome b562
Authors:Feng, H, Vu, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-25
Release date:2005-08-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Detection and structure determination of an equilibrium unfolding intermediates of Rd-apocytochrome b562: native fold with non-native hydrophobic interactions
J.Mol.Biol., 343, 2004
1YZA
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BU of 1yza by Molmil
The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) with the N-terminal helix unfolded
Descriptor: Redesigned apo-cytochrome b562
Authors:Feng, H, Takei, T, Lipsitz, R, Tjandra, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-28
Release date:2005-08-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Specific non-native hydrophobic interactions in a hidden folding intermediate: implication for protein folding
Biochemistry, 42, 2003
1YYJ
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BU of 1yyj by Molmil
The NMR solution structure of a redesigned apocytochrome b562:Rd-apocyt b562
Descriptor: redesigned apocytochrome B562
Authors:Feng, H, Takei, J, Lipsitz, R, Tjandra, N, Bai, Y, Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-25
Release date:2005-08-25
Last modified:2023-09-27
Method:SOLUTION NMR
Cite:Specific non-native hydrophobic interactions in a hidden folding intermediate: implications for protein folding
Biochemistry, 42, 2003
1YZC
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BU of 1yzc by Molmil
The solution structure of a redesigned apocytochrome B562 (Rd-apocyt b562) with the N- and a part of the C-terminal helices unfolded
Descriptor: edesigned apo-cytochrome b562
Authors:Feng, H, Zhou, Z, Bai, Y, Berkeley Structural Genomics Center (BSGC)
Deposit date:2005-02-28
Release date:2006-03-28
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:A protein folding pathway with multiple folding intermediates at atomic resolution
Proc.Natl.Acad.Sci.Usa, 102, 2005
5HDK
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BU of 5hdk by Molmil
Crystal structure of heat shock factor 2-DBD
Descriptor: CHLORIDE ION, Heat shock factor protein 2, POTASSIUM ION, ...
Authors:Feng, H, Liu, W, Wang, D.C.
Deposit date:2016-01-05
Release date:2017-01-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:HSF1-DBD crystal structure
To Be Published
5HDN
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BU of 5hdn by Molmil
Crystal structure of heat shock factor1-DBD complex with ds-DNA and TtT
Descriptor: CITRIC ACID, DNA (5'-D(*GP*GP*TP*TP*CP*TP*AP*GP*AP*AP*CP*C)-3'), Heat shock factor protein 1, ...
Authors:Feng, H, Liu, W, Wang, D.C.
Deposit date:2016-01-05
Release date:2017-01-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.68 Å)
Cite:HSF1-DBD crystal structure
To Be Published
5HDG
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BU of 5hdg by Molmil
crystal structure of heat shock factor 1-DBD
Descriptor: Heat shock factor protein 1, SODIUM ION
Authors:Feng, H, Liu, W, Wang, D.C.
Deposit date:2016-01-05
Release date:2017-01-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:HSF1-DBD crystal structure
To Be Published
5YPI
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BU of 5ypi by Molmil
Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EI1 complex
Descriptor: (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole -5-carboxylic acid, CHLORIDE ION, GLYCEROL, ...
Authors:Feng, H, Wang, D, Liu, W.
Deposit date:2017-11-01
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPK
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BU of 5ypk by Molmil
Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EI2 complex
Descriptor: (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, CHLORIDE ION, Metallo-beta-lactamase NDM-1, ...
Authors:Feng, H, Wang, D, Liu, W.
Deposit date:2017-11-02
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPN
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BU of 5ypn by Molmil
Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI2 complex
Descriptor: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoy l)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Metallo-beta-lactamase NDM-1, SULFATE ION, ...
Authors:Feng, H, Liu, W, Wang, D.
Deposit date:2017-11-02
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPL
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BU of 5ypl by Molmil
Crystal structure of NDM-1 bound to hydrolyzed imipenem representing an EP complex
Descriptor: (2R,4S)-2-[(1S,2R)-1-carboxy-2-hydroxypropyl]-4-[(2-{[(Z)-iminomethyl]amino}ethyl)sulfanyl]-3,4-dihydro-2H-pyrrole-5-ca rboxylic acid, CHLORIDE ION, Metallo-beta-lactamase NDM-1, ...
Authors:Feng, H, Wang, D, Liu, W.
Deposit date:2017-11-02
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
5YPM
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BU of 5ypm by Molmil
Crystal structure of NDM-1 bound to hydrolyzed meropenem representing an EI1 complex
Descriptor: (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid, Metallo-beta-lactamase NDM-1, SULFATE ION, ...
Authors:Feng, H, Wang, D, Liu, W.
Deposit date:2017-11-02
Release date:2018-02-21
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:The mechanism of NDM-1-catalyzed carbapenem hydrolysis is distinct from that of penicillin or cephalosporin hydrolysis.
Nat Commun, 8, 2017
7BYF
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BU of 7byf by Molmil
The crystal structure of mouse ORF10-Rae1-Nup98 complex
Descriptor: 10 protein, MERCURY (II) ION, Peptidase S59 domain-containing protein, ...
Authors:Gao, P, Feng, H.
Deposit date:2020-04-22
Release date:2021-03-24
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism underlying selective inhibition of mRNA nuclear export by herpesvirus protein ORF10.
Proc.Natl.Acad.Sci.USA, 117, 2020
2K8F
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BU of 2k8f by Molmil
Structural Basis for the Regulation of p53 Function by p300
Descriptor: Cellular tumor antigen p53, Histone acetyltransferase p300
Authors:Bai, Y, Feng, H, Jenkins, L.M, Durell, S.R, Wiodawer, A, Appella, E.
Deposit date:2008-09-08
Release date:2009-03-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structural Basis for p300 Taz2-p53 TAD1 Binding and Modulation by Phosphorylation.
Structure, 17, 2009
2AXL
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BU of 2axl by Molmil
Solution structure of a multifunctional DNA- and protein-binding domain of human Werner syndrome protein
Descriptor: Werner syndrome
Authors:Hu, J.-S, Feng, H, Zeng, W, Lin, G.-X, Xi, X.G.
Deposit date:2005-09-05
Release date:2005-12-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of a multifunctional DNA- and protein-binding motif of human Werner syndrome protein.
Proc.Natl.Acad.Sci.Usa, 102, 2005
2RPI
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BU of 2rpi by Molmil
The NMR structure of the submillisecond folding intermediate of the Thermus thermophilus ribonuclease H
Descriptor: Ribonuclease H
Authors:Zhou, Z, Feng, H, Bai, Y.
Deposit date:2008-05-16
Release date:2009-03-31
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:The high-resolution NMR structure of the early folding intermediate of the Thermus thermophilus ribonuclease H
J.Mol.Biol., 384, 2008
2JSS
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BU of 2jss by Molmil
NMR structure of chaperone Chz1 complexed with histone H2A.Z-H2B
Descriptor: Chimera of Histone H2B.1 and Histone H2A.Z, Uncharacterized protein YER030W
Authors:Zhou, Z, Feng, H, Hansen, D.F, Kato, H, Luk, E, Freedberg, D.I, Kay, L.E, Wu, C, Bai, Y.
Deposit date:2007-07-11
Release date:2008-05-20
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:NMR structure of chaperone Chz1 complexed with histones H2A.Z-H2B.
Nat.Struct.Mol.Biol., 15, 2008
8K4B
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BU of 8k4b by Molmil
Cryo-EM structure of nucleotide-bound ComA with ZinC ion
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Competence factor transporting ATP-binding protein/permease ComA, ZINC ION
Authors:Yu, L, Xin, X, Min, L, Feng, H.
Deposit date:2023-07-17
Release date:2023-10-11
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis of peptide secretion for Quorum sensing by ComA.
Nat Commun, 14, 2023
2L5A
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BU of 2l5a by Molmil
Structural basis for recognition of centromere specific histone H3 variant by nonhistone Scm3
Descriptor: Histone H3-like centromeric protein CSE4, Protein SCM3, Histone H4
Authors:Zhou, Z, Feng, H, Zhou, B, Ghirlando, R, Hu, K, Zwolak, A, Jenkins, L, Xiao, H, Tjandra, N, Wu, C, Bai, Y.
Deposit date:2010-10-28
Release date:2011-03-16
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural basis for recognition of centromere histone variant CenH3 by the chaperone Scm3.
Nature, 472, 2011
7YVC
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BU of 7yvc by Molmil
Aplysia californica FaNaC in apo state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
Deposit date:2022-08-19
Release date:2023-08-09
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023
7YVB
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BU of 7yvb by Molmil
Aplysia californica FaNaC in ligand bound state
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FMRFamide-gated Na+ channel, ...
Authors:Chen, Q.F, Liu, F.L, Dang, Y, Feng, H, Zhang, Z, Ye, S.
Deposit date:2022-08-19
Release date:2023-08-09
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structure and mechanism of a neuropeptide-activated channel in the ENaC/DEG superfamily.
Nat.Chem.Biol., 19, 2023
2LY8
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BU of 2ly8 by Molmil
The budding yeast chaperone Scm3 recognizes the partially unfolded dimer of the centromere-specific Cse4/H4 histone variant
Descriptor: Budding yeast chaperone Scm3
Authors:Hong, J, Feng, H, Zhou, Z, Ghirlando, R, Bai, Y.
Deposit date:2012-09-13
Release date:2012-12-12
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Identification of Functionally Conserved Regions in the Structure of the Chaperone/CenH3/H4 Complex.
J.Mol.Biol., 425, 2013

 

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數據於2024-10-30公開中

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