8WNH
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![BU of 8wnh by Molmil](/molmil-images/mine/8wnh) | |
7DL9
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![BU of 7dl9 by Molmil](/molmil-images/mine/7dl9) | Crystal structure of nucleoside transporter NupG | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, Nucleoside permease NupG | Authors: | Wang, C, Xiao, Q.J, Deng, D. | Deposit date: | 2020-11-26 | Release date: | 2021-04-07 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Molecular basis for substrate recognition by the bacterial nucleoside transporter NupG. J.Biol.Chem., 296, 2021
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7WNH
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![BU of 7wnh by Molmil](/molmil-images/mine/7wnh) | Crystal structure of Nurr1 binding to NBRE | Descriptor: | DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), Nuclear receptor subfamily 4 group A member 2, ... | Authors: | Zhao, M, Xu, T, Wang, N, Guo, Y, Liu, J. | Deposit date: | 2022-01-18 | Release date: | 2023-01-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXR alpha heterodimer. Proc.Natl.Acad.Sci.USA, 119, 2022
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2H2Z
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![BU of 2h2z by Molmil](/molmil-images/mine/2h2z) | Crystal structure of SARS-CoV main protease with authentic N and C-termini | Descriptor: | Replicase polyprotein 1ab | Authors: | Yang, H, Xue, X, Shen, W, Zhao, Q, Rao, Z. | Deposit date: | 2006-05-20 | Release date: | 2007-04-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Production of authentic SARS-CoV M(pro) with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction J.Mol.Biol., 366, 2007
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3LO2
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![BU of 3lo2 by Molmil](/molmil-images/mine/3lo2) | |
2KJD
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![BU of 2kjd by Molmil](/molmil-images/mine/2kjd) | |
5FHZ
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![BU of 5fhz by Molmil](/molmil-images/mine/5fhz) | |
4PHS
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![BU of 4phs by Molmil](/molmil-images/mine/4phs) | |
7UDH
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![BU of 7udh by Molmil](/molmil-images/mine/7udh) | Integrin alaphIIBbeta3 complex with BMS4-3 | Descriptor: | (4-{[(5S)-3-(piperidin-4-yl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-19 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.99998844 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UK9
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![BU of 7uk9 by Molmil](/molmil-images/mine/7uk9) | Integrin alaphIIBbeta3 complex with lamifiban (Mn) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-31 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.60001969 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UFH
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![BU of 7ufh by Molmil](/molmil-images/mine/7ufh) | Integrin alaphIIBbeta3 complex with fradafiban (Mn/Ca) | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-22 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.99768162 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UKT
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![BU of 7ukt by Molmil](/molmil-images/mine/7ukt) | Integrin alaphIIBbeta3 complex with BMS4.2 | Descriptor: | (1-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperidin-4-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-04-01 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.36994433 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UCY
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![BU of 7ucy by Molmil](/molmil-images/mine/7ucy) | Integrin alaphIIBbeta3 complex with gantofiban | Descriptor: | (4-{[(5R)-3-(4-carbamimidoylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 Fab light chain, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-17 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.34996319 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7UJK
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![BU of 7ujk by Molmil](/molmil-images/mine/7ujk) | Integrin alaphIIBbeta3 complex with lamifiban | Descriptor: | 10E5 Fab heavy chain, 10E5 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lin, F.-Y, Zhu, J, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-30 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.43265581 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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7U9V
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![BU of 7u9v by Molmil](/molmil-images/mine/7u9v) | Integrin alaphIIBbeta3 complex with BMS4-1 | Descriptor: | (4-{[(5S)-3-(4-carbamimidoylphenyl)-4,5-dihydro-1,2-oxazol-5-yl]methyl}piperazin-1-yl)acetic acid, 10E5 Fab heavy chain, 10E5 light chain, ... | Authors: | Zhu, J, Lin, F.-Y, Zhu, J, Springer, T.A. | Deposit date: | 2022-03-11 | Release date: | 2022-08-17 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.25492167 Å) | Cite: | A general chemical principle for creating closure-stabilizing integrin inhibitors. Cell, 185, 2022
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2KFU
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![BU of 2kfu by Molmil](/molmil-images/mine/2kfu) | PknB-phosphorylated Rv1827 | Descriptor: | Rv1827 pThr 22 | Authors: | Smerdon, S.J, Nott, T.J, Kelly, G. | Deposit date: | 2009-02-27 | Release date: | 2009-06-16 | Last modified: | 2021-10-20 | Method: | SOLUTION NMR | Cite: | An intramolecular switch regulates phosphoindependent FHA domain interactions in Mycobacterium tuberculosis. Sci.Signal., 2, 2009
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3LO1
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![BU of 3lo1 by Molmil](/molmil-images/mine/3lo1) | |
3LOE
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![BU of 3loe by Molmil](/molmil-images/mine/3loe) | |
3LO6
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![BU of 3lo6 by Molmil](/molmil-images/mine/3lo6) | |
3LO4
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![BU of 3lo4 by Molmil](/molmil-images/mine/3lo4) | |
3LO9
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![BU of 3lo9 by Molmil](/molmil-images/mine/3lo9) | |
7DMP
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![BU of 7dmp by Molmil](/molmil-images/mine/7dmp) | Mouse radial spoke complex | Descriptor: | Radial spoke head 1 homolog, Radial spoke head protein 4 homolog A, Radial spoke head protein 9 homolog | Authors: | Zheng, W, Cong, Y. | Deposit date: | 2020-12-05 | Release date: | 2021-07-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM Proc.Natl.Acad.Sci.USA, 118, 2021
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4M5C
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![BU of 4m5c by Molmil](/molmil-images/mine/4m5c) | Crystal Structure of an Truncated Transition metal Transporter | Descriptor: | COBALT (II) ION, Cobalamin biosynthesis protein CbiM, HEXANE-1,6-DIOL | Authors: | Yu, Y, Zhou, M.Z, Gu, J.K. | Deposit date: | 2013-08-08 | Release date: | 2014-03-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Planar substrate-binding site dictates the specificity of ECF-type nickel/cobalt transporters Cell Res., 24, 2014
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7WK2
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![BU of 7wk2 by Molmil](/molmil-images/mine/7wk2) | SARS-CoV-2 Omicron S-close | Descriptor: | Spike glycoprotein | Authors: | Li, J.W, Cong, Y. | Deposit date: | 2022-01-08 | Release date: | 2022-01-26 | Last modified: | 2022-05-04 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Molecular basis of receptor binding and antibody neutralization of Omicron. Nature, 604, 2022
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7W0G
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![BU of 7w0g by Molmil](/molmil-images/mine/7w0g) | Human PPAR delta ligand binding domain in complex with a synthetic agonist H11 | Descriptor: | 2-[2,6-dimethyl-4-[[5-oxidanylidene-4-[4-(trifluoromethyloxy)phenyl]-1,2,4-triazol-1-yl]methyl]phenoxy]-2-methyl-propanoic acid, Peroxisome proliferator-activated receptor delta | Authors: | Dai, L, Sun, H.B, Yuan, H.L, Feng, Z.Q. | Deposit date: | 2021-11-18 | Release date: | 2022-02-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (2.443 Å) | Cite: | Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPAR alpha / delta Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis. J.Med.Chem., 65, 2022
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