7WNH

Crystal structure of Nurr1 binding to NBRE

Summary for 7WNH

• Entry DOI: 10.2210/pdb7wnh/pdb
• Descriptor: Nuclear receptor subfamily 4 group A member 2, DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3'), DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3'), ... (5 entities in total)
• Functional Keywords: nurr1, nbre, dbd, lbd, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 198131.77

Authors

Zhao, M.,Xu, T.,Wang, N.,Guo, Y.,Liu, J. (deposition date: 2022-01-18, release date: 2023-01-25, Last modification date: 2023-11-29)

• Primary citation: Zhao, M.,Wang, N.,Guo, Y.,Li, J.,Yin, Y.,Dong, Y.,Zhu, J.,Peng, C.,Xu, T.,Liu, J.; Integrative analysis reveals structural basis for transcription activation of Nurr1 and Nurr1-RXR alpha heterodimer.; Proc.Natl.Acad.Sci.USA, 119:e2206737119-e2206737119, 2022; PubMed: 36442107; DOI: 10.1073/pnas.2206737119

Experimental method

X-RAY DIFFRACTION (3.1 Å)