7WNH

Crystal structure of Nurr1 binding to NBRE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Nuclear receptor subfamily 4 group A member 2	polymer	350	39604.8	4	UniProt (P43354) Pfam (PF00105) Pfam (PF00104)	Homo sapiens (human)	Immediate-early response protein NOT,Orphan nuclear receptor NURR1,Transcriptionally-inducible nuclear receptor
2	E, H, J, L (E, I, L, O)	DNA (5'-D(*CP*GP*CP*AP*TP*GP*AP*CP*CP*TP*TP*TP*TP*CP*GP*G)-3')	polymer	16	4865.2	4		synthetic construct
3	F, G, I, K (F, H, K, N)	DNA (5'-D(*CP*CP*GP*AP*AP*AP*AP*GP*GP*TP*CP*AP*TP*GP*CP*G)-3')	polymer	16	4932.2	4		synthetic construct
4	M, N, O, P, Q... (A, B, C, D)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
5	U, V, W, X, Y... (A, B, C, D, E...)	water	water		18.0	28	Chemie (HOH)

Sequence modifications

A, B, C, D: 258 - 598 (UniProt: P43354)

PDB	External Database	Details
Met 249	-	initiating methionine
Gly 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
His 254	-	expression tag
His 255	-	expression tag
His 256	-	expression tag
Met 257	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	197608.5
Non-Polymers*	Number of molecules	8
	Total formula weight	523.3
All*	Total formula weight	198131.8

*Water molecules are not included.