3LO6
Crystal structure of human alpha-defensin 1 (W26Aba mutant)
Summary for 3LO6
| Entry DOI | 10.2210/pdb3lo6/pdb |
| Related | 3GNY 3LO1 3LO2 3LO4 3LO9 3LOE |
| Descriptor | Neutrophil defensin 1, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ... (4 entities in total) |
| Functional Keywords | antimicrobial peptide, human alpha defensin 1, human neutrophil peptide 1, hnp1, antibiotic, antimicrobial, antiviral defense, defensin, disulfide bond, fungicide, phosphoprotein, secreted, antimicrobial protein |
| Cellular location | Secreted: P59665 |
| Total number of polymer chains | 2 |
| Total formula weight | 6891.09 |
| Authors | Pazgier, M.,Lu, W. (deposition date: 2010-02-03, release date: 2010-03-09, Last modification date: 2023-11-22) |
| Primary citation | Wei, G.,Pazgier, M.,de Leeuw, E.,Rajabi, M.,Li, J.,Zou, G.,Jung, G.,Yuan, W.,Lu, W.Y.,Lehrer, R.I.,Lu, W. Trp-26 imparts functional versatility to human alpha-defensin HNP1. J.Biol.Chem., 285:16275-16285, 2010 Cited by PubMed: 20220136DOI: 10.1074/jbc.M110.102749 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.56 Å) |
Structure validation
Download full validation report
