3GNY

Crystal structure of human alpha-defensin 1 (HNP1)

Summary for 3GNY

Entry DOI	10.2210/pdb3gny/pdb
Related	1DFN 2PM1 2PM4 2PM5 3GO0
Descriptor	Neutrophil defensin 1, CHLORIDE ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	antimicrobial peptide, human alpha defensin 1, human neutrophil peptide 1, hnp1, antibiotic, antimicrobial, antiviral defense, defensin, disulfide bond, fungicide, phosphoprotein, secreted, antimicrobial protein
Biological source	Homo sapiens (Human)
Cellular location	Secreted: P59665
Total number of polymer chains	2
Total formula weight	7123.86
Authors	Pazgier, M.,Lu, W.-Y. (deposition date: 2009-03-18, release date: 2009-07-28, Last modification date: 2023-09-06)
Primary citation	Wei, G.,de Leeuw, E.,Pazgier, M.,Yuan, W.,Zou, G.,Wang, J.,Ericksen, B.,Lu, W.Y.,Lehrer, R.I.,Lu, W. Through the looking glass, mechanistic insights from enantiomeric human defensins. J.Biol.Chem., 284:29180-29192, 2009 Cited by PubMed: 19640840 DOI: 10.1074/jbc.M109.018085 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.56 Å)

Structure validation