5F18
 
 | | Structural basis of Ebola virus entry: viral glycoprotein bound to its endosomal receptor Niemann-Pick C1 | | Descriptor: | Niemann-Pick C1 protein | | Authors: | Wang, H, Shi, Y, Song, J, Qi, J, Lu, G, Yan, J, Gao, G.F. | | Deposit date: | 2015-11-30 | | Release date: | 2016-01-20 | | Last modified: | 2016-01-27 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Ebola Viral Glycoprotein Bound to Its Endosomal Receptor Niemann-Pick C1.
Cell, 164, 2016
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5C6D
 | | Crystal structure of USP7 in complex with UHRF1 | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Ubiquitin carboxyl-terminal hydrolase 7 | | Authors: | Zhang, Z.-M, Song, J. | | Deposit date: | 2015-06-22 | | Release date: | 2015-09-09 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.292 Å) | | Cite: | An Allosteric Interaction Links USP7 to Deubiquitination and Chromatin Targeting of UHRF1.
Cell Rep, 12, 2015
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6KNR
 | | Crystal structure of Estrogen-related receptor gamma ligand-binding domain with DN200699 | | Descriptor: | (E)-4-(1-(4-(1-cyclopropylpiperidin-4-yl)phenyl)-5-hydroxy-2-phenylpent-1-en-1-yl)phenol, Estrogen-related receptor gamma | | Authors: | Yoon, H, Kim, J, Chin, J, Song, J, Cho, S.J. | | Deposit date: | 2019-08-07 | | Release date: | 2020-08-12 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.804 Å) | | Cite: | An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Eur.J.Med.Chem., 205, 2020
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7JLT
 | | Crystal Structure of SARS-CoV-2 NSP7-NSP8 complex. | | Descriptor: | Non-structural protein 7, Non-structural protein 8 | | Authors: | Biswal, M, Hai, R, Song, J. | | Deposit date: | 2020-07-30 | | Release date: | 2020-08-26 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
Nucleic Acids Res., 49, 2021
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5EJX
 | | X-ray Free Electron Laser Structure of Cytochrome C Peroxidase | | Descriptor: | Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ... | | Authors: | Doukov, T, Soltis, S.M, Baxter, E.L, Cohen, A, Song, J, McPhillips, S, Poulos, T.L, Meharenna, Y.T, Chreifi, G. | | Deposit date: | 2015-11-02 | | Release date: | 2016-01-20 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5EJT
 | | Thermally annealed ferryl Cytochrome C Peroxidase crystal structure | | Descriptor: | Cytochrome c peroxidase, mitochondrial, PHOSPHATE ION, ... | | Authors: | Doukov, T, Soltis, S.M, Baxter, E.L, Cohen, A, Song, J, McPhillips, S, Poulos, T.L, Meharenna, Y.T, Chreifi, G. | | Deposit date: | 2015-11-02 | | Release date: | 2016-01-20 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Crystal structure of the pristine peroxidase ferryl center and its relevance to proton-coupled electron transfer.
Proc.Natl.Acad.Sci.USA, 113, 2016
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6A6K
 | | Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000 | | Descriptor: | 3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma | | Authors: | Yoon, H, Kim, J, Chin, J, Cho, S.J, Song, J. | | Deposit date: | 2018-06-28 | | Release date: | 2019-04-10 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-gamma Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
J. Med. Chem., 62, 2019
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5Y70
 | | NMR structure of KMP11 in DPC micelle | | Descriptor: | Kinetoplastid membrane protein 11 | | Authors: | Lu, Y, Lim, L.Z, Song, J. | | Deposit date: | 2017-08-16 | | Release date: | 2018-02-07 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Kinetoplastid membrane protein-11 adopts a four-helix bundle fold in DPC micelle.
FEBS Lett., 591, 2017
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5XQ5
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5YX2
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1VJH
 | | Crystal structure of gene product of At1g24000 from Arabidopsis thaliana | | Descriptor: | Bet v I allergen family | | Authors: | Wesenberg, G.E, Smith, D.W, Phillips Jr, G.N, Johnson, K.A, Bingman, C.A, Center for Eukaryotic Structural Genomics (CESG) | | Deposit date: | 2004-02-20 | | Release date: | 2004-03-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | 1H, 15N and 13C resonance assignments of the putative Bet v 1 family protein At1g24000.1 from Arabidopsis thaliana.
J.Biomol.Nmr, 32, 2005
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6YEJ
 | | Cryo-EM structure of the Full-length disease type human Huntingtin | | Descriptor: | Huntingtin | | Authors: | Tame, G, Jung, T, Dal Perraro, M, Hebert, H, Song, J. | | Deposit date: | 2020-03-24 | | Release date: | 2020-12-16 | | Method: | ELECTRON MICROSCOPY (18.200001 Å) | | Cite: | The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain.
Structure, 28, 2020
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4PNJ
 | | Recombinant Sperm Whale P6 Myoglobin Solved with Single Pulse Free Electron Laser Data | | Descriptor: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION | | Authors: | Cohen, A, Gonzalez, A, Lam, W, Lyubimov, A, Sauter, N, Tsai, Y, Uervirojnangkoorn, M, Brunger, A, Soltis, M. | | Deposit date: | 2014-05-23 | | Release date: | 2014-11-05 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (1.36 Å) | | Cite: | Goniometer-based femtosecond crystallography with X-ray free electron lasers.
Proc.Natl.Acad.Sci.USA, 111, 2014
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8EIH
 | | Cryo-EM structure of human DNMT3B homo-tetramer (form I) | | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Lu, J.W, Song, J.K. | | Deposit date: | 2022-09-15 | | Release date: | 2023-09-20 | | Last modified: | 2024-04-03 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
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8EII
 | | Cryo-EM structure of human DNMT3B homo-tetramer (form II) | | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Lu, J.W, Song, J.K. | | Deposit date: | 2022-09-15 | | Release date: | 2023-09-20 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
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8EIK
 | | Cryo-EM structure of human DNMT3B homo-hexamer | | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Lu, J.W, Song, J.K. | | Deposit date: | 2022-09-15 | | Release date: | 2023-09-20 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.19 Å) | | Cite: | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
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8EIJ
 | | Cryo-EM structure of human DNMT3B homo-trimer | | Descriptor: | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION | | Authors: | Lu, J.W, Song, J.K. | | Deposit date: | 2022-09-15 | | Release date: | 2023-09-20 | | Last modified: | 2023-12-20 | | Method: | ELECTRON MICROSCOPY (3.34 Å) | | Cite: | Structural basis for the allosteric regulation and dynamic assembly of DNMT3B.
Nucleic Acids Res., 51, 2023
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3GXU
 | | Crystal structure of Eph receptor and ephrin complex | | Descriptor: | Ephrin type-A receptor 4, Ephrin-B2 | | Authors: | Qin, H.N, Song, J.X. | | Deposit date: | 2009-04-03 | | Release date: | 2009-10-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural characterization of the EphA4-ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity
J.Biol.Chem., 2009
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8DS8
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6AGO
 | | Crystal structure of MRG15-ASH1L Histone methyltransferase complex | | Descriptor: | Histone-lysine N-methyltransferase ASH1L, Mortality factor 4 like 1, S-ADENOSYLMETHIONINE, ... | | Authors: | Lee, Y, Song, J. | | Deposit date: | 2018-08-13 | | Release date: | 2019-03-13 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.103 Å) | | Cite: | Structural Basis of MRG15-Mediated Activation of the ASH1L Histone Methyltransferase by Releasing an Autoinhibitory Loop.
Structure, 27, 2019
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6WW5
 | | Structure of VcINDY-Na-Fab84 in nanodisc | | Descriptor: | 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, DASS family sodium-coupled anion symporter, Fab84 Heavy Chain, ... | | Authors: | Sauer, D.B, Marden, J, Song, J.M, Koide, A, Koide, S, Wang, D.N. | | Deposit date: | 2020-05-07 | | Release date: | 2020-09-16 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural basis for the reaction cycle of DASS dicarboxylate transporters.
Elife, 9, 2020
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5JHM
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5JHL
 | | Crystal structure of zika virus envelope protein in complex with a flavivirus broadly-protective antibody | | Descriptor: | Antibody Heavy chain, antibody Light chain, envelope protein | | Authors: | Dai, L, Shi, Y, Qi, J, Gao, G.F. | | Deposit date: | 2016-04-21 | | Release date: | 2016-05-11 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structures of the Zika Virus Envelope Protein and Its Complex with a Flavivirus Broadly Protective Antibody.
Cell Host Microbe, 19, 2016
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7LO8
 | | NorA in complex with Fab36 | | Descriptor: | Fab36 Heavy Chain, Fab36 Light Chain, Quinolone resistance protein NorA | | Authors: | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | | Deposit date: | 2021-02-09 | | Release date: | 2022-04-20 | | Last modified: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (3.16 Å) | | Cite: | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
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7LO7
 | | NorA in complex with Fab25 | | Descriptor: | Fab25 Heavy Chain, Fab25 Light Chain, Quinolone resistance protein NorA | | Authors: | Brawley, D.N, Sauer, D.B, Song, J.M, Koide, A, Koide, S, Traaseth, N.J, Wang, D.N. | | Deposit date: | 2021-02-09 | | Release date: | 2022-04-20 | | Last modified: | 2022-07-13 | | Method: | ELECTRON MICROSCOPY (3.74 Å) | | Cite: | Structural basis for inhibition of the drug efflux pump NorA from Staphylococcus aureus.
Nat.Chem.Biol., 18, 2022
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