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PDB: 141 results

2ISH
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BU of 2ish by Molmil
Botulinum Neurotoxin A Light Chain WT Crystal Form C
Descriptor: Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T, Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISE
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BU of 2ise by Molmil
Botulinum Neurotoxin A Light Chain WT Crystal Form A
Descriptor: Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T, Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
2ISG
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BU of 2isg by Molmil
Botulinum Neurotoxin A Light Chain WT Crystal Form B
Descriptor: NICKEL (II) ION, Neurotoxin BoNT/A, ZINC ION
Authors:Brunger, A.T, Stegmann, C.M.
Deposit date:2006-10-17
Release date:2006-11-07
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons.
J.Biol.Chem., 282, 2007
5FOY
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BU of 5foy by Molmil
De novo structure of the binary mosquito larvicide BinAB at pH 7
Descriptor: 41.9 KDA INSECTICIDAL TOXIN, LARVICIDAL TOXIN 51 KDA PROTEIN
Authors:Colletier, J.P, Sawaya, M.R, Gingery, M, Rodriguez, J.A, Cascio, D, Brewster, A.S, Michels-Clark, T, Boutet, S, Williams, G.J, Messerschmidt, M, DePonte, D.P, Sierra, R.G, Laksmono, H, Koglin, J.E, Hunter, M.S, W Park, H, Uervirojnangkoorn, M, Bideshi, D.L, Brunger, A.T, Federici, B.A, Sauter, N.K, Eisenberg, D.S.
Deposit date:2015-11-26
Release date:2016-10-05
Last modified:2019-08-28
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:De Novo Phasing with X-Ray Laser Reveals Mosquito Larvicide Binab Structure.
Nature, 539, 2016
6PNP
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BU of 6pnp by Molmil
Crystal structure of the splice insert-free neurexin-1 LNS2 domain in complex with neurexophilin-1
Descriptor: Neurexin-1, Neurexophilin-1
Authors:Wilson, S.C, White, K.I, Zhou, Q, Brunger, A.T.
Deposit date:2019-07-02
Release date:2019-10-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.
Embo J., 38, 2019
7RZU
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BU of 7rzu by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with A942S mutation
Descriptor: SARS-CoV-2 HR1 A942S linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZS
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BU of 7rzs by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with L938F mutation
Descriptor: SARS-CoV-2 HR1 L938F linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.52 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZR
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BU of 7rzr by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with D936Y mutation
Descriptor: SARS-CoV-2 HR1 D936Y linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.27 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZT
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BU of 7rzt by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with S940F mutation
Descriptor: SARS-CoV-2 HR1 S940F linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.35 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZV
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BU of 7rzv by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with V1176F mutation
Descriptor: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.11 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
7RZQ
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BU of 7rzq by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex
Descriptor: SARS-CoV-2 HR1 linked to a scaffold,Spike protein S2', Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2021-08-27
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.09 Å)
Cite:Structural conservation among variants of the SARS-CoV-2 spike postfusion bundle.
Proc.Natl.Acad.Sci.USA, 119, 2022
8CZI
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BU of 8czi by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with extended HR2
Descriptor: Scaffolded Spike protein S2' HR1, Spike protein S2' HR2
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-05-24
Release date:2022-09-07
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.22 Å)
Cite:Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein.
Proc.Natl.Acad.Sci.USA, 119, 2022
1GTO
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BU of 1gto by Molmil
HIGH RESOLUTION STRUCTURE OF A HYPERSTABLE HELICAL BUNDLE PROTEIN MUTANT
Descriptor: ROP
Authors:Agrawal, V, Predki, P, Regan, L, Brunger, A.T.
Deposit date:1996-04-23
Release date:1997-01-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Amino-acid substitutions in a surface turn modulate protein stability.
Nat.Struct.Biol., 3, 1996
4WMG
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BU of 4wmg by Molmil
Structure of hen egg-white lysozyme from a microfludic harvesting device using synchrotron radiation (2.5A)
Descriptor: Lysozyme C
Authors:Lyubimov, A.Y, Murray, T.D, Koehl, A, Uervirojnangkoorn, M, Zeldin, O.B, Cohen, A.E, Soltis, S.M, Baxter, E.M, Brewster, A.S, Sauter, N.K, Brunger, A.T, Berger, J.M.
Deposit date:2014-10-08
Release date:2015-04-22
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Capture and X-ray diffraction studies of protein microcrystals in a microfluidic trap array.
Acta Crystallogr.,Sect.D, 71, 2015
8FA1
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BU of 8fa1 by Molmil
Cryo-EM structure of the SARS-CoV-2 HR1HR2 fusion core complex with N969K mutation
Descriptor: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2' HR2
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-11-25
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.51 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FA2
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BU of 8fa2 by Molmil
Cryo-EM structure of the SARS-CoV-2 Omicron HR1-42G complex
Descriptor: Scaffolded Spike protein S2' HR1, Spike protein S2' 42G
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-11-25
Release date:2023-03-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
1QQE
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BU of 1qqe by Molmil
CRYSTAL STRUCTURE OF THE VESICULAR TRANSPORT PROTEIN SEC17
Descriptor: VESICULAR TRANSPORT PROTEIN SEC17
Authors:Rice, L.M, Brunger, A.T.
Deposit date:1999-06-04
Release date:1999-09-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of the vesicular transport protein Sec17: implications for SNAP function in SNARE complex disassembly.
Mol.Cell, 4, 1999
7TIK
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BU of 7tik by Molmil
Structure of the SARS-CoV-2 Omicron spike post-fusion bundle
Descriptor: Ferritin, Dps family protein and Spike protein S2' chimera, Spike protein S2'
Authors:Yang, K, Brunger, A.T.
Deposit date:2022-01-13
Release date:2022-04-06
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.4 Å)
Cite:Structure-based design of a SARS-CoV-2 Omicron-specific inhibitor.
Proc.Natl.Acad.Sci.USA, 120, 2023
4WY4
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BU of 4wy4 by Molmil
Crystal structure of autophagic SNARE complex
Descriptor: Synaptosomal-associated protein 29, Syntaxin-17, Vesicle-associated membrane protein 8
Authors:Zhao, M, Brunger, A.T.
Deposit date:2014-11-15
Release date:2015-02-11
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes.
Nature, 520, 2015
9BRU
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BU of 9bru by Molmil
Intact V-ATPase State 1 in synaptophysin knock-out isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRT
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BU of 9brt by Molmil
Intact V-ATPase State 1 and synaptophysin complex in mouse brain isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRS
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BU of 9brs by Molmil
Intact V-ATPase State 2 in synaptophysin knock-out isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRA
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BU of 9bra by Molmil
Intact V-ATPase State 2 and synaptophysin complex in mouse brain isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRR
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BU of 9brr by Molmil
Intact V-ATPase State 3 in synaptophysin knock-out isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, V-type proton ATPase 116 kDa subunit a 1, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024
9BRQ
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BU of 9brq by Molmil
Intact V-ATPase State 3 and synaptophysin complex in mouse brain isolated synaptic vesicles
Descriptor: Renin receptor cytoplasmic fragment, Ribonuclease kappa, Synaptophysin, ...
Authors:Wang, C, Jiang, W, Yang, K, Wang, X, Guo, Q, Brunger, A.T.
Deposit date:2024-05-11
Release date:2024-06-19
Last modified:2024-08-07
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structure and topography of the synaptic V-ATPase-synaptophysin complex.
Nature, 631, 2024

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