2ISE
Botulinum Neurotoxin A Light Chain WT Crystal Form A
Summary for 2ISE
Entry DOI | 10.2210/pdb2ise/pdb |
Related | 2ISG 2ISH |
Descriptor | Neurotoxin BoNT/A, ZINC ION (3 entities in total) |
Functional Keywords | botulinum neurotoxin, toxin |
Biological source | Clostridium botulinum |
Total number of polymer chains | 2 |
Total formula weight | 96457.49 |
Authors | Brunger, A.T.,Stegmann, C.M. (deposition date: 2006-10-17, release date: 2006-11-07, Last modification date: 2023-08-30) |
Primary citation | Burnett, J.C.,Ruthel, G.,Stegmann, C.M.,Panchal, R.G.,Nguyen, T.L.,Hermone, A.R.,Stafford, R.G.,Lane, D.J.,Kenny, T.A.,McGrath, C.F.,Wipf, P.,Stahl, A.M.,Schmidt, J.J.,Gussio, R.,Brunger, A.T.,Bavari, S. Inhibition of metalloprotease botulinum serotype A from a pseudo-peptide binding mode to a small molecule that is active in primary neurons. J.Biol.Chem., 282:5004-5014, 2007 Cited by PubMed: 17092934DOI: 10.1074/jbc.M608166200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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