7EEZ
 
 | | crystal structure of maize SHH2 SAWADEE domain | | Descriptor: | HB transcription factor, ZINC ION | | Authors: | Wang, Y, Du, J. | | Deposit date: | 2021-03-20 | | Release date: | 2021-06-30 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.902 Å) | | Cite: | Recognition of H3K9me1 by maize RNA-directed DNA methylation factor SHH2.
J Integr Plant Biol, 63, 2021
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7EF0
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3Q7K
 | | Formate Channel FocA from Salmonella typhimurium | | Descriptor: | FORMIC ACID, Probable formate transporter | | Authors: | Lue, W, Du, J, Wacker, T, Gerbig-Smentek, E, Andrade, S.L.A, Einsle, O. | | Deposit date: | 2011-01-05 | | Release date: | 2011-04-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | pH-dependent gating in a FocA formate channel
Science, 332, 2011
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6UIW
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6UIV
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6UIX
 | | Cryo-EM structure of human CALHM2 gap junction | | Descriptor: | Calcium homeostasis modulator protein 2 | | Authors: | Lu, W, Du, J, Choi, W. | | Deposit date: | 2019-10-01 | | Release date: | 2019-11-27 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The structures and gating mechanism of human calcium homeostasis modulator 2.
Nature, 576, 2019
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6WBK
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6WBN
 | | Cryo-EM structure of human Pannexin 1 channel N255A mutant, gap junction | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, DIACYL GLYCEROL, ... | | Authors: | Lu, W, Du, J, Ruan, Z. | | Deposit date: | 2020-03-26 | | Release date: | 2020-06-03 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
Nature, 584, 2020
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6WBM
 | | Cryo-EM structure of human Pannexin 1 channel N255A mutant | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, DIACYL GLYCEROL, ... | | Authors: | Lu, W, Du, J, Ruan, Z. | | Deposit date: | 2020-03-26 | | Release date: | 2020-06-03 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (2.86 Å) | | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
Nature, 584, 2020
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6WBL
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6WBI
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6WBF
 | | Cryo-EM structure of wild type human Pannexin 1 channel | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Lu, W, Du, J, Ruan, Z. | | Deposit date: | 2020-03-26 | | Release date: | 2020-06-03 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.83 Å) | | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
Nature, 584, 2020
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6WBG
 | | Cryo-EM structure of human Pannexin 1 channel with its C-terminal tail cleaved by caspase-7 | | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | | Authors: | Lu, W, Du, J, Ruan, Z. | | Deposit date: | 2020-03-26 | | Release date: | 2020-06-03 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.97 Å) | | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating.
Nature, 584, 2020
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3WMI
 | | Crystal structure of EIAV wild type gp45 | | Descriptor: | EIAV gp45 wild type | | Authors: | Liu, X, Du, J, Qiao, W. | | Deposit date: | 2013-11-19 | | Release date: | 2014-11-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A mutation associated with EIAV vaccine strain within heptad repeat of EIAV gp45 provides insight into vaccine development for HIV
To be Published
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6MAL
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5WP6
 | | Cryo-EM structure of a human TRPM4 channel in complex with calcium and decavanadate | | Descriptor: | DECAVANADATE, Transient receptor potential cation channel subfamily M member 4 | | Authors: | Winkler, P.A, Huang, Y, Sun, W, Du, J, Lu, W. | | Deposit date: | 2017-08-03 | | Release date: | 2017-12-13 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Electron cryo-microscopy structure of a human TRPM4 channel.
Nature, 552, 2017
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5UP2
 | | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981, MK-801 and a GluN2B-specific Fab, at pH 6.5 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GluN2B-specific Fab, ... | | Authors: | Lu, W, Du, J, Goehring, A, Gouaux, E. | | Deposit date: | 2017-02-01 | | Release date: | 2017-03-22 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (6 Å) | | Cite: | Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Science, 355, 2017
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4FC4
 | | FNT family ion channel | | Descriptor: | Nitrite transporter NirC, octyl beta-D-glucopyranoside | | Authors: | Lue, W, Schwarzer, N, Du, J, Gerbig-Smentek, E, Andrade, S.L.A, Einsle, O. | | Deposit date: | 2012-05-24 | | Release date: | 2012-11-21 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Structural and functional characterization of the nitrite channel NirC from Salmonella typhimurium.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5UOW
 | | Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a GluN2B-specific Fab, at pH 6.5 | | Descriptor: | (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | | Authors: | Lu, W, Du, J, Goehring, A, Gouaux, E. | | Deposit date: | 2017-02-01 | | Release date: | 2017-03-22 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.
Science, 355, 2017
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3WMJ
 | | Crystal structure of EIAV vaccine gp45 | | Descriptor: | EIAV vaccine gp45 | | Authors: | Liu, X, Du, J, Qiao, W. | | Deposit date: | 2013-11-19 | | Release date: | 2014-11-19 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.998 Å) | | Cite: | A mutation associated with EIAV vaccine strain within heptad repeat of EIAV gp45 provides insight into vaccine development for HIV
To be Published
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6CUD
 | | Structure of the human TRPC3 in a lipid-occupied, closed state | | Descriptor: | (2R)-3-hydroxypropane-1,2-diyl dihexanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Lu, W, Du, J, Fan, C, Choi, W. | | Deposit date: | 2018-03-25 | | Release date: | 2018-05-16 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of the human lipid-gated cation channel TRPC3.
Elife, 7, 2018
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4IUR
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5YKO
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5YKN
 | | crystal structure of Arabidopsis thaliana JMJ14 catalytic domain | | Descriptor: | NICKEL (II) ION, Probable lysine-specific demethylase JMJ14, ZINC ION | | Authors: | Yang, Z, Du, J. | | Deposit date: | 2017-10-15 | | Release date: | 2017-12-27 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structure of the Arabidopsis JMJ14-H3K4me3 Complex Provides Insight into the Substrate Specificity of KDM5 Subfamily Histone Demethylases.
Plant Cell, 30, 2018
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7MBR
 | | Cryo-EM structure of zebrafish TRPM5 in the presence of 6 uM calcium (apo state) | | Descriptor: | (25R)-14beta,17beta-spirost-5-en-3beta-ol, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Ruan, Z, Lu, W, Du, J, Haley, E. | | Deposit date: | 2021-04-01 | | Release date: | 2021-07-07 | | Last modified: | 2025-05-28 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Structures of the TRPM5 channel elucidate mechanisms of activation and inhibition.
Nat.Struct.Mol.Biol., 28, 2021
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