6WBL

Cryo-EM structure of human Pannexin 1 channel with deletion of N-terminal helix and C-terminal tail, in complex with CBX

Summary for 6WBL

Entry DOI	10.2210/pdb6wbl/pdb
EMDB information	21588 21589 21590 21591 21592 21593 21594 21595 21596 21597 21598
Descriptor	Pannexin-1, CARBENOXOLONE (2 entities in total)
Functional Keywords	ion channel, transport protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	7
Total formula weight	294193.00
Authors	Lu, W.,Du, J.,Ruan, Z. (deposition date: 2020-03-26, release date: 2020-06-03, Last modification date: 2024-03-06)
Primary citation	Ruan, Z.,Orozco, I.J.,Du, J.,Lu, W. Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature, 584:646-651, 2020 Cited by PubMed: 32494015 DOI: 10.1038/s41586-020-2357-y PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.13 Å)

Structure validation