5XYZ
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![BU of 5xyz by Molmil](/molmil-images/mine/5xyz) | The structure of human BTK kinase domain in complex with a covalent inhibitor | Descriptor: | N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide, Tyrosine-protein kinase BTK | Authors: | Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Xie, Y.T, Li, L, Qi, X.B, Huang, N. | Deposit date: | 2017-07-11 | Release date: | 2018-05-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. J. Med. Chem., 60, 2017
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5XYX
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![BU of 5xyx by Molmil](/molmil-images/mine/5xyx) | The structure of p38 alpha in complex with a triazol inhibitor | Descriptor: | Mitogen-activated protein kinase 14, N-(2-chloro-6-fluorobenzyl)-5-(furan-2-yl)-2H-1,2,4-triazol-3-amine | Authors: | Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Li, L, Qi, X.B, Huang, N. | Deposit date: | 2017-07-11 | Release date: | 2018-01-17 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. J. Med. Chem., 60, 2017
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5XYY
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![BU of 5xyy by Molmil](/molmil-images/mine/5xyy) | The structure of p38 alpha in complex with a triazol inhibitor | Descriptor: | 3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-4H-1,2,4-triazol-3-yl)phenol, Mitogen-activated protein kinase 14 | Authors: | Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Li, L, Qi, X.B, Huang, N. | Deposit date: | 2017-07-11 | Release date: | 2018-01-17 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. J. Med. Chem., 60, 2017
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7XJG
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![BU of 7xjg by Molmil](/molmil-images/mine/7xjg) | Cryo-EM structure of E.coli retron-Ec86 in complex with its effector at 2.5 angstrom | Descriptor: | DNA (105-MER), MAGNESIUM ION, RNA (14-MER), ... | Authors: | Wang, Y.J, Guan, Z.Y, Zou, T.T. | Deposit date: | 2022-04-17 | Release date: | 2022-09-14 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism. Nat Microbiol, 7, 2022
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2M9M
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![BU of 2m9m by Molmil](/molmil-images/mine/2m9m) | Solution Structure of ERCC4 domain of human FAAP24 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | Deposit date: | 2013-06-18 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
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8TXC
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![BU of 8txc by Molmil](/molmil-images/mine/8txc) | |
8TX1
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![BU of 8tx1 by Molmil](/molmil-images/mine/8tx1) | |
8TXB
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![BU of 8txb by Molmil](/molmil-images/mine/8txb) | |
2M9N
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![BU of 2m9n by Molmil](/molmil-images/mine/2m9n) | Solution Structure of (HhH)2 domain of human FAAP24 | Descriptor: | Fanconi anemia-associated protein of 24 kDa | Authors: | Wu, F, Han, X, Shi, C, Gong, W, Tian, C. | Deposit date: | 2013-06-18 | Release date: | 2013-09-18 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structure analysis of FAAP24 reveals single-stranded DNA-binding activity and domain functions in DNA damage response. Cell Res., 23, 2013
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3RYT
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![BU of 3ryt by Molmil](/molmil-images/mine/3ryt) | The Plexin A1 intracellular region in complex with Rac1 | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plexin-A1, ... | Authors: | Zhang, X, He, H. | Deposit date: | 2011-05-11 | Release date: | 2012-01-18 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.582 Å) | Cite: | Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization. Sci.Signal., 5, 2012
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5EKJ
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![BU of 5ekj by Molmil](/molmil-images/mine/5ekj) | |
5EKM
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![BU of 5ekm by Molmil](/molmil-images/mine/5ekm) | |
5EKH
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![BU of 5ekh by Molmil](/molmil-images/mine/5ekh) | |
7W92
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![BU of 7w92 by Molmil](/molmil-images/mine/7w92) | Open state of SARS-CoV-2 Delta variant spike protein | Descriptor: | Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W9E
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![BU of 7w9e by Molmil](/molmil-images/mine/7w9e) | SARS-CoV-2 Delta S-8D3 | Descriptor: | Anti-H5N1 hemagglutinin monoclonal anitbody H5M9 heavy chain, Spike glycoprotein, The light chain of 8D3 fab | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W99
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![BU of 7w99 by Molmil](/molmil-images/mine/7w99) | SARS-CoV-2 Delta S-ACE2-C2a | Descriptor: | Angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W94
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7W9C
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![BU of 7w9c by Molmil](/molmil-images/mine/7w9c) | SARS-CoV-2 Delta S-ACE2-C3 | Descriptor: | Angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W98
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![BU of 7w98 by Molmil](/molmil-images/mine/7w98) | SARS-CoV-2 Delta S-ACE2-C1 | Descriptor: | Angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W9B
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![BU of 7w9b by Molmil](/molmil-images/mine/7w9b) | SARS-CoV-2 Delta S-ACE2-C2b | Descriptor: | Angiotensin-converting enzyme 2, Spike glycoprotein | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W9F
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![BU of 7w9f by Molmil](/molmil-images/mine/7w9f) | SARS-CoV-2 Delta S-RBD-8D3 | Descriptor: | Spike protein S1, The heavy chain of 8D3, The light chain of 8D3 | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7W9I
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![BU of 7w9i by Molmil](/molmil-images/mine/7w9i) | SARS-CoV-2 Delta S-RBD-ACE2 | Descriptor: | Angiotensin-converting enzyme 2, Spike protein S1 | Authors: | Cong, Y, Liu, C.X. | Deposit date: | 2021-12-09 | Release date: | 2022-01-12 | Last modified: | 2022-03-02 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis for SARS-CoV-2 Delta variant recognition of ACE2 receptor and broadly neutralizing antibodies. Nat Commun, 13, 2022
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7WOS
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![BU of 7wos by Molmil](/molmil-images/mine/7wos) | The state 3 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOQ
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![BU of 7woq by Molmil](/molmil-images/mine/7woq) | The state 1 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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7WOU
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![BU of 7wou by Molmil](/molmil-images/mine/7wou) | The state 4 of Omicron Spike with bispecific antibody FD01 | Descriptor: | 16L9 Fv, 2-acetamido-2-deoxy-beta-D-glucopyranose, GW01 Fv, ... | Authors: | Zhang, X, Zhan, W.Q, Chen, Z.G, Sun, L. | Deposit date: | 2022-01-22 | Release date: | 2022-11-30 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Combating the SARS-CoV-2 Omicron (BA.1) and BA.2 with potent bispecific antibodies engineered from non-Omicron neutralizing antibodies Cell Discov, 8, 2022
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