6KVK
 
 | | Crystal structure of UDP-Sm-SrUGT76G1 | | Descriptor: | Steviolmonoside, UDP-glycosyltransferase 76G1, URIDINE-5'-DIPHOSPHATE | | Authors: | Li, J.X, Liu, Z.F, Wang, Y, Zhang, P. | | Deposit date: | 2019-09-04 | | Release date: | 2019-11-20 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.397 Å) | | Cite: | Structural Insights into the Catalytic Mechanism of a Plant Diterpene Glycosyltransferase SrUGT76G1.
Plant Commun., 1, 2020
|
|
7XIL
 | | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, B38 Fab heavy chain, B38 Fab light chain, ... | | Authors: | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | Deposit date: | 2022-04-13 | | Release date: | 2023-04-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | SARS-CoV-2-Beta-RBD and B38-GWP/P-VK antibody complex
To Be Published
|
|
7XIK
 | | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex | | Descriptor: | B38 Fab heavy chain, B38 Fab light chain, Spike protein S1 | | Authors: | Shi, R, Wang, Y, Wu, Z, Han, X, Yan, J. | | Deposit date: | 2022-04-13 | | Release date: | 2023-04-26 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.89 Å) | | Cite: | SARS-CoV-2-Omicron-RBD and B38-GWP/P-VK antibody complex
To Be Published
|
|
8IL4
 | |
8IL5
 | |
7YL3
 | | Structure of hIAPP-TF-type1 | | Descriptor: | Islet amyloid polypeptide | | Authors: | Li, D, Zhang, X, Wang, Y, Zhu, P. | | Deposit date: | 2022-07-25 | | Release date: | 2022-12-28 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
|
|
7YL0
 | | Structure of hIAPP-TF-type2 | | Descriptor: | Islet amyloid polypeptide | | Authors: | Li, D, Zhang, X, Wang, Y, Zhu, P. | | Deposit date: | 2022-07-25 | | Release date: | 2022-12-28 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | A new polymorphism of human amylin fibrils with similar protofilaments and a conserved core.
Iscience, 25, 2022
|
|
7YKW
 | |
7C3V
 | | Structure of a thermostable Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH) | | Descriptor: | Alcohol dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Dai, W, Ni, Y, Xu, G, Liu, Y, Wang, Y, Zhou, J. | | Deposit date: | 2020-05-14 | | Release date: | 2021-05-19 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.20042944 Å) | | Cite: | Structure of a thermostable Alcohol dehydrogenase from Kluyveromyces polyspora(KpADH)
To Be Published
|
|
7ZGO
 | | Cryo-EM structure of human NKCC1 (TM domain) | | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Nissen, P, Fenton, R, Neumann, C, Lindtoft Rosenbaek, L, Kock Flygaard, R, Habeck, M, Lykkegaard Karlsen, J, Wang, Y, Lindorff-Larsen, K, Gad, H, Hartmann, R, Lyons, J. | | Deposit date: | 2022-04-04 | | Release date: | 2022-10-05 | | Last modified: | 2024-11-20 | | Method: | ELECTRON MICROSCOPY (2.55 Å) | | Cite: | Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity.
Embo J., 41, 2022
|
|
8Z7X
 | | SLC19A3-Thiamine inward structure | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7R
 | | SLC19A3 apo structure | | Descriptor: | Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7T
 | | SLC19A3-Pyridoxine outward structure | | Descriptor: | 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z80
 | | SLC19A2-Pyridoxine inward structure | | Descriptor: | 4,5-bis(hydroxymethyl)-2-methyl-pyridin-3-ol, Thiamine transporter 1 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7S
 | | SLC19A3-thiamine outward structure | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.05 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7W
 | | SLC19A3-Metformin outward structure | | Descriptor: | Metformin, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.09 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7V
 | | Slc19A3-Amprolium outward structure | | Descriptor: | Amprolium, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7Y
 | | SLC19A3-Fedratinib inward structure | | Descriptor: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7U
 | | SLC19A3-Fedratinib outward structure | | Descriptor: | N-tert-butyl-3-{[5-methyl-2-({4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}amino)pyrimidin-4-yl]amino}benzenesulfonamide, Thiamine transporter 2 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
8Z7Z
 | | SLC19A2-Thiamine inward structure | | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, Thiamine transporter 1 | | Authors: | Li, P.P, Zhu, Z.N, Wang, Y, Gao, P, Qu, Q.H. | | Deposit date: | 2024-04-21 | | Release date: | 2025-01-08 | | Method: | ELECTRON MICROSCOPY (3.23 Å) | | Cite: | Substrate transport and drug interaction of human thiamine transporters SLC19A2/A3.
Nat Commun, 15, 2024
|
|
7D72
 | | Cryo-EM structures of human GMPPA/GMPPB complex bound to GDP-Mannose | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, Mannose-1-phosphate guanyltransferase alpha, ... | | Authors: | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | | Deposit date: | 2020-10-02 | | Release date: | 2021-05-05 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.4 Å) | | Cite: | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7D73
 | | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (State I) | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, ... | | Authors: | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, Cai, X, Mo, X, Gao, N, Jia, D. | | Deposit date: | 2020-10-02 | | Release date: | 2021-05-05 | | Last modified: | 2021-12-01 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis.
Nat.Struct.Mol.Biol., 28, 2021
|
|
7D74
 | | Cryo-EM structure of GMPPA/GMPPB complex bound to GTP (state II) | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Mannose-1-phosphate guanyltransferase alpha, Mannose-1-phosphate guanyltransferase beta | | Authors: | Zheng, L, Liu, Z, Wang, Y, Yang, F, Wang, J, Qing, J, cai, X, Mo, X, Gao, N, Jia, D. | | Deposit date: | 2020-10-02 | | Release date: | 2021-05-19 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structures of human GMPPA-GMPPB complex reveal how cells maintain GDP-mannose homeostasis.
Nat.Struct.Mol.Biol., 28, 2021
|
|
2JJ3
 | | Estrogen receptor beta ligand binding domain in complex with a Benzopyran agonist | | Descriptor: | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL, ESTROGEN RECEPTOR BETA | | Authors: | Norman, B.H, Richardson, T.I, Dodge, J.A, Pfeifer, L.A, Durst, G.L, Wang, Y, Durbin, J.D, Krishnan, V, Dinn, S.R, Liu, S, Reilly, J.E, Ryter, K.T. | | Deposit date: | 2007-07-03 | | Release date: | 2007-08-07 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (2.28 Å) | | Cite: | Benzopyrans as Selective Estrogen Receptor Beta Agonists (Serbas). Part 4: Functionalization of the Benzopyran A-Ring.
Bioorg.Med.Chem.Lett., 17, 2007
|
|
2LF0
 | | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering, NESG target SfR339/OCSP target sf3636 | | Descriptor: | Uncharacterized protein yibL | | Authors: | Wu, B, Lemak, A, Yee, A, Lee, H, Gutmanas, A, Semesi, A, Garcia, M, Fang, X, Wang, Y, Prestegard, J.H, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP) | | Deposit date: | 2011-06-27 | | Release date: | 2011-07-13 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Solution structure of sf3636, a two-domain unknown function protein from Shigella flexneri 2a, determined by joint refinement of NMR, residual dipolar couplings and small-angle X-ray scattering
To be Published
|
|
