6MDW
 
 | | Mechanism of protease dependent DPC repair | | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CITRATE ANION, ... | | Authors: | Li, F, Raczynska, J, Chen, Z, Yu, H. | | Deposit date: | 2018-09-05 | | Release date: | 2019-04-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
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6WG3
 | | Cryo-EM structure of human Cohesin-NIPBL-DNA complex | | Descriptor: | Cohesin subunit SA-1, DNA (51-MER), Double-strand-break repair protein rad21 homolog, ... | | Authors: | Shi, Z.B, Gao, H, Bai, X.C, Yu, H. | | Deposit date: | 2020-04-04 | | Release date: | 2020-05-20 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (5.3 Å) | | Cite: | Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
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6WGE
 | | Cryo-EM structure of human Cohesin-NIPBL-DNA complex without STAG1 | | Descriptor: | DNA (43-MER), Double-strand-break repair protein rad21 homolog, MAGNESIUM ION, ... | | Authors: | Shi, Z.B, Gao, H, Bai, X.C, Yu, H. | | Deposit date: | 2020-04-05 | | Release date: | 2020-05-20 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Cryo-EM structure of the human cohesin-NIPBL-DNA complex.
Science, 368, 2020
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6WG4
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6WSL
 | | Cryo-EM structure of VASH1-SVBP bound to microtubules | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, Small vasohibin-binding protein, ... | | Authors: | Li, F, Li, Y, Yu, H. | | Deposit date: | 2020-05-01 | | Release date: | 2020-08-26 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Cryo-EM structure of VASH1-SVBP bound to microtubules.
Elife, 9, 2020
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6BNT
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6WG6
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5T8V
 | | Chaetomium thermophilum cohesin loader SCC2, C-terminal fragment | | Descriptor: | CITRIC ACID, Putative uncharacterized protein | | Authors: | Tomchick, D.R, Yu, H, Kikuchi, S, Ouyang, Z, Borek, D, Otwinowski, Z. | | Deposit date: | 2016-09-08 | | Release date: | 2016-10-19 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.798 Å) | | Cite: | Crystal structure of the cohesin loader Scc2 and insight into cohesinopathy.
Proc.Natl.Acad.Sci.USA, 113, 2016
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4K6J
 | | Human cohesin inhibitor WapL | | Descriptor: | ACETATE ION, SULFATE ION, Wings apart-like protein homolog | | Authors: | Tomchick, D.R, Yu, H, Ouyang, Z. | | Deposit date: | 2013-04-16 | | Release date: | 2013-06-19 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.6205 Å) | | Cite: | Structure of the human cohesin inhibitor Wapl.
Proc.Natl.Acad.Sci.USA, 110, 2013
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3SHU
 | | Crystal structure of ZO-1 PDZ3 | | Descriptor: | Tight junction protein ZO-1 | | Authors: | Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. | | Deposit date: | 2011-06-17 | | Release date: | 2011-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
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3SHW
 | | Crystal structure of ZO-1 PDZ3-SH3-Guk supramodule complex with Connexin-45 peptide | | Descriptor: | Gap junction gamma-1 protein, Tight junction protein ZO-1 | | Authors: | Yu, J, Pan, L, Chen, J, Yu, H, Zhang, M. | | Deposit date: | 2011-06-17 | | Release date: | 2011-09-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The Structure of the PDZ3-SH3-GuK Tandem of ZO-1 Suggests a Supramodular Organization of the Conserved MAGUK Family Scaffold Core
To be Published
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3GMH
 | | Crystal Structure of the Mad2 Dimer | | Descriptor: | Mitotic spindle assembly checkpoint protein MAD2A, SULFATE ION | | Authors: | Ozkan, E, Luo, X, Machius, M, Yu, H, Deisenhofer, J. | | Deposit date: | 2009-03-13 | | Release date: | 2010-11-17 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (3.95 Å) | | Cite: | Structure of an intermediate conformer of the spindle checkpoint protein Mad2.
Proc.Natl.Acad.Sci.USA, 112, 2015
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1DUJ
 | | SOLUTION STRUCTURE OF THE SPINDLE ASSEMBLY CHECKPOINT PROTEIN HUMAN MAD2 | | Descriptor: | SPINDLE ASSEMBLY CHECKPOINT PROTEIN | | Authors: | Luo, X, Fang, G, Coldiron, M, Lin, Y, Yu, H. | | Deposit date: | 2000-01-17 | | Release date: | 2000-03-08 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Structure of the Mad2 spindle assembly checkpoint protein and its interaction with Cdc20.
Nat.Struct.Biol., 7, 2000
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5UN0
 | | Crystal Structure of Mycobacterium Tuberculosis Proteasome-assembly chaperone homologue Rv2125 | | Descriptor: | proteasome assembly chaperone 2 (PAC2) homologue Rv2125 | | Authors: | Bai, L, Jastrab, J.B, Hu, K, Yu, H, Darwin, K.H, Li, H. | | Deposit date: | 2017-01-30 | | Release date: | 2017-03-01 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural Analysis of Mycobacterium tuberculosis Homologues of the Eukaryotic Proteasome Assembly Chaperone 2 (PAC2).
J. Bacteriol., 199, 2017
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3Q6S
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6OCF
 | | The crystal structure of VASH1-SVBP complex | | Descriptor: | CHLORIDE ION, GLYCEROL, Small vasohibin-binding protein, ... | | Authors: | Li, F, Luo, X, Yu, H. | | Deposit date: | 2019-03-23 | | Release date: | 2019-06-26 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (2.102 Å) | | Cite: | Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
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6OCH
 | | Crystal structure of VASH1-SVBP complex bound with parthenolide | | Descriptor: | GLYCEROL, SULFATE ION, Small vasohibin-binding protein, ... | | Authors: | Li, F, Luo, X, Yu, H. | | Deposit date: | 2019-03-23 | | Release date: | 2019-06-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.003 Å) | | Cite: | Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
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4FTW
 | | Crystal structure of a carboxyl esterase N110C/L145H at 2.3 angstrom resolution | | Descriptor: | 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, CHLORIDE ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ... | | Authors: | Wu, L, Ma, J, Zhou, J, Yu, H. | | Deposit date: | 2012-06-28 | | Release date: | 2012-10-03 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
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1KLQ
 | | The Mad2 Spindle Checkpoint Protein Undergoes Similar Major Conformational Changes upon Binding to Either Mad1 or Cdc20 | | Descriptor: | MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD2A, Mad2-binding peptide | | Authors: | Luo, X, Tang, Z, Rizo, J, Yu, H. | | Deposit date: | 2001-12-12 | | Release date: | 2002-01-25 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20.
Mol.Cell, 9, 2002
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3DWA
 | | Crystal structure of the B-subunit of the AB5 toxin from E. coli | | Descriptor: | PENTAETHYLENE GLYCOL, Subtilase cytotoxin, subunit B | | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | Deposit date: | 2008-07-22 | | Release date: | 2008-11-04 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.084 Å) | | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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3DWP
 | | Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc | | Descriptor: | N-glycolyl-alpha-neuraminic acid, PENTAETHYLENE GLYCOL, Subtilase cytotoxin, ... | | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | Deposit date: | 2008-07-22 | | Release date: | 2008-11-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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3DWQ
 | | Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc | | Descriptor: | AZIDE ION, N-PROPANOL, N-glycolyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-galactopyranose, ... | | Authors: | Byres, E, Paton, A.W, Paton, J.C, Lofling, J.C, Smith, D.F, Wilce, M.C.J, Talbot, U.M, Chong, D.C, Yu, H, Huang, S, Chen, X, Varki, N.M, Varki, A, Rossjohn, J, Beddoe, T. | | Deposit date: | 2008-07-22 | | Release date: | 2008-11-04 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Nature, 456, 2008
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6OCG
 | | Crystal structure of VASH1-SVBP complex bound with EpoY | | Descriptor: | CHLORIDE ION, GLYCEROL, N-[(3R)-4-ethoxy-3-hydroxy-4-oxobutanoyl]-L-tyrosine, ... | | Authors: | Li, F, Luo, X, Yu, H. | | Deposit date: | 2019-03-23 | | Release date: | 2019-06-26 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (1.833 Å) | | Cite: | Structural basis of tubulin detyrosination by vasohibins.
Nat.Struct.Mol.Biol., 26, 2019
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6MDX
 | | Mechanism of protease dependent DPC repair | | Descriptor: | 1,2-ETHANEDIOL, CITRATE ANION, DNA (5'-D(P*CP*C)-3'), ... | | Authors: | Li, F, Raczynska, J, Chen, Z, Yu, H. | | Deposit date: | 2018-09-05 | | Release date: | 2019-04-10 | | Last modified: | 2019-12-18 | | Method: | X-RAY DIFFRACTION (1.55 Å) | | Cite: | Structural Insight into DNA-Dependent Activation of Human Metalloprotease Spartan.
Cell Rep, 26, 2019
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4PJW
 | | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion protein 1 (Scc1), with bound MES | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cohesin subunit SA-2, Double-strand-break repair protein rad21 homolog | | Authors: | Hara, K, Chen, Z, Tomchick, D.R, Yu, H. | | Deposit date: | 2014-05-12 | | Release date: | 2014-08-27 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure of cohesin subcomplex pinpoints direct shugoshin-Wapl antagonism in centromeric cohesion.
Nat.Struct.Mol.Biol., 21, 2014
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