8ESB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8esb by Molmil](/molmil-images/mine/8esb) | |
8ESA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8esa by Molmil](/molmil-images/mine/8esa) | |
8ES7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8es7 by Molmil](/molmil-images/mine/8es7) | CryoEM structure of PN45545 TCR-CD3 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | Authors: | Saotome, K, Franklin, M.C. | Deposit date: | 2022-10-13 | Release date: | 2023-05-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
|
|
8ES9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8es9 by Molmil](/molmil-images/mine/8es9) | CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | Authors: | Saotome, K, Franklin, M.C. | Deposit date: | 2022-10-13 | Release date: | 2023-05-03 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM. Nat Commun, 14, 2023
|
|
8ES8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8es8 by Molmil](/molmil-images/mine/8es8) | |
6NF6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nf6 by Molmil](/molmil-images/mine/6nf6) | Structure of chicken Otop3 in nanodiscs | Descriptor: | CHOLESTEROL HEMISUCCINATE, Otopetrin3 | Authors: | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | Deposit date: | 2018-12-18 | Release date: | 2019-06-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.32 Å) | Cite: | Structures of the otopetrin proton channels Otop1 and Otop3. Nat.Struct.Mol.Biol., 26, 2019
|
|
6NF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6nf4 by Molmil](/molmil-images/mine/6nf4) | Structure of zebrafish Otop1 in nanodiscs | Descriptor: | CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, Otopetrin1 | Authors: | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | Deposit date: | 2018-12-18 | Release date: | 2019-06-05 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (2.98 Å) | Cite: | Structures of the otopetrin proton channels Otop1 and Otop3. Nat.Struct.Mol.Biol., 26, 2019
|
|
5IWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iwt by Molmil](/molmil-images/mine/5iwt) | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6 | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2016-03-22 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal structure of the epithelial calcium channel TRPV6. Nature, 534, 2016
|
|
5IWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iwk by Molmil](/molmil-images/mine/5iwk) | Structure of Transient Receptor Potential (TRP) channel TRPV6 | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2016-03-22 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.247 Å) | Cite: | Crystal structure of the epithelial calcium channel TRPV6. Nature, 534, 2016
|
|
5IWP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iwp by Molmil](/molmil-images/mine/5iwp) | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2016-03-22 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Crystal structure of the epithelial calcium channel TRPV6. Nature, 534, 2016
|
|
5IWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5iwr by Molmil](/molmil-images/mine/5iwr) | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of barium | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, BARIUM ION, Transient receptor potential cation channel subfamily V member 6 | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | Deposit date: | 2016-03-22 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3.85 Å) | Cite: | Crystal structure of the epithelial calcium channel TRPV6. Nature, 534, 2016
|
|
8FJB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fjb by Molmil](/molmil-images/mine/8fjb) | |
8FJA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fja by Molmil](/molmil-images/mine/8fja) | |
8U4N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4n by Molmil](/molmil-images/mine/8u4n) | Structure of Apo CXCR4/Gi complex | Descriptor: | C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Saotome, K, McGoldrick, L.L, Franklin, M.C. | Deposit date: | 2023-09-11 | Release date: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024
|
|
8U4R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4r by Molmil](/molmil-images/mine/8u4r) | |
8U4T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4t by Molmil](/molmil-images/mine/8u4t) | |
8U4P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4p by Molmil](/molmil-images/mine/8u4p) | |
8U4O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4o by Molmil](/molmil-images/mine/8u4o) | |
8U4S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4s by Molmil](/molmil-images/mine/8u4s) | |
8U4Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u4q by Molmil](/molmil-images/mine/8u4q) | |
6BPZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6bpz by Molmil](/molmil-images/mine/6bpz) | Structure of the mechanically activated ion channel Piezo1 | Descriptor: | Piezo-type mechanosensitive ion channel component 1,Piezo-type mechanosensitive ion channel component 1,mouse Piezo1,Piezo-type mechanosensitive ion channel component 1,Piezo-type mechanosensitive ion channel component 1 | Authors: | Saotome, K, Kefauver, J.M, Patapoutian, A, Ward, A.B. | Deposit date: | 2017-11-27 | Release date: | 2017-12-27 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the mechanically activated ion channel Piezo1. Nature, 554, 2018
|
|
6XDG
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6xdg by Molmil](/molmil-images/mine/6xdg) | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of two neutralizing antibodies | Descriptor: | REGN10933 antibody Fab fragment heavy chain, REGN10933 antibody Fab fragment light chain, REGN10987 antibody Fab fragment heavy chain, ... | Authors: | Franklin, M.C, Saotome, K, Romero Hernandez, A, Zhou, Y. | Deposit date: | 2020-06-10 | Release date: | 2020-06-24 | Last modified: | 2021-01-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science, 369, 2020
|
|
7M42
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7m42 by Molmil](/molmil-images/mine/7m42) | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of neutralizing antibodies REGN10985 and REGN10989 | Descriptor: | REGN10985 antibody Fab fragment heavy chain, REGN10985 antibody Fab fragment light chain, REGN10989 antibody Fab fragment heavy chain, ... | Authors: | Zhou, Y, Romero Hernandez, A, Saotome, K, Franklin, M.C. | Deposit date: | 2021-03-19 | Release date: | 2021-07-28 | Last modified: | 2021-08-25 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | The monoclonal antibody combination REGEN-COV protects against SARS-CoV-2 mutational escape in preclinical and human studies. Cell, 184, 2021
|
|
6D7O
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d7o by Molmil](/molmil-images/mine/6d7o) | Crystal Structure of Rat TRPV6* in complex with 2-Aminoethoxydiphenyl borate (2-APB) | Descriptor: | 2-aminoethyl diphenylborinate, 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, ... | Authors: | Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I. | Deposit date: | 2018-04-25 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.45 Å) | Cite: | Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB. Nat Commun, 9, 2018
|
|
6D7T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6d7t by Molmil](/molmil-images/mine/6d7t) | Cryo-EM structure of human TRPV6-Y467A in complex with 2-Aminoethoxydiphenyl borate (2-APB) | Descriptor: | 2-aminoethyl diphenylborinate, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | Authors: | Singh, A.K, Saotome, K, McGoldrick, L.L, Sobolevsky, A.I. | Deposit date: | 2018-04-25 | Release date: | 2018-07-18 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (4.44 Å) | Cite: | Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB. Nat Commun, 9, 2018
|
|