8U4T
Structure of tetrameric CXCR4 in complex with REGN7663 Fab
This is a non-PDB format compatible entry.
Summary for 8U4T
Entry DOI | 10.2210/pdb8u4t/pdb |
EMDB information | 41888 41889 41890 41891 41892 41893 41894 |
Descriptor | REGN7663 Fab light chain, REGN7663 Fab heavy chain, C-X-C chemokine receptor type 4, ... (5 entities in total) |
Functional Keywords | gpcr, chemokine receptor, tetramer, oligomer, antibody, signaling protein-immune system complex, signaling protein/immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 493083.97 |
Authors | |
Primary citation | Saotome, K.,McGoldrick, L.L.,Ho, J.,Ramlall, T.,Shah, S.,Moore, M.J.,Kim, J.H.,Leidich, R.,Olson, W.C.,Franklin, M.C. Structural insights into CXCR4 modulation and oligomerization Biorxiv, 2024 Cited by DOI: 10.1101/2024.02.09.579708PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.38 Å) |
Structure validation
Download full validation report