Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
5GR7
DownloadVisualize
BU of 5gr7 by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-1
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
Deposit date:2016-08-08
Release date:2017-06-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5GSB
DownloadVisualize
BU of 5gsb by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 37-3
Descriptor: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-D alpha chain, ...
Authors:Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
Deposit date:2016-08-15
Release date:2017-07-12
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (1.801 Å)
Cite:Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
6LR6
DownloadVisualize
BU of 6lr6 by Molmil
The crystal structure of human cytoplasmic LRS
Descriptor: 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ...
Authors:Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D.
Deposit date:2020-01-15
Release date:2020-03-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3.009 Å)
Cite:Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
5WSH
DownloadVisualize
BU of 5wsh by Molmil
Structure of HLA-A2 P130
Descriptor: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, GLY-VAL-TRP-ILE-ARG-THR-PRO-THR-ALA, ...
Authors:Zhang, Y, Wu, Y, Qi, J, Liu, J, Gao, G.F, Meng, S.
Deposit date:2016-12-07
Release date:2017-12-20
Last modified:2019-01-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:CD8+T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress.
J. Virol., 92, 2018
6PIB
DownloadVisualize
BU of 6pib by Molmil
Structure of the Klebsiella pneumoniae LpxH-AZ1 complex
Descriptor: 1-[5-({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one, MANGANESE (II) ION, TETRAETHYLENE GLYCOL, ...
Authors:Cho, J, Zhou, P.
Deposit date:2019-06-26
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PH9
DownloadVisualize
BU of 6ph9 by Molmil
Crystal Structure of the Klebsiella pneumoniae LpxH-lipid X complex
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Cho, J, Zhou, P.
Deposit date:2019-06-25
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PJ3
DownloadVisualize
BU of 6pj3 by Molmil
Crystal structure of the Klebsiella pneumoniae LpxH/JH-LPH-33 complex
Descriptor: 1,2-ETHANEDIOL, 1-[5-({4-[3-chloro-5-(trifluoromethyl)phenyl]piperazin-1-yl}sulfonyl)-2,3-dihydro-1H-indol-1-yl]ethan-1-one, MANGANESE (II) ION, ...
Authors:Cho, J, Zhou, P.
Deposit date:2019-06-27
Release date:2020-02-12
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis of the UDP-diacylglucosamine pyrophosphohydrolase LpxH inhibition by sulfonyl piperazine antibiotics.
Proc.Natl.Acad.Sci.USA, 117, 2020
8KHC
DownloadVisualize
BU of 8khc by Molmil
SARS-CoV-2 Omicron spike in complex with 5817 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817 Fab, ...
Authors:Cao, L, Wang, X.
Deposit date:2023-08-21
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
8KHD
DownloadVisualize
BU of 8khd by Molmil
The interface structure of Omicron RBD binding to 5817 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of 5817, Light chain of 5817, ...
Authors:Cao, L, Wang, X.
Deposit date:2023-08-21
Release date:2024-04-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Identification of a broad sarbecovirus neutralizing antibody targeting a conserved epitope on the receptor-binding domain.
Cell Rep, 43, 2024
7UO1
DownloadVisualize
BU of 7uo1 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, E.coli RNase P RNA, Precursor tRNA substrate U(-1) and A(-2), ...
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO5
DownloadVisualize
BU of 7uo5 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, RNase P RNA, Ribonuclease P protein component
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO0
DownloadVisualize
BU of 7uo0 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: CALCIUM ION, Precursor tRNA substrate G(-1) G(-2), RNase P RNA, ...
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
7UO2
DownloadVisualize
BU of 7uo2 by Molmil
E.coli RNaseP Holoenzyme with Mg2+
Descriptor: MAGNESIUM ION, RNase P RNA, Ribonuclease P protein component
Authors:Huang, W, Taylor, D.J.
Deposit date:2022-04-12
Release date:2022-09-28
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural and mechanistic basis for recognition of alternative tRNA precursor substrates by bacterial ribonuclease P.
Nat Commun, 13, 2022
6SJ7
DownloadVisualize
BU of 6sj7 by Molmil
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to RBM39 and Indisulam
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1, ...
Authors:Srinivas, H.
Deposit date:2019-08-12
Release date:2019-12-18
Last modified:2019-12-25
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
6UD7
DownloadVisualize
BU of 6ud7 by Molmil
Crystal structure of full-length human DCAF15-DDB1(deltaBPB)-DDA1-RBM39 in complex with indisulam
Descriptor: DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1,DNA damage-binding protein 1, ...
Authors:Bussiere, D.E, Shu, W, Xie, L, Knapp, M.
Deposit date:2019-09-18
Release date:2019-12-18
Last modified:2020-01-22
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
5JLY
DownloadVisualize
BU of 5jly by Molmil
Structure of Peroxiredoxin-1 from Schistosoma japonicum
Descriptor: Thioredoxin peroxidase-1
Authors:Wu, Q, Huang, F, Zeng, D, Liu, X, Zhao, J, Wang, H, Peng, Y, Li, P, Li, Y.
Deposit date:2016-04-27
Release date:2017-05-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.051 Å)
Cite:Crystal structure of Peroxiredoxin-1 from Schistosoma japonicum
To Be Published
5K8K
DownloadVisualize
BU of 5k8k by Molmil
Structure of the Haemophilus influenzae LpxH-lipid X complex
Descriptor: (R)-((2R,3S,4R,5R,6R)-3-HYDROXY-2-(HYDROXYMETHYL)-5-((R)-3-HYDROXYTETRADECANAMIDO)-6-(PHOSPHONOOXY)TETRAHYDRO-2H-PYRAN-4-YL) 3-HYDROXYTETRADECANOATE, ACETATE ION, GLYCEROL, ...
Authors:Cho, J, Lee, C.-J, Zhou, P.
Deposit date:2016-05-30
Release date:2016-08-10
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure of the essential Haemophilus influenzae UDP-diacylglucosamine pyrophosphohydrolase LpxH in lipid A biosynthesis.
Nat Microbiol, 1, 2016
7MK3
DownloadVisualize
BU of 7mk3 by Molmil
Crystal structure of NPR1
Descriptor: CHLORIDE ION, GLYCEROL, Regulatory protein NPR1, ...
Authors:Cheng, J, Wu, Q, Zhou, P.
Deposit date:2021-04-21
Release date:2022-03-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
7MCE
DownloadVisualize
BU of 7mce by Molmil
CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH 2-{(7P)-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl}propan-2-ol
Descriptor: 2-{(7P)-7-(1,4-dimethyl-1H-1,2,3-triazol-5-yl)-8-fluoro-5-[(S)-(oxan-4-yl)(phenyl)methyl]-5H-pyrido[3,2-b]indol-3-yl}propan-2-ol, Bromodomain-containing protein 4
Authors:Sheriff, S.
Deposit date:2021-04-02
Release date:2021-09-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:Development of BET inhibitors as potential treatments for cancer: A new carboline chemotype.
Bioorg.Med.Chem.Lett., 51, 2021
7MK2
DownloadVisualize
BU of 7mk2 by Molmil
CryoEM Structure of NPR1
Descriptor: Regulatory protein NPR1, ZINC ION
Authors:Kumar, S, Zhou, Y, Dillard, L, Borgnia, M, Bartesaghi, A, Zhou, P.
Deposit date:2021-04-21
Release date:2022-03-16
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural basis of NPR1 in activating plant immunity.
Nature, 605, 2022
7KDT
DownloadVisualize
BU of 7kdt by Molmil
Human Tom70 in complex with SARS CoV2 Orf9b
Descriptor: Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2024-03-06
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 370, 2020
6UE5
DownloadVisualize
BU of 6ue5 by Molmil
Crystal structure of full-length human DCAF15-DDB1-deltaPBP-DDA1-RBM39 in complex with 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
Descriptor: 4-(aminomethyl)-N-(3-cyano-4-methyl-1H-indol-7-yl)benzene-1-sulfonamide, DDB1- and CUL4-associated factor 15, DET1- and DDB1-associated protein 1, ...
Authors:Knapp, M.S, Shu, W, Xie, L, Bussiere, D.E.
Deposit date:2019-09-20
Release date:2019-12-18
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex.
Nat.Chem.Biol., 16, 2020
3GYN
DownloadVisualize
BU of 3gyn by Molmil
Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydropyridinone inhibitor
Descriptor: N-{3-[(5R)-1-cyclopentyl-4-hydroxy-5-methyl-5-(3-methylbutyl)-2-oxo-1,2,5,6-tetrahydropyridin-3-yl]-1,1-dioxido-4H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase
Authors:Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R.
Deposit date:2009-04-04
Release date:2009-12-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg.Med.Chem.Lett., 19, 2009
3IGV
DownloadVisualize
BU of 3igv by Molmil
Crystal structure of HCV NS5B polymerase with a novel monocyclic dihydro-pyridinone inhibitor
Descriptor: N-{3-[(6S)-6-ethyl-1-(4-fluorobenzyl)-4-hydroxy-2-oxo-1,2,5,6-tetrahydropyridin-3-yl]-1,1-dioxido-2H-1,2,4-benzothiadiazin-7-yl}methanesulfonamide, RNA-DIRECTED RNA POLYMERASE
Authors:Zhao, Q, Showalter, R.E, Han, Q, Kissinger, C.R.
Deposit date:2009-07-28
Release date:2009-12-08
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Bioorg.Med.Chem.Lett., 19, 2009
6WJC
DownloadVisualize
BU of 6wjc by Molmil
Muscarinic acetylcholine receptor 1 - muscarinic toxin 7 complex
Descriptor: (1R,5S)-8-METHYL-8-AZABICYCLO[3.2.1]OCT-3-YL (2R)-3-HYDROXY-2-PHENYLPROPANOATE, ACETAMIDE, CHOLESTEROL HEMISUCCINATE, ...
Authors:Maeda, S, Kobilka, B.K.
Deposit date:2020-04-13
Release date:2020-07-08
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structure and selectivity engineering of the M1muscarinic receptor toxin complex.
Science, 369, 2020

221051

数据于2024-06-12公开中

PDB statisticsPDBj update infoContact PDBjnumon