Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5DRO

Structure of the Aquifex aeolicus LpxC/LPC-011 Complex

Summary for 5DRO
Entry DOI10.2210/pdb5dro/pdb
Related5DRP 5DRQ 5DRR
DescriptorUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase, ZINC ION, 4-[4-(4-aminophenyl)buta-1,3-diyn-1-yl]-N-[(2S,3R)-3-hydroxy-1-(hydroxyamino)-1-oxobutan-2-yl]benzamide, ... (6 entities in total)
Functional Keywordslpxc, inhibitor, lipid a, gram-negative bacteria, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological sourceAquifex aeolicus (strain VF5)
Total number of polymer chains2
Total formula weight63730.64
Authors
Lee, C.-J.,Najeeb, J.,Zhou, P. (deposition date: 2015-09-16, release date: 2016-03-09, Last modification date: 2023-09-27)
Primary citationLee, C.J.,Liang, X.,Wu, Q.,Najeeb, J.,Zhao, J.,Gopalaswamy, R.,Titecat, M.,Sebbane, F.,Lemaitre, N.,Toone, E.J.,Zhou, P.
Drug design from the cryptic inhibitor envelope.
Nat Commun, 7:10638-10638, 2016
Cited by
PubMed: 26912110
DOI: 10.1038/ncomms10638
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.01 Å)
Structure validation

217705

PDB entries from 2024-03-27

PDB statisticsPDBj update infoContact PDBjnumon