8HPD
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![BU of 8hpd by Molmil](/molmil-images/mine/8hpd) | Bry-LHCII heterotrimer of Bryopsis corticulans | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHLOROPHYLL A, ... | Authors: | Li, Z.H, Shen, J.R, Wang, W.D. | Deposit date: | 2022-12-12 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (2.74 Å) | Cite: | Structural and functional properties of different types of siphonous LHCII trimers from an intertidal green alga Bryopsis corticulans. Structure, 31, 2023
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8HLV
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![BU of 8hlv by Molmil](/molmil-images/mine/8hlv) | Bry-LHCII homotrimer of Bryopsis corticulans | Descriptor: | (1R,3R)-6-{(3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4R,6R)-4-HYDROXY-2,2,6-TRIMETHYL-7-OXABICYCLO[4.1.0]HEPT-1-YL]-3,7,12,16-TETRAMETHYLOCTADECA-1,3,5,7,9,11,13,15,17-NONAENYLIDENE}-1,5,5-TRIMETHYLCYCLOHEXANE-1,3-DIOL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, CHLOROPHYLL A, ... | Authors: | Li, Z.H, Shen, J.R, Wang, W.D. | Deposit date: | 2022-12-01 | Release date: | 2023-09-06 | Last modified: | 2023-10-18 | Method: | ELECTRON MICROSCOPY (2.55 Å) | Cite: | Structural and functional properties of different types of siphonous LHCII trimers from an intertidal green alga Bryopsis corticulans. Structure, 31, 2023
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5XS4
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![BU of 5xs4 by Molmil](/molmil-images/mine/5xs4) | Structure of Coxsackievirus A6 (CVA6) virus A-particle | Descriptor: | Genome polyprotein | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T. | Deposit date: | 2017-06-12 | Release date: | 2017-09-27 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody Nat Commun, 8, 2017
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6NYH
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![BU of 6nyh by Molmil](/molmil-images/mine/6nyh) | Structure of human RIPK1 kinase domain in complex with GNE684 | Descriptor: | (5S)-N-[(3S)-7-methoxy-1-methyl-2-oxo-2,3,4,5-tetrahydro-1H-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide, IODIDE ION, Receptor-interacting serine/threonine-protein kinase 1 | Authors: | Fong, R, Lupardus, P.J. | Deposit date: | 2019-02-11 | Release date: | 2019-05-29 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases. Cell Death Differ., 27, 2020
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5XJZ
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![BU of 5xjz by Molmil](/molmil-images/mine/5xjz) | Structure of DNA1-Ag complex | Descriptor: | DNA (5'-D(*GP*CP*AP*CP*GP*CP*GP*C)-3'), SILVER ION, SPERMINE | Authors: | Liu, H.H, Gan, J.H. | Deposit date: | 2017-05-04 | Release date: | 2017-12-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs Angew. Chem. Int. Ed. Engl., 56, 2017
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6O44
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![BU of 6o44 by Molmil](/molmil-images/mine/6o44) | Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, Nattokinase, ... | Authors: | Tang, H, Shi, K, Aihara, H. | Deposit date: | 2019-02-28 | Release date: | 2019-04-10 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Insight into subtilisin E-S7 cleavage pattern based on crystal structure and hydrolysates peptide analysis. Biochem. Biophys. Res. Commun., 512, 2019
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7Y3G
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![BU of 7y3g by Molmil](/molmil-images/mine/7y3g) | Cryo-EM structure of a class A orphan GPCR | Descriptor: | G-protein coupled receptor 12, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, Z.J, Hua, T, Li, H, Zhang, J.Y, Luo, F. | Deposit date: | 2022-06-10 | Release date: | 2023-06-07 | Method: | ELECTRON MICROSCOPY (2.77 Å) | Cite: | Structural insight into the constitutive activity of human orphan receptor GPR12. Sci Bull (Beijing), 68, 2023
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5VKZ
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![BU of 5vkz by Molmil](/molmil-images/mine/5vkz) | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies | Descriptor: | Mitochondrial distribution and morphology protein 12 | Authors: | Egea, P.F, AhYoung, A.P, Lu, B, Tan, H.R, Cascio, D. | Deposit date: | 2017-04-24 | Release date: | 2017-07-05 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (4.1 Å) | Cite: | Crystal structure of Mdm12 and combinatorial reconstitution of Mdm12/Mmm1 ERMES complexes for structural studies. Biochem. Biophys. Res. Commun., 488, 2017
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4LWV
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![BU of 4lwv by Molmil](/molmil-images/mine/4lwv) | The 2.3A Crystal Structure of Humanized Xenopus MDM2 with RO5545353 | Descriptor: | (2S,3R,4R,5R)-N-(4-carbamoyl-2-methoxyphenyl)-2'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-5'-oxo-4',5'-dihydrospiro[pyrrolidine-3,6'-thieno[3,2-b]pyrrole]-5-carboxamide, E3 ubiquitin-protein ligase Mdm2, SULFATE ION | Authors: | Graves, B.J, Lukacs, C, Janson, C.A. | Deposit date: | 2013-07-28 | Release date: | 2014-07-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.32 Å) | Cite: | Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development. ACS MED.CHEM.LETT., 5, 2014
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5XEG
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![BU of 5xeg by Molmil](/molmil-images/mine/5xeg) | The structure of OsALKBH1 | Descriptor: | 2-OXOGLUTARIC ACID, MANGANESE (II) ION, Oxidoreductase, ... | Authors: | Wang, C, Guo, Y, Zeng, Z. | Deposit date: | 2017-04-05 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification and analysis of adenine N6-methylation sites in the rice genome. Nat Plants, 4, 2018
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5XS7
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![BU of 5xs7 by Molmil](/molmil-images/mine/5xs7) | Structure of Coxsackievirus A6 (CVA6) virus A-particle in complex with the neutralizing antibody fragment 1D5 | Descriptor: | Genome polyprotein, Heavy chain of Fab 1D5, Light chain of Fab 1D5 | Authors: | Zheng, Q.B, He, M.Z, Xu, L.F, Yu, H, Li, S.W, Cheng, T. | Deposit date: | 2017-06-12 | Release date: | 2017-09-27 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Atomic structures of Coxsackievirus A6 and its complex with a neutralizing antibody Nat Commun, 8, 2017
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6A85
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![BU of 6a85 by Molmil](/molmil-images/mine/6a85) | Crystal structure of a novel DNA quadruplex | Descriptor: | AMMONIUM ION, DNA (5'-D(*AP*GP*AP*GP*AP*GP*AP*TP*GP*GP*GP*TP*GP*CP*GP*TP*T)-3'), LEAD (II) ION, ... | Authors: | Liu, H.H, Gan, J.H. | Deposit date: | 2018-07-06 | Release date: | 2019-03-06 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | High-resolution DNA quadruplex structure containing all the A-, G-, C-, T-tetrads. Nucleic Acids Res., 46, 2018
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7YIM
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![BU of 7yim by Molmil](/molmil-images/mine/7yim) | Cryo-EM structure of human Alpha-fetoprotein | Descriptor: | Alpha-fetoprotein | Authors: | Liu, N, Liu, K, Wu, C, Liu, Z, Li, M, Wang, J, Wang, H.W. | Deposit date: | 2022-07-17 | Release date: | 2023-01-18 | Last modified: | 2023-01-25 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Uniform thin ice on ultraflat graphene for high-resolution cryo-EM. Nat.Methods, 20, 2023
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5XOI
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![BU of 5xoi by Molmil](/molmil-images/mine/5xoi) | The structure of OsALKBH1 | Descriptor: | MANGANESE (II) ION, Oxidoreductase, 2OG-Fe oxygenase family protein, ... | Authors: | Wang, C, Guo, Y, Zeng, Z. | Deposit date: | 2017-05-28 | Release date: | 2018-06-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Identification and analysis of adenine N6-methylation sites in the rice genome. Nat Plants, 4, 2018
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5XK1
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![BU of 5xk1 by Molmil](/molmil-images/mine/5xk1) | Structure of 8-mer DNA3 | Descriptor: | DNA (5'-D(*GP*GP*AP*GP*CP*CP*CP*C)-3') | Authors: | Liu, H.H, Gan, J.H. | Deposit date: | 2017-05-04 | Release date: | 2017-12-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.501 Å) | Cite: | A DNA Structure Containing AgI -Mediated G:G and C:C Base Pairs. Angew. Chem. Int. Ed. Engl., 56, 2017
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7YLM
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![BU of 7ylm by Molmil](/molmil-images/mine/7ylm) | Cryo-EM structure of 8-subunit Smc5/6 hinge region | Descriptor: | MMS21 isoform 1, SMC6 isoform 1, Structural maintenance of chromosomes protein 5 | Authors: | Qian, L, Jun, Z, Xiang, Z, Wang, Z, Tong, C, Duo, J, Zhenguo, C, Wang, L. | Deposit date: | 2022-07-26 | Release date: | 2024-01-31 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (6.17 Å) | Cite: | Cryo-EM structures of Smc5/6 in multiple states reveal its assembly and functional mechanisms. Nat.Struct.Mol.Biol., 2024
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5W0T
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![BU of 5w0t by Molmil](/molmil-images/mine/5w0t) | |
2P0X
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![BU of 2p0x by Molmil](/molmil-images/mine/2p0x) | solution structure of a non-biological ATP-binding protein | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, ZINC ION, abiotic ATP-binding, ... | Authors: | Mansy, S.S, Szostak, J.W, Chaput, J.C. | Deposit date: | 2007-03-01 | Release date: | 2007-08-07 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure and Evolutionary Analysis of a Non-biological ATP-binding Protein J.Mol.Biol., 371, 2007
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4NIE
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![BU of 4nie by Molmil](/molmil-images/mine/4nie) | |
3UA0
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![BU of 3ua0 by Molmil](/molmil-images/mine/3ua0) | N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease | Descriptor: | Fibroin heavy chain | Authors: | He, Y.-X, Zhang, N.-N, Chen, B.-Y, Li, W.-F, Chen, Y.-X, Zhou, C.-Z. | Deposit date: | 2011-10-20 | Release date: | 2012-03-28 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | N-Terminal Domain of Bombyx mori Fibroin Mediates the Assembly of Silk in Response to pH Decrease. J.Mol.Biol., 418, 2012
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5DRY
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![BU of 5dry by Molmil](/molmil-images/mine/5dry) | Crystal structure of Dot1L in complex with inhibitor CPD3 [N-(1-(2-chlorophenyl)-1H-indol-6-yl)-2-(2-(5-(2-chlorophenyl)-1H-tetrazol-1-yl)acetyl)hydrazinecarboxamide] | Descriptor: | Histone-lysine N-methyltransferase, H3 lysine-79 specific, N-[1-(2-chlorophenyl)-1H-indol-6-yl]-2-{[5-(2-chlorophenyl)-1H-tetrazol-1-yl]acetyl}hydrazinecarboxamide, ... | Authors: | Scheufler, C, Gaul, C, Be, C, Moebitz, H. | Deposit date: | 2015-09-16 | Release date: | 2016-06-15 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Discovery of Novel Dot1L Inhibitors through a Structure-Based Fragmentation Approach. Acs Med.Chem.Lett., 7, 2016
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5EEG
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![BU of 5eeg by Molmil](/molmil-images/mine/5eeg) | Crystal structure of carminomycin-4-O-methyltransferase DnrK in complex with tetrazole-SAH | Descriptor: | (2~{R},3~{R},4~{S},5~{S})-2-(6-aminopurin-9-yl)-5-[[(3~{S})-3-azanyl-3-(1~{H}-1,2,3,4-tetrazol-5-yl)propyl]sulfanylmethyl]oxolane-3,4-diol, Carminomycin 4-O-methyltransferase DnrK | Authors: | Wang, F, Singh, S, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | Deposit date: | 2015-10-22 | Release date: | 2015-12-23 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.255 Å) | Cite: | Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. Acs Chem.Biol., 11, 2016
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7EBJ
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![BU of 7ebj by Molmil](/molmil-images/mine/7ebj) | Apo structure of the mouse Trim66 PHD-Bromo dual domain | Descriptor: | Tripartite motif-containing protein 66, ZINC ION | Authors: | Wang, Z, Jiang, J. | Deposit date: | 2021-03-09 | Release date: | 2022-03-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A TRIM66/DAX1/Dux axis suppresses the totipotent 2-cell-like state in murine embryonic stem cells. Cell Stem Cell, 29, 2022
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7KOV
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![BU of 7kov by Molmil](/molmil-images/mine/7kov) | |
7L51
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![BU of 7l51 by Molmil](/molmil-images/mine/7l51) | |