7X34
 
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7XC5
 | | Crystal structure of the ANK domain of CLPB | | Descriptor: | Isoform 2 of Caseinolytic peptidase B protein homolog | | Authors: | Liu, Y, Wu, D, Lu, G, Gao, N, Lin, J. | | Deposit date: | 2022-03-23 | | Release date: | 2023-01-18 | | Last modified: | 2024-05-29 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Comprehensive structural characterization of the human AAA+ disaggregase CLPB in the apo- and substrate-bound states reveals a unique mode of action driven by oligomerization.
Plos Biol., 21, 2023
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8YJL
 | | Structure of the human endogenous PCNA-FEN1 complex - State B | | Descriptor: | 5 prime DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-02 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJS
 | | Structure of the human endogenous PCNA-FEN1 complex - State E | | Descriptor: | 5 prime flap DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-02 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJZ
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8YJV
 | | Structure of the human endogenous PCNA-FEN1 complex - State G | | Descriptor: | 5 prime flap DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-03 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJQ
 | | Structure of the human endogenous PCNA-FEN1 complex - State C | | Descriptor: | 5 prime flap DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-02 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJW
 | | Structure of the human endogenous PCNA-FEN1 complex - State H | | Descriptor: | 5 prime flap DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-03 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.55 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJU
 | | Structure of the human endogenous PCNA-FEN1 complex - State F | | Descriptor: | 5 prime flap DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-02 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-16 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJR
 | | Structure of the human endogenous PCNA-FEN1 complex - State D | | Descriptor: | 5 prime flap DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-02 | | Release date: | 2024-12-04 | | Last modified: | 2025-01-29 | | Method: | ELECTRON MICROSCOPY (3.51 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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8YJH
 | | Structure of the human endogenous PCNA-FEN1 complex - State A | | Descriptor: | 5 prime DNA, Flap endonuclease 1, Proliferating cell nuclear antigen, ... | | Authors: | Tian, Y, Gao, N. | | Deposit date: | 2024-03-01 | | Release date: | 2024-12-04 | | Last modified: | 2025-07-23 | | Method: | ELECTRON MICROSCOPY (3.68 Å) | | Cite: | Structural insight into Okazaki fragment maturation mediated by PCNA-bound FEN1 and RNaseH2.
Embo J., 44, 2025
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5XXB
 | | Large subunit of Toxoplasma gondii ribosome | | Descriptor: | 25S RNA, 5.8S RNA, 5S RNA, ... | | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | Deposit date: | 2017-07-03 | | Release date: | 2017-08-30 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.17 Å) | | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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5XXU
 | | Small subunit of Toxoplasma gondii ribosome | | Descriptor: | 18S RNA, Ribosomal protein eL41, Ribosomal protein eS1, ... | | Authors: | LI, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | Deposit date: | 2017-07-05 | | Release date: | 2017-08-30 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.35 Å) | | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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5XY3
 | | Large subunit of Trichomonas vaginalis ribosome | | Descriptor: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | Authors: | Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. | | Deposit date: | 2017-07-06 | | Release date: | 2017-08-30 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii
Cell Res., 27, 2017
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5XYU
 | | Small subunit of Mycobacterium smegmatis ribosome | | Descriptor: | 16S RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | | Authors: | Li, Z, Zhang, Y, Zheng, L, Ge, X, Sanyal, S, Gao, N. | | Deposit date: | 2017-07-10 | | Release date: | 2017-09-27 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.45 Å) | | Cite: | Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
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5XYM
 | | Large subunit of Mycobacterium smegmatis | | Descriptor: | 23S RNA, 50S ribosomal protein L13, 50S ribosomal protein L14, ... | | Authors: | Li, Z, Ge, X, Zhang, Y, Zheng, L, Sanyal, S, Gao, N. | | Deposit date: | 2017-07-09 | | Release date: | 2017-09-27 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.08 Å) | | Cite: | Cryo-EM structure of Mycobacterium smegmatis ribosome reveals two unidentified ribosomal proteins close to the functional centers.
Protein Cell, 9, 2018
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8W8Q
 | | Cryo-EM structure of the GPR101-Gs complex | | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | | Authors: | Sun, J.P, Gao, N, Yu, X, Wang, G.P, Yang, F, Wang, J.Y, Yang, Z, Guan, Y. | | Deposit date: | 2023-09-04 | | Release date: | 2024-01-03 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.89 Å) | | Cite: | Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat.Chem.Biol., 20, 2024
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8W8S
 | | Cryo-EM structure of the AA14-bound GPR101 complex | | Descriptor: | 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Probable G-protein coupled receptor 101 | | Authors: | Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. | | Deposit date: | 2023-09-04 | | Release date: | 2024-01-03 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat.Chem.Biol., 20, 2024
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8W8R
 | | Cryo-EM structure of the AA-14-bound GPR101-Gs complex | | Descriptor: | 1-(4-methylpyridin-2-yl)-3-[3-(trifluoromethyl)phenyl]thiourea, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Sun, J.P, Yu, X, Gao, N, Yang, F, Wang, J.Y, Yang, Z, Guan, Y, Wang, G.P. | | Deposit date: | 2023-09-04 | | Release date: | 2024-01-03 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure of GPR101-Gs enables identification of ligands with rejuvenating potential.
Nat.Chem.Biol., 20, 2024
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8HFQ
 | | Cryo-EM structure of CpcL-PBS from cyanobacterium Synechocystis sp. PCC 6803 | | Descriptor: | C-phycocyanin alpha subunit, C-phycocyanin beta subunit, Ferredoxin--NADP reductase, ... | | Authors: | Zheng, L, Zhang, Z, Wang, H, Zheng, Z, Gao, N, Zhao, J. | | Deposit date: | 2022-11-11 | | Release date: | 2023-11-08 | | Method: | ELECTRON MICROSCOPY (2.64 Å) | | Cite: | Cryo-EM and femtosecond spectroscopic studies provide mechanistic insight into the energy transfer in CpcL-phycobilisomes.
Nat Commun, 14, 2023
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6J0B
 | | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath-tube complex in extended state | | Descriptor: | Pvc1, Pvc2 | | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | | Deposit date: | 2018-12-23 | | Release date: | 2019-04-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
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6J0C
 | | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath complex in contracted state | | Descriptor: | Pvc2 | | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | | Deposit date: | 2018-12-23 | | Release date: | 2019-04-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
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7VHQ
 | | Structural insights into the membrane microdomain organization by SPFH family proteins | | Descriptor: | ATP-dependent zinc metalloprotease FtsH, Modulator of FtsH protease HflC, Protein HflK | | Authors: | Ma, C.Y, Wang, C.K, Luo, D.Y, Yan, L, Yang, W.X, Li, N.N, Gao, N. | | Deposit date: | 2021-09-22 | | Release date: | 2022-01-19 | | Last modified: | 2025-06-25 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural insights into the membrane microdomain organization by SPFH family proteins.
Cell Res., 32, 2022
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6J0F
 | | Cryo-EM Structure of an Extracellular Contractile Injection System, PVC sheath/tube terminator in extended state | | Descriptor: | Pvc1, Pvc16 | | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | | Deposit date: | 2018-12-24 | | Release date: | 2019-04-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
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6J0N
 | | Cryo-EM Structure of an Extracellular Contractile Injection System, baseplate in extended state, refined in C6 symmetry | | Descriptor: | Pvc1, Pvc11, Pvc12, ... | | Authors: | Jiang, F, Li, N, Wang, X, Cheng, J, Huang, Y, Yang, Y, Yang, J, Cai, B, Wang, Y, Jin, Q, Gao, N. | | Deposit date: | 2018-12-25 | | Release date: | 2019-04-10 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Cryo-EM Structure and Assembly of an Extracellular Contractile Injection System.
Cell, 177, 2019
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