7CAT
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![BU of 7cat by Molmil](/molmil-images/mine/7cat) | The NADPH binding site on beef liver catalase | Descriptor: | CATALASE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Murthy, M.R.N, Reid III, T.J, Sicignano, A, Tanaka, N, Fita, I, Rossmann, M.G. | Deposit date: | 1984-11-15 | Release date: | 1985-04-01 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The NADPH binding site on beef liver catalase. Proc.Natl.Acad.Sci.USA, 82, 1985
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5WJX
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![BU of 5wjx by Molmil](/molmil-images/mine/5wjx) | Cryo-EM structure of B. subtilis flagellar filaments S17P | Descriptor: | Flagellin | Authors: | Wang, F, Burrage, A.M, Orlova, A, Kearns, D.B, Egelman, E.H. | Deposit date: | 2017-07-24 | Release date: | 2017-10-25 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (6.7 Å) | Cite: | A structural model of flagellar filament switching across multiple bacterial species. Nat Commun, 8, 2017
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4K55
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![BU of 4k55 by Molmil](/molmil-images/mine/4k55) | |
3M7S
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![BU of 3m7s by Molmil](/molmil-images/mine/3m7s) | Crystal structure of the complex of xylanase GH-11 and alpha amylase inhibitor protein with cellobiose at 2.4 A resolution | Descriptor: | ACETATE ION, Haementhin, PHOSPHATE ION, ... | Authors: | Kumar, S, Dube, D, Singh, N, Sinha, M, Bhushan, A, Kaur, P, Sharma, S, Singh, T.P. | Deposit date: | 2010-03-17 | Release date: | 2010-05-05 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure determination and inhibition studies of a novel xylanase and alpha-amylase inhibitor protein (XAIP) from Scadoxus multiflorus. Febs J., 277, 2010
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3M8R
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![BU of 3m8r by Molmil](/molmil-images/mine/3m8r) | Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in a closed ternary complex with trapped 4'-ethylated dTTP | Descriptor: | 4'-ethylthymidine 5'-(tetrahydrogen triphosphate), ACETATE ION, DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... | Authors: | Diederichs, K, Marx, A, Betz, K. | Deposit date: | 2010-03-19 | Release date: | 2010-07-07 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of DNA polymerases caught processing size-augmented nucleotide probes. Angew.Chem.Int.Ed.Engl., 49, 2010
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5WI8
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![BU of 5wi8 by Molmil](/molmil-images/mine/5wi8) | |
3D8B
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![BU of 3d8b by Molmil](/molmil-images/mine/3d8b) | Crystal structure of human fidgetin-like protein 1 in complex with ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Fidgetin-like protein 1 | Authors: | Karlberg, T, Wisniewska, M, Andersson, J, Arrowsmith, C.H, Berglund, H, Busam, R.D, Collins, R, Dahlgren, L.G, Edwards, A.M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Johansson, A, Johansson, I, Kallas, A, Kotenyova, T, Lehtio, L, Moche, M, Nilsson, M.E, Nordlund, P, Nyman, T, Olesen, K, Persson, C, Sagemark, J, Thorsell, A.G, Tresaugues, L, Van Den Berg, S, Welin, M, Wikstrom, M, Schuler, H, Structural Genomics Consortium (SGC) | Deposit date: | 2008-05-23 | Release date: | 2008-08-26 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Human fidgetin-like protein 1. To be Published
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5WIU
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![BU of 5wiu by Molmil](/molmil-images/mine/5wiu) | Structure of the human D4 Dopamine receptor in complex with Nemonapride | Descriptor: | D(4) dopamine receptor, soluble cytochrome b562 chimera, DI(HYDROXYETHYL)ETHER, ... | Authors: | Wacker, D, Wang, S, Levit, A, Che, T, Betz, R.M, McCorvy, J.D, Venkatakrishnan, A.J, Huang, X.-P, Dror, R.O, Shoichet, B.K, Roth, B.L. | Deposit date: | 2017-07-20 | Release date: | 2017-10-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.962 Å) | Cite: | D4 dopamine receptor high-resolution structures enable the discovery of selective agonists. Science, 358, 2017
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5LCE
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![BU of 5lce by Molmil](/molmil-images/mine/5lce) | Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(5-chloro-2-(hydroxymethyl)benzy l)pyrrolidine-2-carboxamide | Descriptor: | (2~{S})-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]-~{N}-[[5-chloranyl-2-(hydroxymethyl)phenyl]methyl]pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sandner, A, Heine, A, Klebe, G. | Deposit date: | 2016-06-21 | Release date: | 2017-07-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.39 Å) | Cite: | Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019
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5W83
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![BU of 5w83 by Molmil](/molmil-images/mine/5w83) | Rpn8/Rpn11 dimer complex | Descriptor: | 26S proteasome regulatory subunit RPN8, Ubiquitin carboxyl-terminal hydrolase RPN11, ZINC ION | Authors: | Dong, K.C, Worden, E.J, Martin, A. | Deposit date: | 2017-06-21 | Release date: | 2017-09-06 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.554 Å) | Cite: | An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome. Mol. Cell, 67, 2017
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5LL6
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![BU of 5ll6 by Molmil](/molmil-images/mine/5ll6) | Structure of the 40S ABCE1 post-splitting complex in ribosome recycling and translation initiation | Descriptor: | 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... | Authors: | Heuer, A, Gerovac, M, Schmidt, C, Trowitzsch, S, Preis, A, Koetter, P, Berninghausen, O, Becker, T, Beckmann, R, Tampe, R. | Deposit date: | 2016-07-26 | Release date: | 2017-04-12 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the 40S-ABCE1 post-splitting complex in ribosome recycling and translation initiation. Nat. Struct. Mol. Biol., 24, 2017
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4BWL
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![BU of 4bwl by Molmil](/molmil-images/mine/4bwl) | Structure of the Y137A mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate, N-acetyl-D-mannosamine and N- acetylneuraminic acid | Descriptor: | 2-(ACETYLAMINO)-2-DEOXY-D-MANNOSE, 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-2-ulosonic acid, N-ACETYLNEURAMINATE LYASE, ... | Authors: | Campeotto, I, Phillips, S.E.V, Pearson, A.R, Nelson, A, Berry, A. | Deposit date: | 2013-07-03 | Release date: | 2014-02-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The Reaction Mechanism of N-Acetylneuraminic Acid Lyase Revealed by a Combination of Crystallography, Qm/Mm Simulation and Mutagenesis. Acs Chem.Biol., 9, 2014
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11BA
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![BU of 11ba by Molmil](/molmil-images/mine/11ba) | BINDING OF A SUBSTRATE ANALOGUE TO A DOMAIN SWAPPING PROTEIN IN THE COMPLEX OF BOVINE SEMINAL RIBONUCLEASE WITH URIDYLYL-2',5'-ADENOSINE | Descriptor: | PROTEIN (RIBONUCLEASE, SEMINAL), SULFATE ION, ... | Authors: | Vitagliano, L, Adinolfi, S, Riccio, A, Sica, F, Zagari, A, Mazzarella, L. | Deposit date: | 1999-03-17 | Release date: | 1999-03-26 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2',5')adenosine. Protein Sci., 7, 1998
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5WDL
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![BU of 5wdl by Molmil](/molmil-images/mine/5wdl) | A processive dipeptidyl aminopeptidase secreted from an established commensal bacterium P. distasonis | Descriptor: | Aminopeptidase C, N-[(3S)-6-carbamimidamido-2-oxohexan-3-yl]glycinamide, POTASSIUM ION | Authors: | Wolan, D.W, Xu, J.H, Solania, A, Chatterjee, S, Jiang, Z, ODonoghue, A.J. | Deposit date: | 2017-07-05 | Release date: | 2018-07-11 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.625 Å) | Cite: | A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro. Acs Chem.Biol., 13, 2018
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7PEN
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5LPD
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![BU of 5lpd by Molmil](/molmil-images/mine/5lpd) | Thrombin in complex with (S)-1-((R)-2-amino-3-cyclohexylpropanoyl)-N-(2-(aminomethyl)-5-chlorobenzyl) pyrrolidine-2-carboxamide | Descriptor: | (2~{S})-~{N}-[[2-(aminomethyl)-5-chloranyl-phenyl]methyl]-1-[(2~{R})-2-azanyl-3-cyclohexyl-propanoyl]pyrrolidine-2-carboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | Authors: | Sandner, A, Heine, A, Klebe, G. | Deposit date: | 2016-08-12 | Release date: | 2017-07-26 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Strategies for Late-Stage Optimization: Profiling Thermodynamics by Preorganization and Salt Bridge Shielding. J.Med.Chem., 62, 2019
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7PTM
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![BU of 7ptm by Molmil](/molmil-images/mine/7ptm) | Crystal Structure of Two-Domain Laccase mutant M199G/R240H from Streptomyces griseoflavus | Descriptor: | COPPER (II) ION, GLYCEROL, OXYGEN MOLECULE, ... | Authors: | Gabdulkhakov, A, Tishchenko, S, Kolyadenko, I. | Deposit date: | 2021-09-27 | Release date: | 2022-01-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Engineering the Catalytic Properties of Two-Domain Laccase from Streptomyces griseoflavus Ac-993. Int J Mol Sci, 23, 2021
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7PFR
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![BU of 7pfr by Molmil](/molmil-images/mine/7pfr) | |
7PU0
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![BU of 7pu0 by Molmil](/molmil-images/mine/7pu0) | |
7PES
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![BU of 7pes by Molmil](/molmil-images/mine/7pes) | Crystal Structure of Two-Domain Laccase mutant M199G from Streptomyces griseoflavus | Descriptor: | COPPER (II) ION, OXYGEN MOLECULE, SODIUM ION, ... | Authors: | Gabdulkhakov, A, Tishchenko, S, Kolyadenko, I. | Deposit date: | 2021-08-11 | Release date: | 2022-01-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Engineering the Catalytic Properties of Two-Domain Laccase from Streptomyces griseoflavus Ac-993. Int J Mol Sci, 23, 2021
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7PUH
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![BU of 7puh by Molmil](/molmil-images/mine/7puh) | Crystal Structure of Two-Domain Laccase mutant H165A/R240H from Streptomyces griseoflavus | Descriptor: | 1,2-ETHANEDIOL, COPPER (II) ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Kolyadenko, I, Tishchenko, S, Gabdulkhakov, A. | Deposit date: | 2021-09-30 | Release date: | 2022-01-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Engineering the Catalytic Properties of Two-Domain Laccase from Streptomyces griseoflavus Ac-993. Int J Mol Sci, 23, 2021
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4C9X
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![BU of 4c9x by Molmil](/molmil-images/mine/4c9x) | Crystal structure of NUDT1 (MTH1) with S-crizotinib | Descriptor: | 3-[(1S)-1-(2,6-DICHLORO-3-FLUOROPHENYL)ETHOXY]-5-(1-PIPERIDIN-4-YLPYRAZOL-4-YL)PYRIDIN-2-AMINE, 7,8-DIHYDRO-8-OXOGUANINE TRIPHOSPHATASE, CHLORIDE ION, ... | Authors: | Elkins, J.M, Salah, E, Huber, K, Superti-Furga, G, Abdul Azeez, K.R, Krojer, T, von Delft, F, Bountra, C, Edwards, A, Knapp, S. | Deposit date: | 2013-10-03 | Release date: | 2014-04-02 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Stereospecific Targeting of Mth1 by (S)-Crizotinib as an Anticancer Strategy. Nature, 508, 2014
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5WIW
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![BU of 5wiw by Molmil](/molmil-images/mine/5wiw) | |
4CB5
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![BU of 4cb5 by Molmil](/molmil-images/mine/4cb5) | Structure of Influenza A H5N1 PB2 cap-binding domain with bound cap analogue (compound 8f) | Descriptor: | 9-N-(3-CARBOXY-4-HYDROXYPHENYL)KETOMETHYL-7-N-METHYLGUANINE, CHLORIDE ION, POLYMERASE BASIC SUBUNIT 2 | Authors: | Pautus, S, Sehr, P, Lewis, J, Fortune, A, Wolkerstorfer, A, Szolar, O, Gulligay, D, Lunardi, T, Decout, J.L, Cusack, S. | Deposit date: | 2013-10-10 | Release date: | 2013-10-30 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | New 7-Methyl-Guanosine Derivatives Targeting the Influenza Polymerase Pb2 CAP-Binding Domain J.Med.Chem., 56, 2013
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2M2C
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![BU of 2m2c by Molmil](/molmil-images/mine/2m2c) | Solution structure of Duplex DNA | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*TP*AP*GP*CP*AP*TP*GP*CP*GP*C)-3'), DNA (5'-D(*GP*CP*GP*CP*AP*TP*GP*CP*TP*AP*CP*GP*CP*G)-3') | Authors: | Ghosh, A, Kar, R.K, Chatterjee, S, Bhunia, A. | Deposit date: | 2012-12-18 | Release date: | 2013-01-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Indolicidin targets duplex DNA: structural and mechanistic insight through a combination of spectroscopy and microscopy. Chemmedchem, 9, 2014
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