5WDL

A processive dipeptidyl aminopeptidase secreted from an established commensal bacterium P. distasonis

Summary for 5WDL

Entry DOI	10.2210/pdb5wdl/pdb
Descriptor	Aminopeptidase C, N-[(3S)-6-carbamimidamido-2-oxohexan-3-yl]glycinamide, POTASSIUM ION, ... (4 entities in total)
Functional Keywords	protease, hydrolase
Biological source	Parabacteroides distasonis (strain ATCC 8503 / DSM 20701 / CIP 104284 / JCM 5825 / NCTC 11152)
Total number of polymer chains	6
Total formula weight	277217.05
Authors	Wolan, D.W.,Xu, J.H.,Solania, A.,Chatterjee, S.,Jiang, Z.,ODonoghue, A.J. (deposition date: 2017-07-05, release date: 2018-07-11, Last modification date: 2023-10-04)
Primary citation	Xu, J.H.,Jiang, Z.,Solania, A.,Chatterjee, S.,Suzuki, B.,Lietz, C.B.,Hook, V.Y.H.,O'Donoghue, A.J.,Wolan, D.W. A Commensal Dipeptidyl Aminopeptidase with Specificity for N-Terminal Glycine Degrades Human-Produced Antimicrobial Peptides in Vitro. Acs Chem.Biol., 13:2513-2521, 2018 Cited by PubMed: 30085657 DOI: 10.1021/acschembio.8b00420 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.625 Å)

Structure validation