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3D1D
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BU of 3d1d by Molmil
Hexagonal crystal structure of Tas3 C-terminal alpha motif
Descriptor: RNA-induced transcriptional silencing complex protein tas3
Authors:Li, H, Patel, D.J.
Deposit date:2008-05-05
Release date:2009-04-21
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:An alpha motif at Tas3 C terminus mediates RITS cis spreading and promotes heterochromatic gene silencing.
Mol.Cell, 34, 2009
1YTY
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BU of 1yty by Molmil
Structural basis for recognition of UUUOH 3'-terminii of nascent RNA pol III transcripts by La autoantigen
Descriptor: 5'-R(*UP*GP*CP*UP*GP*UP*UP*UP*U)-3', Lupus La protein
Authors:Teplova, M, Yuan, Y.R, Ilin, S, Malinina, L, Phan, A.T, Teplov, A, Patel, D.J.
Deposit date:2005-02-11
Release date:2006-01-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.29 Å)
Cite:Structural Basis for Recognition and Sequestration of UUU(OH) 3' Temini of Nascent RNA Polymerase III Transcripts by La, a Rheumatic Disease Autoantigen.
Mol.Cell, 21, 2006
1YTU
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BU of 1ytu by Molmil
Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI protein
Descriptor: 5'-R(P*AP*GP*AP*CP*AP*G)-3', 5'-R(P*UP*GP*UP*C)-3', MAGNESIUM ION, ...
Authors:Ma, J.B, Yuan, Y.R, Meister, G, Pei, Y, Tuschl, T, Patel, D.J.
Deposit date:2005-02-11
Release date:2005-04-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein.
Nature, 434, 2005
1ZBH
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BU of 1zbh by Molmil
3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease
Descriptor: 3'-5' exonuclease ERI1, 5'-R(*CP*CP*GP*GP*CP*UP*CP*UP*UP*UP*UP*CP*AP*GP*AP*GP*CP*CP*GP*G)-3', ADENOSINE MONOPHOSPHATE, ...
Authors:Cheng, Y, Patel, D.J.
Deposit date:2005-04-08
Release date:2006-09-26
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for 3'-end specific recognition of histone mRNA stem-loop by 3'-exonuclease, a human nuclease that also targets siRNA
To be Published
6MUA
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BU of 6mua by Molmil
Crystal structure of Csm1-Csm4 subcomplex in the type III-A CRISPR-Csm interference complex
Descriptor: Uncharacterized protein Csm1, Uncharacterized protein Csm4
Authors:Jia, N, Patel, D.J.
Deposit date:2018-10-22
Release date:2019-01-09
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.91 Å)
Cite:Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Mol. Cell, 73, 2019
6UF1
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BU of 6uf1 by Molmil
Pistol ribozyme transition-state analog vanadate
Descriptor: MANGANESE (II) ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER)
Authors:Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
Deposit date:2019-09-23
Release date:2019-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
2ASD
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BU of 2asd by Molmil
oxoG-modified Insertion Ternary Complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, 5'-D(*CP*T*AP*AP*CP*(8OG)P*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', ...
Authors:Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J.
Deposit date:2005-08-23
Release date:2006-01-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
6NXF
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BU of 6nxf by Molmil
Crystal structure of mouse REC114 PH domain in complex with ANKRD31 C terminus
Descriptor: Ankyrin repeat domain 31, Meiotic recombination protein REC114
Authors:Wang, J, Patel, D.J.
Deposit date:2019-02-08
Release date:2019-04-24
Last modified:2019-12-04
Method:X-RAY DIFFRACTION (2.791 Å)
Cite:REC114 Partner ANKRD31 Controls Number, Timing, and Location of Meiotic DNA Breaks.
Mol.Cell, 74, 2019
2AU0
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BU of 2au0 by Molmil
Unmodified preinsertion binary complex
Descriptor: 5'-D(*CP*TP*AP*AP*CP*G*CP*TP*AP*CP*CP*AP*TP*CP*CP*AP*AP*CP*C)-3', 5'-D(*GP*GP*TP*TP*GP*GP*AP*TP*GP*GP*TP*AP*(DDG))-3', CALCIUM ION, ...
Authors:Rechkoblit, O, Malinina, L, Cheng, Y, Kuryavyi, V, Broyde, S, Geacintov, N.E, Patel, D.J.
Deposit date:2005-08-26
Release date:2006-01-10
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Stepwise Translocation of Dpo4 Polymerase during Error-Free Bypass of an oxoG Lesion
Plos Biol., 4, 2006
1YKQ
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BU of 1ykq by Molmil
Crystal structure of Diels-Alder ribozyme
Descriptor: CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION
Authors:Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YKV
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BU of 1ykv by Molmil
Crystal structure of the Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene
Descriptor: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, Diels-Alder ribozyme, MAGNESIUM ION
Authors:Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
Deposit date:2005-01-18
Release date:2005-02-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
1YLS
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BU of 1yls by Molmil
Crystal structure of selenium-modified Diels-Alder ribozyme complexed with the product of the reaction between N-pentylmaleimide and covalently attached 9-hydroxymethylanthracene
Descriptor: (3AS,9AS)-2-PENTYL-4-HYDROXYMETHYL-3A,4,9,9A-TETRAHYDRO-4,9[1',2']-BENZENO-1H-BENZ[F]ISOINDOLE-1,3(2H)-DIONE, MAGNESIUM ION, RNA Diels-Alder ribozyme
Authors:Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J.
Deposit date:2005-01-19
Release date:2005-02-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
6O6T
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BU of 6o6t by Molmil
Crystal structure of Csm6 H132A mutant
Descriptor: Csm6
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O75
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BU of 6o75 by Molmil
Crystal structure of Csm1-Csm4 cassette in complex with pppApA
Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, MANGANESE (II) ION, ...
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6UFJ
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BU of 6ufj by Molmil
Pistol ribozyme product crystal structure
Descriptor: MAGNESIUM ION, RNA (5'-R(*UP*CP*CP*AP*G)-3'), RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(23G))-3'), ...
Authors:Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
Deposit date:2019-09-24
Release date:2019-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
6O71
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BU of 6o71 by Molmil
Crystal structure of Csm6 in complex with cdA4 by soaking cdA4 into Csm6
Descriptor: Csm6, Cyclic DNA cdA4
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O7B
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BU of 6o7b by Molmil
Crystal structure of Csm1-Csm4 cassette in complex with cA4
Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, Cyclic RNA cA4
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
6OPF
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BU of 6opf by Molmil
Crystal structure of dmNxf2 UBA domain fused with Panoramix helix
Descriptor: Nuclear RNA export factor 2, Panoramix fusion
Authors:Wang, J, Patel, D.J.
Deposit date:2019-04-24
Release date:2019-07-03
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2 Å)
Cite:The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Nat.Struct.Mol.Biol., 26, 2019
6UEY
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BU of 6uey by Molmil
Pistol ribozyme transition-state analog vanadate
Descriptor: MAGNESIUM ION, RNA (5'-R(*UP*CP*UP*GP*CP*UP*CP*UP*CP*(GVA)*UP*CP*CP*AP*A)-3'), RNA (50-MER)
Authors:Teplova, M, Falschlunger, C, Krasheninina, O, Patel, D.J, Micura, R.
Deposit date:2019-09-23
Release date:2019-12-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crucial Roles of Two Hydrated Mg2+Ions in Reaction Catalysis of the Pistol Ribozyme.
Angew.Chem.Int.Ed.Engl., 59, 2020
6O47
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BU of 6o47 by Molmil
human cGAS core domain (K427E/K428E) bound with RU-521
Descriptor: (3~{S})-3-[1-[4,5-bis(chloranyl)-1~{H}-benzimidazol-2-yl]-3-methyl-5-oxidanyl-pyrazol-4-yl]-3~{H}-2-benzofuran-1-one, 2-(4,5-dichloro-1H-benzimidazol-2-yl)-5-methyl-4-[(1R)-3-oxo-1,3-dihydro-2-benzofuran-1-yl]-1,2-dihydro-3H-pyrazol-3-one, CITRIC ACID, ...
Authors:Xie, W, Lama, L, Adura, C, Glickman, J.F, Tuschl, T, Patel, D.J.
Deposit date:2019-02-28
Release date:2019-05-29
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.196 Å)
Cite:Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation.
Proc.Natl.Acad.Sci.USA, 116, 2019
6O7I
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BU of 6o7i by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary bigger complex in complex with cA4 in type III-A CRISPR-Cas system
Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019
207D
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BU of 207d by Molmil
SOLUTION STRUCTURE OF MITHRAMYCIN DIMERS BOUND TO PARTIALLY OVERLAPPING SITES ON DNA
Descriptor: 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE, 2,6-dideoxy-3-C-methyl-beta-D-ribo-hexopyranose-(1-3)-2,6-dideoxy-beta-D-galactopyranose-(1-3)-beta-D-Olivopyranose, DNA (5'-D(*TP*AP*GP*CP*TP*AP*GP*CP*TP*A)-3'), ...
Authors:Sastry, M, Fiala, R, Patel, D.J.
Deposit date:1995-04-20
Release date:1995-09-15
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Solution structure of mithramycin dimers bound to partially overlapping sites on DNA.
J.Mol.Biol., 251, 1995
6O6X
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BU of 6o6x by Molmil
Crystal structure of Csm6 W14A/E337A mutant in complex with cA4 by cocrystallization
Descriptor: Csm6, Cyclic RNA cA4
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O6S
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BU of 6o6s by Molmil
Crystal structure of Apo Csm6
Descriptor: Csm6
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.
Mol.Cell, 75, 2019
6O7H
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BU of 6o7h by Molmil
Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system
Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm2, Csm3, ...
Authors:Jia, N, Patel, D.J.
Deposit date:2019-03-07
Release date:2019-07-31
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.
Mol.Cell, 75, 2019

221716

数据于2024-06-26公开中

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