6OV0

Crystal structure of Csm6 in complex with A4>p by soaking A4>p into Csm6

Summary for 6OV0

• Entry DOI: 10.2210/pdb6ov0/pdb
• Descriptor: Uncharacterized protein, RNA (5'-R(*AP*AP*AP*(A23))-3') (2 entities in total)
• Functional Keywords: type iii-a crispr-cas system; csm6 in complex with ca4 by cocrystallization of csm6 and ca4, immune system, immune system-rna complex, immune system/rna
• Biological source: Thermococcus onnurineus (strain NA1); More
• Total number of polymer chains: 8
• Total formula weight: 204515.78

Authors

Jia, N.,Patel, D.J. (deposition date: 2019-05-06, release date: 2019-07-31, Last modification date: 2023-10-11)

• Primary citation: Jia, N.,Jones, R.,Yang, G.,Ouerfelli, O.,Patel, D.J.; CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity.; Mol.Cell, 75:944-956.e6, 2019; PubMed: 31326273; DOI: 10.1016/j.molcel.2019.06.014

Experimental method

X-RAY DIFFRACTION (2.8 Å)