6O6V
Crystal structure of Csm6 in complex with cA4 by soaking cA4 into Csm6
Summary for 6O6V
| Entry DOI | 10.2210/pdb6o6v/pdb |
| Related | 6O6S |
| Descriptor | Csm6, Cyclic RNA cA4 (3 entities in total) |
| Functional Keywords | type iii-a crispr-cas system; csm6 in complex with ca4, immune system, immune system-dna complex, immune system-rna complex, immune system/rna |
| Biological source | Thermococcus onnurineus More |
| Total number of polymer chains | 4 |
| Total formula weight | 102133.96 |
| Authors | Jia, N.,Patel, D.J. (deposition date: 2019-03-07, release date: 2019-07-31, Last modification date: 2023-10-11) |
| Primary citation | Jia, N.,Jones, R.,Yang, G.,Ouerfelli, O.,Patel, D.J. CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75:944-956.e6, 2019 Cited by PubMed: 31326273DOI: 10.1016/j.molcel.2019.06.014 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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