6O75

Crystal structure of Csm1-Csm4 cassette in complex with pppApA

Summary for 6O75

• Entry DOI: 10.2210/pdb6o75/pdb
• Descriptor: CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, RNA (5'-D(*(ATP))-R(P*A)-3'), ... (4 entities in total)
• Functional Keywords: type iii-a crispr-cas system, csm1-csm4 cassette in complex with pppapa, immune system, immune system-dna complex, immune system-rna complex, immune system/rna
• Biological source: Thermococcus onnurineus; More
• Total number of polymer chains: 4
• Total formula weight: 123708.36

Authors

Jia, N.,Patel, D.J. (deposition date: 2019-03-07, release date: 2019-07-31, Last modification date: 2023-10-11)

• Primary citation: Jia, N.,Jones, R.,Sukenick, G.,Patel, D.J.; Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path.; Mol.Cell, 75:933-943.e6, 2019; PubMed: 31326272; DOI: 10.1016/j.molcel.2019.06.013

Experimental method

X-RAY DIFFRACTION (2.6 Å)