6O7H

Cryo-EM structure of Csm-crRNA-target RNA ternary complex in complex with cA4 in type III-A CRISPR-Cas system

Summary for 6O7H

Entry DOI	10.2210/pdb6o7h/pdb
EMDB information	0641
Descriptor	CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), GUANOSINE-5'-MONOPHOSPHATE, Csm2, ... (10 entities in total)
Functional Keywords	cryo-em structure, csm-crrna-target rna ternary complex in complex with ca4, type iii crispr-cas systerm, immune system, immune system-rna-dna complex, immune system-rna complex, immune system/rna/dna
Biological source	Thermococcus onnurineus (strain NA1) More
Total number of polymer chains	9
Total formula weight	276608.86
Authors	Jia, N.,Patel, D.J. (deposition date: 2019-03-07, release date: 2019-07-31, Last modification date: 2024-03-20)
Primary citation	Jia, N.,Jones, R.,Sukenick, G.,Patel, D.J. Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75:933-943.e6, 2019 Cited by PubMed: 31326272 DOI: 10.1016/j.molcel.2019.06.013 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation