2HLC
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![BU of 2hlc by Molmil](/molmil-images/mine/2hlc) | HL COLLAGENASE STRUCTURE AT 1.7A RESOLUTION | Descriptor: | COLLAGENASE | Authors: | Broutin, I, Merigeau, K, Arnoux, B, Ducruix, A. | Deposit date: | 1997-01-08 | Release date: | 1997-09-04 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | 1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family. Acta Crystallogr.,Sect.D, 52, 1996
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3EW3
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![BU of 3ew3 by Molmil](/molmil-images/mine/3ew3) | the 1:2 complex between a Nterminal elongated prolactin and the extra cellular domain of the rat prolactin receptor | Descriptor: | Prolactin, Prolactin receptor | Authors: | Broutin, I, Jomain, J.B, England, P, Goffin, V. | Deposit date: | 2008-10-14 | Release date: | 2009-11-03 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Crystal structure of an affinity-matured prolactin complexed to its dimerized receptor reveals the topology of hormone binding site 2. J.Biol.Chem., 285, 2010
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1HYL
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![BU of 1hyl by Molmil](/molmil-images/mine/1hyl) | THE 1.8 A STRUCTURE OF COLLAGENASE FROM HYPODERMA LINEATUM | Descriptor: | HYPODERMA LINEATUM COLLAGENASE | Authors: | Broutin, I, Arnoux, B, Riche, C, Lecroisey, A, Keil, B, Pascard, C, Ducruix, A. | Deposit date: | 1995-05-02 | Release date: | 1995-07-31 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | 1.8 A structure of Hypoderma lineatum collagenase: a member of the serine proteinase family. Acta Crystallogr.,Sect.D, 52, 1996
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8Q8O
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![BU of 8q8o by Molmil](/molmil-images/mine/8q8o) | |
5IUY
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![BU of 5iuy by Molmil](/molmil-images/mine/5iuy) | Structural insights of the outer-membrane channel OprN | Descriptor: | CHLORIDE ION, FORMIC ACID, Multidrug efflux outer membrane protein OprN, ... | Authors: | Ntsogo, Y, Garnier, C, Phan, G, Monlezun, L, Benas, P, Broutin, I. | Deposit date: | 2016-03-18 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Xenon for tunnelling analysis of the efflux pump component OprN. PLoS ONE, 12, 2017
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4Y1K
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![BU of 4y1k by Molmil](/molmil-images/mine/4y1k) | |
1HF4
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![BU of 1hf4 by Molmil](/molmil-images/mine/1hf4) | STRUCTURAL EFFECTS OF MONOVALENT ANIONS ON POLYMORPHIC LYSOZYME CRYSTALS | Descriptor: | LYSOZYME, NITRATE ION, SODIUM ION | Authors: | Vaney, M.C, Broutin, I, Ries-Kautt, M, Ducruix, A. | Deposit date: | 2000-11-29 | Release date: | 2001-01-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Structural Effects of Monovalent Anions on Polymorphic Lysozyme Crystals Acta Crystallogr.,Sect.D, 57, 2001
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5ABD
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![BU of 5abd by Molmil](/molmil-images/mine/5abd) | CRYSTAL STRUCTURE OF VEGFR-1 DOMAIN 2 IN PRESENCE OF CU | Descriptor: | COPPER (II) ION, SODIUM ION, SULFATE ION, ... | Authors: | Gaucher, J.-F, Lascombe, M.-B, Reille-Seroussi, M, Gagey-Eilstein, N, Broussy, S, Coric, P, Seijo, B, Gautier, B, Liu, W.-Q, Huguenot, F, Inguimbert, N, Bouaziz, S, Vidal, M, Broutin, I. | Deposit date: | 2015-08-05 | Release date: | 2016-09-28 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.995 Å) | Cite: | Biophysical Studies of the Induced Dimerization of Human Vegf R Receptor 1 Binding Domain by Divalent Metals Competing with Vegf-A Plos One, 11, 2016
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3NPZ
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![BU of 3npz by Molmil](/molmil-images/mine/3npz) | Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL) | Descriptor: | Prolactin, Prolactin receptor | Authors: | Van Agthoven, J, England, P, Goffin, V, Broutin, I. | Deposit date: | 2010-06-29 | Release date: | 2010-10-06 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone. J.Mol.Biol., 404, 2010
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5NSW
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![BU of 5nsw by Molmil](/molmil-images/mine/5nsw) | Xenon for tunnelling analysis of the efflux pump component OprN. | Descriptor: | Multidrug efflux outer membrane protein OprN, NICKEL (II) ION, PALMITIC ACID, ... | Authors: | Phan, G, Prange, T, Enguene Ntsogo, Y.V, Garnier, C, Ducruix, A, Broutin, I. | Deposit date: | 2017-04-27 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Xenon for tunnelling analysis of the efflux pump component OprN. PLoS ONE, 12, 2017
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4CKV
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![BU of 4ckv by Molmil](/molmil-images/mine/4ckv) | Crystal structure of VEGFR-1 domain 2 in presence of Zn | Descriptor: | 1,2-ETHANEDIOL, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1, ZINC ION | Authors: | Gaucher, J.-F, Reille-Seroussi, M, Gagey-Eilstein, N, Broussy, S, Coric, P, Seijo, B, Lascombe, M.-B, Gautier, B, Liu, W.-Q, Huguenot, F, Inguimbert, N, Bouaziz, S, Vidal, M, Broutin, I. | Deposit date: | 2014-01-09 | Release date: | 2015-01-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.055 Å) | Cite: | Biophysical Studies of the Induced Dimerization of Human Vegf R Receptor 1 Binding Domain by Divalent Metals Competing with Vegf-A Plos One, 11, 2016
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4CL7
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![BU of 4cl7 by Molmil](/molmil-images/mine/4cl7) | Crystal structure of VEGFR-1 domain 2 in presence of Cobalt | Descriptor: | 1,2-ETHANEDIOL, COBALT (II) ION, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1 | Authors: | Gaucher, J.-F, Reille-Seroussi, M, Gagey-Eilstein, N, Broussy, S, Coric, P, Seijo, B, Lascombe, M.-B, Gautier, B, Liu, W.-Q, Huguenot, F, Inguimbert, N, Bouaziz, S, Vidal, M, Broutin, I. | Deposit date: | 2014-01-13 | Release date: | 2015-01-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Biophysical Studies of the Induced Dimerization of Human Vegf R Receptor 1 Binding Domain by Divalent Metals Competing with Vegf-A Plos One, 11, 2016
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2PRB
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![BU of 2prb by Molmil](/molmil-images/mine/2prb) | crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A | Descriptor: | Aminoglycoside 6-N-acetyltransferase type Ib11, COENZYME A | Authors: | Maurice, F, Broutin, I, Podglajen, I, Benas, P, Collatz, E, Dardel, F. | Deposit date: | 2007-05-04 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance. Embo Rep., 9, 2008
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2PR8
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![BU of 2pr8 by Molmil](/molmil-images/mine/2pr8) | crystal structure of aminoglycoside N-acetyltransferase AAC(6')-Ib11 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Aminoglycoside 6-N-acetyltransferase type Ib11 | Authors: | Maurice, F, Broutin, I, Podglajen, I, Benas, P, Collatz, E, Dardel, F. | Deposit date: | 2007-05-04 | Release date: | 2008-04-08 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance. Embo Rep., 9, 2008
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2QIR
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![BU of 2qir by Molmil](/molmil-images/mine/2qir) | Crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A and kanamycin | Descriptor: | (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, Aminoglycoside 6-N-acetyltransferase type Ib11, COENZYME A | Authors: | Maurice, F, Broutin, I, Podglajen, I, Benas, P, Collatz, E, Dardel, F. | Deposit date: | 2007-07-05 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance. Embo Rep., 9, 2008
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6ZRE
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![BU of 6zre by Molmil](/molmil-images/mine/6zre) | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | Descriptor: | Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ... | Authors: | Ntsogo Enguene, Y.V, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I. | Deposit date: | 2020-07-13 | Release date: | 2021-07-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa. To Be Published
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7AKZ
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![BU of 7akz by Molmil](/molmil-images/mine/7akz) | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa | Descriptor: | Outer membrane protein OprM, PALMITIC ACID, octyl beta-D-glucopyranoside | Authors: | Ntsogo Enguene, V.Y, Monlezun, L, Ma, M, Garnier, C, Lascombe, M.B, Salem, M, Guenard, S, Plesiat, P, Llanes, C, Phan, G, Broutin, I. | Deposit date: | 2020-10-02 | Release date: | 2022-04-13 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa To Be Published
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3D5K
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![BU of 3d5k by Molmil](/molmil-images/mine/3d5k) | |
6T7S
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![BU of 6t7s by Molmil](/molmil-images/mine/6t7s) | MexB structure solved by cryo-EM in nanodisc in absence of its protein partners | Descriptor: | Efflux pump membrane transporter | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | Deposit date: | 2019-10-23 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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6TA6
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![BU of 6ta6 by Molmil](/molmil-images/mine/6ta6) | MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs | Descriptor: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | Deposit date: | 2019-10-29 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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6TA5
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![BU of 6ta5 by Molmil](/molmil-images/mine/6ta5) | OprM-MexA complex from the MexAB-OprM Pseudomonas aeruginosa whole assembly reconstituted in nanodiscs | Descriptor: | Efflux pump membrane transporter, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Outer membrane protein OprM | Authors: | Glavier, M, Schoehn, G, Taveau, J.C, Phan, G, Daury, L, Lambert, O, Broutin, I. | Deposit date: | 2019-10-29 | Release date: | 2020-09-16 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11, 2020
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1JYQ
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![BU of 1jyq by Molmil](/molmil-images/mine/1jyq) | Xray Structure of Grb2 SH2 Domain Complexed with a Highly Affine Phospho Peptide | Descriptor: | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, mAZ-pY-(alpha Me)pY-N-NH2 peptide inhibitor | Authors: | Nioche, P, Liu, W.-Q, Broutin, I, Charbonnier, F, Latreille, M.-T, Vidal, M, Roques, B, Garbay, C, Ducruix, A. | Deposit date: | 2001-09-13 | Release date: | 2002-03-13 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J.Mol.Biol., 315, 2002
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1JYR
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![BU of 1jyr by Molmil](/molmil-images/mine/1jyr) | Xray Structure of Grb2 SH2 Domain Complexed with a Phosphorylated Peptide | Descriptor: | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, peptide: PSpYVNVQN | Authors: | Nioche, P, Liu, W.-Q, Broutin, I, Charbonnier, F, Latreille, M.-T, Vidal, M, Roques, B, Garbay, C, Ducruix, A. | Deposit date: | 2001-09-13 | Release date: | 2002-03-13 | Last modified: | 2018-10-10 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J.Mol.Biol., 315, 2002
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1JYU
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![BU of 1jyu by Molmil](/molmil-images/mine/1jyu) | Xray Structure of Grb2 SH2 Domain | Descriptor: | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 | Authors: | Nioche, P, Liu, W.-Q, Broutin, I, Charbonnier, F, Latreille, M.-T, Vidal, M, Roques, B, Garbay, C, Ducruix, A. | Deposit date: | 2001-09-13 | Release date: | 2002-03-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J.Mol.Biol., 315, 2002
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1B2K
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![BU of 1b2k by Molmil](/molmil-images/mine/1b2k) | Structural effects of monovalent anions on polymorphic lysozyme crystals | Descriptor: | IODIDE ION, PROTEIN (LYSOZYME) | Authors: | Vaney, M.C, Broutin, I, Ries-Kautt, M, Ducruix, A. | Deposit date: | 1998-11-26 | Release date: | 1998-12-02 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural effects of monovalent anions on polymorphic lysozyme crystals. Acta Crystallogr.,Sect.D, 57, 2001
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