3NPZ
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
Summary for 3NPZ
Entry DOI | 10.2210/pdb3npz/pdb |
Descriptor | Prolactin, Prolactin receptor (2 entities in total) |
Functional Keywords | protein protein complex, hormone-receptor complex, hormone, hormone-hormone receptor complex, hormone/hormone receptor |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P01236 Membrane; Single-pass type I membrane protein: P05710 |
Total number of polymer chains | 3 |
Total formula weight | 74733.04 |
Authors | Van Agthoven, J.,England, P.,Goffin, V.,Broutin, I. (deposition date: 2010-06-29, release date: 2010-10-06, Last modification date: 2023-09-06) |
Primary citation | van Agthoven, J.,Zhang, C.,Tallet, E.,Raynal, B.,Hoos, S.,Baron, B.,England, P.,Goffin, V.,Broutin, I. Structural characterization of the stem-stem dimerization interface between prolactin receptor chains complexed with the natural hormone. J.Mol.Biol., 404:112-126, 2010 Cited by PubMed: 20875426DOI: 10.1016/j.jmb.2010.09.036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.35 Å) |
Structure validation
Download full validation report