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6TA6

MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs

Summary for 6TA6
Entry DOI10.2210/pdb6ta6/pdb
Related6TA5
EMDB information10395
DescriptorOuter membrane protein OprM, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Efflux pump membrane transporter (3 entities in total)
Functional Keywordstransporter, efflux, proton motive force, bacterial resistance, antimicrobial protein
Biological sourcePseudomonas aeruginosa
More
Total number of polymer chains12
Total formula weight733105.16
Authors
Glavier, M.,Schoehn, G.,Taveau, J.C.,Phan, G.,Daury, L.,Lambert, O.,Broutin, I. (deposition date: 2019-10-29, release date: 2020-09-16, Last modification date: 2020-10-14)
Primary citationGlavier, M.,Puvanendran, D.,Salvador, D.,Decossas, M.,Phan, G.,Garnier, C.,Frezza, E.,Cece, Q.,Schoehn, G.,Picard, M.,Taveau, J.C.,Daury, L.,Broutin, I.,Lambert, O.
Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex.
Nat Commun, 11:4948-4948, 2020
Cited by
PubMed: 33009415
DOI: 10.1038/s41467-020-18770-5
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.2 Å)
Structure validation

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