2QIR

Crystal structure of aminoglycoside acetyltransferase AAC(6')-Ib in complex whith coenzyme A and kanamycin

Summary for 2QIR

Entry DOI	10.2210/pdb2qir/pdb
Related	2pr8 2prb
Descriptor	Aminoglycoside 6-N-acetyltransferase type Ib11, COENZYME A, (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, ... (4 entities in total)
Functional Keywords	aminoglycoside resistance, acetyltransferase, transferase
Biological source	Salmonella typhimurium
Total number of polymer chains	1
Total formula weight	23172.49
Authors	Maurice, F.,Broutin, I.,Podglajen, I.,Benas, P.,Collatz, E.,Dardel, F. (deposition date: 2007-07-05, release date: 2008-04-08, Last modification date: 2023-08-30)
Primary citation	Maurice, F.,Broutin, I.,Podglajen, I.,Benas, P.,Collatz, E.,Dardel, F. Enzyme structural plasticity and the emergence of broad-spectrum antibiotic resistance. Embo Rep., 9:344-349, 2008 Cited by PubMed: 18292754 DOI: 10.1038/embor.2008.9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation