6ZRE

Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa

Summary for 6ZRE

• Entry DOI: 10.2210/pdb6zre/pdb
• Descriptor: Outer membrane protein OprM, PALMITIC ACID, SULFATE ION, ... (4 entities in total)
• Functional Keywords: efflux pump, antibiotic resistance, tolc-like, outer-membrane channel., translocase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 2
• Total formula weight: 106663.43

Authors

Ntsogo Enguene, Y.V.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I. (deposition date: 2020-07-13, release date: 2021-07-28, Last modification date: 2024-01-31)

• Primary citation: Ntsogo Enguene, Y.V.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I.; Deciphering the role of OprM constrictions in the opening mechanism of the MexAB-OprM efflux pump from Pseudomonas aeruginosa.; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.8 Å)