4CL7

Crystal structure of VEGFR-1 domain 2 in presence of Cobalt

Summary for 4CL7

Entry DOI	10.2210/pdb4cl7/pdb
Related	4CKV
Descriptor	VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 1, COBALT (II) ION, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	receptor, metal-binding
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	4
Total formula weight	43827.24
Authors	Gaucher, J.-F.,Reille-Seroussi, M.,Gagey-Eilstein, N.,Broussy, S.,Coric, P.,Seijo, B.,Lascombe, M.-B.,Gautier, B.,Liu, W.-Q.,Huguenot, F.,Inguimbert, N.,Bouaziz, S.,Vidal, M.,Broutin, I. (deposition date: 2014-01-13, release date: 2015-01-28, Last modification date: 2023-12-20)
Primary citation	Gaucher, J.-F.,Reille-Seroussi, M.,Gagey-Eilstein, N.,Broussy, S.,Coric, P.,Seijo, B.,Lascombe, M.-B.,Gautier, B.,Liu, W.-Q.,Huguenot, F.,Inguimbert, N.,Bouaziz, S.,Vidal, M.,Broutin, I. Biophysical Studies of the Induced Dimerization of Human Vegf R Receptor 1 Binding Domain by Divalent Metals Competing with Vegf-A Plos One, 11:67755-, 2016 Cited by PubMed: 27942001 DOI: 10.1371/JOURNAL.PONE.0167755 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation