7AKZ

Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa

Summary for 7AKZ

• Entry DOI: 10.2210/pdb7akz/pdb
• Descriptor: Outer membrane protein OprM, PALMITIC ACID, octyl beta-D-glucopyranoside (3 entities in total)
• Functional Keywords: efflux pump, antibiotic resistance, tolc-like, channel., translocase
• Biological source: Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
• Total number of polymer chains: 2
• Total formula weight: 104116.20

Authors

Ntsogo Enguene, V.Y.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I. (deposition date: 2020-10-02, release date: 2022-04-13, Last modification date: 2024-01-31)

• Primary citation: Ntsogo Enguene, V.Y.,Monlezun, L.,Ma, M.,Garnier, C.,Lascombe, M.B.,Salem, M.,Guenard, S.,Plesiat, P.,Llanes, C.,Phan, G.,Broutin, I.; Deciphering the role of the channel constrictions in the opening mechanism of MexAB-OprM efflux pump from Pseudomonas aeruginosa; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.2 Å)