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3I85
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BU of 3i85 by Molmil
The Crystal Structure of Human EMMPRIN N-terminal Domain 1
Descriptor: Cervical EMMPRIN
Authors:Luo, J, Gilliland, G.L.
Deposit date:2009-07-09
Release date:2009-10-06
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of the EMMPRIN N-terminal domain 1: Dimerization via beta-strand swapping.
Proteins, 77, 2009
3IA6
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BU of 3ia6 by Molmil
X-ray Crystal structure of the nuclear hormone receptor PPAR-gamma in a complex with a PPAR gamma/alpha dual agonist
Descriptor: (2S)-3-{4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)propyl]phenyl}-2-(2H-1,2,3-triazol-2-yl)propanoic acid, Peroxisome proliferator-activated receptor gamma
Authors:Ohren, J.F.
Deposit date:2009-07-13
Release date:2009-10-13
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Synthesis and evaluation of novel alpha-heteroaryl-phenylpropanoic acid derivatives as PPARalpha/gamma dual agonists.
Bioorg.Med.Chem., 17, 2009
6XTZ
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BU of 6xtz by Molmil
Structure of Dally-like protein in complex with O-palmitoleoyl serine
Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Dally-like, ...
Authors:Vecchia, L, Jones, E.Y.
Deposit date:2020-01-16
Release date:2020-07-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Glypicans shield the Wnt lipid moiety to enable signalling at a distance.
Nature, 585, 2020
6YM0
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BU of 6ym0 by Molmil
Crystal structure of the SARS-CoV-2 receptor binding domain in complex with CR3022 Fab (crystal form 1)
Descriptor: Spike glycoprotein, heavy chain, light chain
Authors:Huo, J, Zhao, Y, Ren, J, Zhou, D, Ginn, H.M, Fry, E.E, Owens, R, Stuart, D.I.
Deposit date:2020-04-07
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (4.36 Å)
Cite:Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike.
Cell Host Microbe, 28, 2020
7JKB
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BU of 7jkb by Molmil
2xVH Fab
Descriptor: Anti-Her2, Anti-lysozyme
Authors:Lord, D.M, Zhou, Y.F.
Deposit date:2020-07-28
Release date:2020-11-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Bringing the Heavy Chain to Light: Creating a Symmetric, Bivalent IgG-Like Bispecific.
Antibodies, 9, 2020
3L7E
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BU of 3l7e by Molmil
Crystal structure of ANTI-IL-13 antibody C836
Descriptor: ACETATE ION, C836 HEAVY CHAIN, C836 LIGHT CHAIN, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2009-12-28
Release date:2010-11-10
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Antigen recognition by antibody C836 through adjustment of VL/VH packing
Acta Crystallogr.,Sect.F, 67, 2011
4KQ4
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BU of 4kq4 by Molmil
Crystal structure of Anti-IL-17A antibody CNTO7357
Descriptor: CNTO7357 heavy chain, CNTO7357 light chain, NICKEL (II) ION
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-05-14
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
8BOE
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BU of 8boe by Molmil
Human Carbonic Anhydrase I in complex with (S)-4-(3-(1-(6-nitropyridin-2-yl)pyrrolidin-3-yl)thioureido)benzenesulfonamide
Descriptor: 1-[(3~{R})-1-(6-nitropyridin-2-yl)pyrrolidin-3-yl]-3-(4-sulfamoylphenyl)thiourea, Carbonic anhydrase 2, GLYCEROL, ...
Authors:Angeli, A, Ferraroni, M.
Deposit date:2022-11-15
Release date:2023-11-29
Last modified:2024-06-12
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:First-in-Class Dual Hybrid Carbonic Anhydrase Inhibitors and Transient Receptor Potential Vanilloid 1 Agonists Revert Oxaliplatin-Induced Neuropathy.
J.Med.Chem., 66, 2023
4KQ3
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BU of 4kq3 by Molmil
Crystal structure of Anti-IL-17A antibody CNTO3186
Descriptor: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO3186 heavy chain, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-05-14
Release date:2014-03-26
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural evidence for a constrained conformation of short CDR-L3 in antibodies.
Proteins, 82, 2014
4KMT
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BU of 4kmt by Molmil
Crystal structure of human germline antibody 5-51/O12
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-05-08
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4MAU
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BU of 4mau by Molmil
Crystal structure of anti-ST2L antibody C2244
Descriptor: C2244 heavy chain, C2244 light chain, FORMIC ACID, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-16
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4M6O
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BU of 4m6o by Molmil
Crystal structure of anti-NGF antibody CNTO7309
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CNTO7309 heavy chain, CNTO7309 light chain, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-09
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4M7K
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BU of 4m7k by Molmil
Crystal structure of anti-tissue factor antibody 10H10
Descriptor: 10H10 heavy chain, 10H10 light chain, ACETATE ION, ...
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2013-08-12
Release date:2014-03-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Antibody modeling assessment II. Structures and models.
Proteins, 82, 2014
4PS4
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BU of 4ps4 by Molmil
Crystal structure of the complex between IL-13 and M1295 FAB
Descriptor: Interleukin-13, M1295 HEAVY CHAIN, M1295 LIGHT CHAIN
Authors:Teplyakov, A, Obmolova, G, Malia, T, Gilliland, G.L.
Deposit date:2014-03-06
Release date:2014-03-19
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398, 2010
6VCA
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BU of 6vca by Molmil
TB38 complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 5'-nucleotidase, ...
Authors:Zhou, Y.F, Lord, D.M.
Deposit date:2019-12-20
Release date:2020-11-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.73 Å)
Cite:A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
J.Biol.Chem., 295, 2020
6VC9
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BU of 6vc9 by Molmil
TB19 complex
Descriptor: 1,2-ETHANEDIOL, 5'-nucleotidase, ecto (CD73), ...
Authors:Zhou, Y.F, Lord, D.M.
Deposit date:2019-12-20
Release date:2020-11-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.
J.Biol.Chem., 295, 2020
7T86
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BU of 7t86 by Molmil
Crystal Structure of Fab CR5133 / Phospho-SD Peptide Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody Fab CR5133 Heavy Chain, Antibody Fab CR5133 Light Chain, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
7T82
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BU of 7t82 by Molmil
Crystal Structure of LEUKOCIDIN E/CENTYRIN S26/FAB B438
Descriptor: Antibody Fab Heavy Chain, Antibody Fab Light Chain, Centyrin S26, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
7T87
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BU of 7t87 by Molmil
CRYSTAL STRUCTURE OF LEUKOCIDIN AB/CENTYRIN S17/FAB 214F COMPLEX
Descriptor: Antibody Fab B214 Heavy Chain, Antibody Fab B214 Light Chain, Centyrin S17, ...
Authors:Luo, J, Malia, T.J, Buckley, P.T.
Deposit date:2021-12-15
Release date:2023-01-11
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections.
Cell Host Microbe, 31, 2023
4DN4
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BU of 4dn4 by Molmil
Crystal structure of the complex between cnto888 fab and mcp-1 mutant p8a
Descriptor: ACETATE ION, C-C motif chemokine 2, CNTO888 HEAVY CHAIN, ...
Authors:Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012
1FGV
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BU of 1fgv by Molmil
X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65
Descriptor: H52 FV (HEAVY CHAIN), H52 FV (LIGHT CHAIN)
Authors:Eigenbrot, C, Kessler, J.
Deposit date:1993-11-01
Release date:1994-01-31
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65.
Proteins, 18, 1994
7JGU
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BU of 7jgu by Molmil
Structure of FN3tt mut
Descriptor: Fibronectin type-III domain-containing protein, PENTAETHYLENE GLYCOL
Authors:Luo, J, Boucher, L.E.
Deposit date:2020-07-19
Release date:2021-07-21
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Surface salt bridges contribute to the extreme thermal stability of an FN3-like domain from a thermophilic bacterium.
Proteins, 90, 2022
2FGW
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BU of 2fgw by Molmil
X-RAY STRUCTURES OF FRAGMENTS FROM BINDING AND NONBINDING VERSIONS OF A HUMANIZED ANTI-CD18 ANTIBODY: STRUCTURAL INDICATIONS OF THE KEY ROLE OF VH RESIDUES 59 TO 65
Descriptor: H52 FAB (HEAVY CHAIN), H52 FAB (LIGHT CHAIN)
Authors:Eigenbrot, C, Kessler, J.
Deposit date:1994-01-16
Release date:1994-04-30
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65.
Proteins, 18, 1994
5KF4
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BU of 5kf4 by Molmil
Crystal structure of FN3 domain (Residues P368-P466) of Human collagen XX
Descriptor: Collagen alpha-1(XX) chain
Authors:Xie, Y, Cheng, Z, Zhao, J.
Deposit date:2016-06-12
Release date:2016-07-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the second fibronectin type III (FN3) domain from human collagen alpha 1 type XX
Acta Crystallogr F Struct Biol Commun, 73, 2017
4DN3
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BU of 4dn3 by Molmil
Crystal structure of anti-mcp-1 antibody cnto888
Descriptor: CNTO888 HEAVY CHAIN, CNTO888 LIGHT CHAIN
Authors:Obmolova, G, Teplyakov, A, Malia, T, Grygiel, T, Sweet, R, Snyder, L, Gilliland, G.
Deposit date:2012-02-08
Release date:2012-10-03
Last modified:2018-01-24
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for high selectivity of anti-CCL2 neutralizing antibody CNTO 888.
Mol.Immunol., 51, 2012

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