6VC9

TB19 complex

Summary for 6VC9

• Entry DOI: 10.2210/pdb6vc9/pdb
• Related: 6vca
• Descriptor: TB19 heavy chain, TB19 light chain, 5'-nucleotidase, ecto (CD73), isoform CRA_a, ... (9 entities in total)
• Functional Keywords: fab, enzyme, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 109092.89

Authors

Zhou, Y.F.,Lord, D.M. (deposition date: 2019-12-20, release date: 2020-11-11, Last modification date: 2023-10-11)

• Primary citation: Stefano, J.E.,Lord, D.M.,Zhou, Y.,Jaworski, J.,Hopke, J.,Travaline, T.,Zhang, N.,Wong, K.,Lennon, A.,He, T.,Bric-Furlong, E.,Cherrie, C.,Magnay, T.,Remy, E.,Brondyk, W.,Qiu, H.,Radosevic, K.; A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.; J.Biol.Chem., 295:18379-18389, 2020; PubMed: 33122192; DOI: 10.1074/jbc.RA120.012395

Experimental method

X-RAY DIFFRACTION (2.25 Å)