6VCA
TB38 complex
Summary for 6VCA
Entry DOI | 10.2210/pdb6vca/pdb |
Related | 6vc9 |
Descriptor | 5'-nucleotidase, ecto (CD73), isoform CRA_a, TB38 heavy chain, TB38 light chain, ... (6 entities in total) |
Functional Keywords | fab, enzyme, immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 12 |
Total formula weight | 428805.50 |
Authors | Zhou, Y.F.,Lord, D.M. (deposition date: 2019-12-20, release date: 2020-11-11, Last modification date: 2023-10-11) |
Primary citation | Stefano, J.E.,Lord, D.M.,Zhou, Y.,Jaworski, J.,Hopke, J.,Travaline, T.,Zhang, N.,Wong, K.,Lennon, A.,He, T.,Bric-Furlong, E.,Cherrie, C.,Magnay, T.,Remy, E.,Brondyk, W.,Qiu, H.,Radosevic, K. A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms. J.Biol.Chem., 295:18379-18389, 2020 Cited by PubMed: 33122192DOI: 10.1074/jbc.RA120.012395 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.73 Å) |
Structure validation
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