6VCA

TB38 complex

Summary for 6VCA

• Entry DOI: 10.2210/pdb6vca/pdb
• Related: 6vc9
• Descriptor: 5'-nucleotidase, ecto (CD73), isoform CRA_a, TB38 heavy chain, TB38 light chain, ... (6 entities in total)
• Functional Keywords: fab, enzyme, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 428805.50

Authors

Zhou, Y.F.,Lord, D.M. (deposition date: 2019-12-20, release date: 2020-11-11, Last modification date: 2023-10-11)

• Primary citation: Stefano, J.E.,Lord, D.M.,Zhou, Y.,Jaworski, J.,Hopke, J.,Travaline, T.,Zhang, N.,Wong, K.,Lennon, A.,He, T.,Bric-Furlong, E.,Cherrie, C.,Magnay, T.,Remy, E.,Brondyk, W.,Qiu, H.,Radosevic, K.; A highly potent CD73 biparatopic antibody blocks organization of the enzyme active site through dual mechanisms.; J.Biol.Chem., 295:18379-18389, 2020; PubMed: 33122192; DOI: 10.1074/jbc.RA120.012395

Experimental method

X-RAY DIFFRACTION (3.73 Å)