Crystal structure of the complex between IL-13 and M1295 FAB

Replaces:  3L5Y

Summary for 4PS4

Related3L5W 3L5X
DescriptorM1295 LIGHT CHAIN, M1295 HEAVY CHAIN, Interleukin-13 (3 entities in total)
Functional Keywordsimmunoglobulin fold, alpha-helical bundle, cytokine, disulfide bond, glycoprotein, secreted, monoclonal antibody, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total molecular weight60393.31
Teplyakov, A.,Obmolova, G.,Malia, T.,Gilliland, G.L. (deposition date: 2014-03-06, release date: 2014-03-19, Last modification date: 2019-12-25)
Primary citation
Fransson, J.,Teplyakov, A.,Raghunathan, G.,Chi, E.,Cordier, W.,Dinh, T.,Feng, Y.,Giles-Komar, J.,Gilliland, G.,Lollo, B.,Malia, T.J.,Nishioka, W.,Obmolova, G.,Zhao, S.,Zhao, Y.,Swanson, R.V.,Almagro, J.C.
Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398:214-, 2010
PubMed: 20226193 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2010.03.004
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2693 0.2% 2.9% 2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload