4PS4

Crystal structure of the complex between IL-13 and M1295 FAB

Replaces:  3L5Y

Summary for 4PS4

Related3L5W 3L5X
DescriptorM1295 LIGHT CHAIN, M1295 HEAVY CHAIN, Interleukin-13 (3 entities in total)
Functional Keywordsimmunoglobulin fold, alpha-helical bundle, cytokine, disulfide bond, glycoprotein, secreted, monoclonal antibody, immune system
Biological sourceHomo sapiens (human)
Total number of polymer chains3
Total molecular weight60393.31
Authors
Teplyakov, A.,Obmolova, G.,Malia, T.,Gilliland, G.L. (deposition date: 2014-03-06, release date: 2014-03-19, Last modification date: 2019-12-25)
Primary citation
Fransson, J.,Teplyakov, A.,Raghunathan, G.,Chi, E.,Cordier, W.,Dinh, T.,Feng, Y.,Giles-Komar, J.,Gilliland, G.,Lollo, B.,Malia, T.J.,Nishioka, W.,Obmolova, G.,Zhao, S.,Zhao, Y.,Swanson, R.V.,Almagro, J.C.
Human Framework Adaptation of a Mouse Anti-Human Il-13 Antibody.
J.Mol.Biol., 398:214-, 2010
PubMed: 20226193 (PDB entries with the same primary citation)
DOI: 10.1016/J.JMB.2010.03.004
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2693 0.2% 2.9% 2.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload