7T87

CRYSTAL STRUCTURE OF LEUKOCIDIN AB/CENTYRIN S17/FAB 214F COMPLEX

Summary for 7T87

Entry DOI	10.2210/pdb7t87/pdb
Descriptor	Leukocidin B, Leukocidin A, Antibody Fab B214 Light Chain, ... (5 entities in total)
Functional Keywords	staphylcoccus aureus, lukocidin ab, centyrin, fab, toxin
Biological source	Staphylococcaceae More
Total number of polymer chains	5
Total formula weight	133391.91
Authors	Luo, J.,Malia, T.J.,Buckley, P.T. (deposition date: 2021-12-15, release date: 2023-01-11, Last modification date: 2023-10-25)
Primary citation	Buckley, P.T.,Chan, R.,Fernandez, J.,Luo, J.,Lacey, K.A.,DuMont, A.L.,O'Malley, A.,Brezski, R.J.,Zheng, S.,Malia, T.,Whitaker, B.,Zwolak, A.,Payne, A.,Clark, D.,Sigg, M.,Lacy, E.R.,Kornilova, A.,Kwok, D.,McCarthy, S.,Wu, B.,Morrow, B.,Nemeth-Seay, J.,Petley, T.,Wu, S.,Strohl, W.R.,Lynch, A.S.,Torres, V.J. Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Cell Host Microbe, 31:751-765.e11, 2023 Cited by PubMed: 37098341 DOI: 10.1016/j.chom.2023.04.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3 Å)

Structure validation