4M6O

Crystal structure of anti-NGF antibody CNTO7309

Summary for 4M6O

• Entry DOI: 10.2210/pdb4m6o/pdb
• Descriptor: CNTO7309 light chain, CNTO7309 heavy chain, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... (6 entities in total)
• Functional Keywords: immunoglobulin fold, antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 48779.50

Authors

Teplyakov, A.,Obmolova, G.,Malia, T.,Gilliland, G.L. (deposition date: 2013-08-09, release date: 2014-03-26, Last modification date: 2023-09-20)

• Primary citation: Teplyakov, A.,Luo, J.,Obmolova, G.,Malia, T.J.,Sweet, R.,Stanfield, R.L.,Kodangattil, S.,Almagro, J.C.,Gilliland, G.L.; Antibody modeling assessment II. Structures and models.; Proteins, 82:1563-1582, 2014; PubMed: 24633955; DOI: 10.1002/prot.24554

Experimental method

X-RAY DIFFRACTION (2.8 Å)