7T86

Crystal Structure of Fab CR5133 / Phospho-SD Peptide Complex

Summary for 7T86

Entry DOI	10.2210/pdb7t86/pdb
Descriptor	Antibody Fab CR5133 Light Chain, Antibody Fab CR5133 Heavy Chain, Phospho-SD Peptide, ... (5 entities in total)
Functional Keywords	staphylcoccus aureus, sd repeat, phospho sd peptide, fab, cr5133, toxin
Biological source	Homo sapiens More
Total number of polymer chains	12
Total formula weight	196661.42
Authors	Luo, J.,Malia, T.J.,Buckley, P.T. (deposition date: 2021-12-15, release date: 2023-01-11, Last modification date: 2023-10-25)
Primary citation	Buckley, P.T.,Chan, R.,Fernandez, J.,Luo, J.,Lacey, K.A.,DuMont, A.L.,O'Malley, A.,Brezski, R.J.,Zheng, S.,Malia, T.,Whitaker, B.,Zwolak, A.,Payne, A.,Clark, D.,Sigg, M.,Lacy, E.R.,Kornilova, A.,Kwok, D.,McCarthy, S.,Wu, B.,Morrow, B.,Nemeth-Seay, J.,Petley, T.,Wu, S.,Strohl, W.R.,Lynch, A.S.,Torres, V.J. Multivalent human antibody-centyrin fusion protein to prevent and treat Staphylococcus aureus infections. Cell Host Microbe, 31:751-765.e11, 2023 Cited by PubMed: 37098341 DOI: 10.1016/j.chom.2023.04.004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation