8GRU
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![BU of 8gru by Molmil](/molmil-images/mine/8gru) | Crystal structure of a constitutively active mutant of the alpha beta heterodimer of human IDH3 in complex with ICT, NAD and Ca | Descriptor: | CALCIUM ION, Human IDH3 alpha subunit, ISOCITRIC ACID, ... | Authors: | Sun, P, Chen, X, Ding, J. | Deposit date: | 2022-09-02 | Release date: | 2022-11-30 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | Structures of a constitutively active mutant of human IDH3 reveal new insights into the mechanisms of allosteric activation and the catalytic reaction. J.Biol.Chem., 298, 2022
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8GRB
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6KBU
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![BU of 6kbu by Molmil](/molmil-images/mine/6kbu) | Crystal structure of yedK | Descriptor: | GLYCEROL, SOS response-associated protein | Authors: | Wang, N, Bao, H, Huang, H. | Deposit date: | 2019-06-26 | Release date: | 2019-07-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK. Nucleic Acids Res., 47, 2019
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8GL9
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![BU of 8gl9 by Molmil](/molmil-images/mine/8gl9) | Co-crystal structure of caPCNA bound to AOH1160 derivative 1LE | Descriptor: | CHLORIDE ION, N~2~-(naphthalene-1-carbonyl)-N-(2-phenoxyphenyl)-L-alpha-glutamine, Proliferating cell nuclear antigen | Authors: | Jossart, J, Kenjic, N, Malkas, L.H, Hickey, R.J, Perry, J.J. | Deposit date: | 2023-03-21 | Release date: | 2023-07-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Small molecule targeting of transcription-replication conflict for selective chemotherapy. Cell Chem Biol, 30, 2023
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8GLA
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![BU of 8gla by Molmil](/molmil-images/mine/8gla) | |
6KBZ
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6KBX
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6KBS
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![BU of 6kbs by Molmil](/molmil-images/mine/6kbs) | Crystal structure of yedK in complex with ssDNA | Descriptor: | DNA (5'-D(*CP*GP*GP*TP*CP*GP*AP*TP*TP*C)-3'), SOS response-associated protein | Authors: | Wang, N, Bao, H, Huang, H. | Deposit date: | 2019-06-26 | Release date: | 2019-07-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK. Nucleic Acids Res., 47, 2019
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6KCQ
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8GBN
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![BU of 8gbn by Molmil](/molmil-images/mine/8gbn) | Structure of Apo Human SIRT5 P114T Mutant | Descriptor: | 1,2-ETHANEDIOL, NAD-dependent protein deacylase sirtuin-5, mitochondrial, ... | Authors: | Petrunak, E.M, Stuckey, J.A. | Deposit date: | 2023-02-26 | Release date: | 2024-06-05 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice. Iscience, 27, 2024
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8GBL
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![BU of 8gbl by Molmil](/molmil-images/mine/8gbl) | Structure of Apo Human SIRT5 | Descriptor: | NAD-dependent protein deacylase sirtuin-5, mitochondrial, ZINC ION | Authors: | Petrunak, E.M, Stuckey, J.A. | Deposit date: | 2023-02-26 | Release date: | 2024-06-05 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.24 Å) | Cite: | Human SIRT5 variants with reduced stability and activity do not cause neuropathology in mice. Iscience, 27, 2024
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8H8X
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![BU of 8h8x by Molmil](/molmil-images/mine/8h8x) | Cryo-EM structure of HACE1 monomer | Descriptor: | E3 ubiquitin-protein ligase HACE1 | Authors: | Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J. | Deposit date: | 2022-10-24 | Release date: | 2023-06-28 | Last modified: | 2024-01-10 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization. Adv Sci, 10, 2023
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8HAE
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![BU of 8hae by Molmil](/molmil-images/mine/8hae) | Cryo-EM structure of HACE1 dimer | Descriptor: | E3 ubiquitin-protein ligase HACE1 | Authors: | Singh, S, Machida, S, Tulsian, N.K, Choong, Y.K, Ng, J, Shanker, S, Yaochen, L.D, Shi, J, Sivaraman, J, Machida, S. | Deposit date: | 2022-10-26 | Release date: | 2023-06-28 | Last modified: | 2023-10-04 | Method: | ELECTRON MICROSCOPY (4.55 Å) | Cite: | Structural Basis for the Enzymatic Activity of the HACE1 HECT-Type E3 Ligase Through N-Terminal Helix Dimerization. Adv Sci, 10, 2023
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6LBC
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![BU of 6lbc by Molmil](/molmil-images/mine/6lbc) | shrimp ferritin-T158R | Descriptor: | FE (III) ION, Ferritin | Authors: | Zhao, G, Chen, H, Zhang, T. | Deposit date: | 2019-11-14 | Release date: | 2020-11-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.801 Å) | Cite: | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
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6LBD
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![BU of 6lbd by Molmil](/molmil-images/mine/6lbd) | shrimp ferritin T158R G159R | Descriptor: | CHLORIDE ION, FE (III) ION, Ferritin | Authors: | Zhao, G, Chen, H. | Deposit date: | 2019-11-14 | Release date: | 2020-11-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.386 Å) | Cite: | Construction of thermally robust and porous shrimp ferritin crystalline for molecular encapsulation through intermolecular arginine-arginine attractions. Food Chem, 349, 2021
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7XXY
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![BU of 7xxy by Molmil](/molmil-images/mine/7xxy) | Macaca mulatta galectin-10/Charcot-Leyden crystal protein with lactose | Descriptor: | Galectin-10/Charcot-Leyden crystal protein, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J.Y. | Deposit date: | 2022-05-31 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma. Acta Biochim.Biophys.Sin., 55, 2023
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7XXW
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7XXV
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![BU of 7xxv by Molmil](/molmil-images/mine/7xxv) | Macaca fascicularis galectin-10/Charcot-Leyden crystal protein with lactose | Descriptor: | Galectin, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Su, J.Y. | Deposit date: | 2022-05-31 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma. Acta Biochim.Biophys.Sin., 55, 2023
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7XXU
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![BU of 7xxu by Molmil](/molmil-images/mine/7xxu) | Macaca fascicularis galectin-10/Charcot-Leyden crystal protein | Descriptor: | Galectin | Authors: | Su, J.Y. | Deposit date: | 2022-05-31 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma. Acta Biochim.Biophys.Sin., 55, 2023
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7XXZ
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![BU of 7xxz by Molmil](/molmil-images/mine/7xxz) | Macaca mulatta galectin-10/Charcot-Leyden crystal protein with glycerol | Descriptor: | GLYCEROL, Galectin-10/Charcot-Leyden crystal protein | Authors: | Su, J.Y. | Deposit date: | 2022-05-31 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma. Acta Biochim.Biophys.Sin., 55, 2023
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7XXX
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![BU of 7xxx by Molmil](/molmil-images/mine/7xxx) | Macaca mulatta galectin-10/Charcot-Leyden crystal protein | Descriptor: | Galectin-10/Charcot-Leyden crystal protein | Authors: | Su, J.Y. | Deposit date: | 2022-05-31 | Release date: | 2023-04-12 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma. Acta Biochim.Biophys.Sin., 55, 2023
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6KIJ
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![BU of 6kij by Molmil](/molmil-images/mine/6kij) | Crystal structure of yedK with ssDNA containing an abasic site | Descriptor: | DNA (5'-D(*GP*AP*TP*TP*CP*GP*TP*CP*G)-3'), GLYCEROL, PENTANE-3,4-DIOL-5-PHOSPHATE, ... | Authors: | Wang, N, Bao, H, Huang, H. | Deposit date: | 2019-07-18 | Release date: | 2019-08-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.58 Å) | Cite: | Molecular basis of abasic site sensing in single-stranded DNA by the SRAP domain of E. coli yedK. Nucleic Acids Res., 47, 2019
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7C7E
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![BU of 7c7e by Molmil](/molmil-images/mine/7c7e) | Crystal structure of C terminal domain of Escherichia coli DgoR | Descriptor: | Putative DNA-binding transcriptional regulator, SULFATE ION, TRIETHYLENE GLYCOL, ... | Authors: | Lin, W. | Deposit date: | 2020-05-25 | Release date: | 2021-01-20 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Structural and Functional Analyses of the Transcription Repressor DgoR From Escherichia coli Reveal a Divalent Metal-Containing D-Galactonate Binding Pocket. Front Microbiol, 11, 2020
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7WZ6
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![BU of 7wz6 by Molmil](/molmil-images/mine/7wz6) | Crystal structure of MyoD-E47 | Descriptor: | Isoform E47 of Transcription factor E2-alpha, Myoblast determination protein 1 | Authors: | Zhong, J, Huang, Y, Ma, J. | Deposit date: | 2022-02-17 | Release date: | 2022-06-22 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structural basis of the bHLH domains of MyoD-E47 heterodimer. Biochem.Biophys.Res.Commun., 621, 2022
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7CFP
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![BU of 7cfp by Molmil](/molmil-images/mine/7cfp) | |