4D8D
 
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3VMQ
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase: Apoenzyme | | Descriptor: | MAGNESIUM ION, Monofunctional glycosyltransferase | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.518 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VMT
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with a Lipid II analog | | Descriptor: | MAGNESIUM ION, Monofunctional glycosyltransferase, [(2R,3R,4R,5S,6R)-4-[(2R)-1-[[(2S)-1-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxidanylidene-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethylamino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]oxy-3-acetamido-5-[(2S,3R,4R,5R,6R)-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-(hydroxymethyl)oxan-2-yl] [oxidanyl(3,7,11,15,19,23,27,31,35,39,43-undecamethyltetratetraconta-2,6,10,14,18,22,26,30,34,38,42-undecaenoxy)phosphoryl] hydrogen phosphate | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.299 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3VMS
 | | Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex with NBD-Lipid II | | Descriptor: | Monofunctional glycosyltransferase | | Authors: | Huang, C.Y, Shih, H.W, Lin, L.Y, Tien, Y.W, Cheng, T.J.R, Cheng, W.C, Wong, C.H, Ma, C. | | Deposit date: | 2011-12-15 | | Release date: | 2012-04-18 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.202 Å) | | Cite: | Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism
Proc.Natl.Acad.Sci.USA, 109, 2012
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3BRW
 | | Structure of the Rap-RapGAP complex | | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | Authors: | Scrima, A, Thomas, C, Deaconescu, D, Wittinghofer, A. | | Deposit date: | 2007-12-21 | | Release date: | 2008-03-11 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | The Rap-RapGAP complex: GTP hydrolysis without catalytic glutamine and arginine residues
Embo J., 27, 2008
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5E4E
 | | Engineered Interleukin-13 bound to receptor | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-13, Interleukin-13 receptor subunit alpha-1, ... | | Authors: | Moraga, I, Thomas, C, Jude, K.M, Garcia, K.C. | | Deposit date: | 2015-10-05 | | Release date: | 2015-12-02 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci.Signal., 8, 2015
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1R3B
 | | Solution structure of xenopus laevis Mob1 | | Descriptor: | MOB1 | | Authors: | Ponchon, L, Dumas, C, Kajava, A.V, Fesquet, D, Padilla, A. | | Deposit date: | 2003-10-01 | | Release date: | 2004-09-28 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | NMR solution structure of Mob1, a mitotic exit network protein and its interaction with an NDR kinase peptide
J.Mol.Biol., 337, 2004
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3U2E
 | | EAL domain of phosphodiesterase PdeA in complex with 5'-pGpG and Mg++ | | Descriptor: | GGDEF family protein, MAGNESIUM ION, RNA (5'-R(P*GP*G)-3') | | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-10-03 | | Release date: | 2011-10-12 | | Last modified: | 2023-12-06 | | Method: | X-RAY DIFFRACTION (2.32 Å) | | Cite: | EAL domain from Caulobacter crescentus in complex with 5'-pGpG and Mg++
To be Published
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3H6O
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one, Pyruvate kinase isozymes M1/M2, ... | | Authors: | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-04-23 | | Release date: | 2009-05-05 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3S83
 | | EAL domain of phosphodiesterase PdeA | | Descriptor: | GGDEF family protein, POTASSIUM ION | | Authors: | Filippova, E.V, Minasov, G, Shuvalova, L, Kiryukhina, O, Massa, C, Schirmer, T, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2011-05-27 | | Release date: | 2011-06-29 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (1.34 Å) | | Cite: | Crystal structure of EAL domain from Caulobacter crescentus CB15
To be Published
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3ZJB
 | | The structure of the TRAF domain of human TRAF4 | | Descriptor: | CHLORIDE ION, TNF RECEPTOR-ASSOCIATED FACTOR 4 | | Authors: | McEwen, A.G, Poussin-Courmontagne, P, Rousseau, A, Rogna, D, Nomine, Y, Rio, M.-C, Tomasetto, C, Alpy, F. | | Deposit date: | 2013-01-17 | | Release date: | 2013-12-04 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Traf4 is a Novel Phosphoinositide-Binding Protein Modulating Tight Junctions and Favoring Cell Migration.
Plos Biol., 11, 2013
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3GQY
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-[(4-methoxyphenyl)sulfonyl]piperazine, L(+)-TARTARIC ACID, ... | | Authors: | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-03-24 | | Release date: | 2009-04-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3GR4
 | | Activator-Bound Structure of Human Pyruvate Kinase M2 | | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, 1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine, ADENOSINE-5'-DIPHOSPHATE, ... | | Authors: | Hong, B, Dimov, S, Tempel, W, Auld, D, Thomas, C, Boxer, M, Jianq, J.-K, Skoumbourdis, A, Min, S, Southall, N, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Inglese, J, Park, H, Structural Genomics Consortium (SGC) | | Deposit date: | 2009-03-24 | | Release date: | 2009-04-07 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Activator-Bound Structures of Human Pyruvate Kinase M2
to be published
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3F6N
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3FWL
 | | Crystal Structure of the Full-Length Transglycosylase PBP1b from Escherichia coli | | Descriptor: | MOENOMYCIN, Penicillin-binding protein 1B | | Authors: | Sung, M.T, Lai, Y.T, Huang, C.Y, Chou, L.Y, Wong, C.H, Ma, C. | | Deposit date: | 2009-01-19 | | Release date: | 2009-06-02 | | Last modified: | 2017-11-01 | | Method: | X-RAY DIFFRACTION (3.086 Å) | | Cite: | Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli.
Proc.Natl.Acad.Sci.USA, 106, 2009
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4GAI
 | | Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra | | Descriptor: | EBI-005 | | Authors: | Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. | | Deposit date: | 2012-07-25 | | Release date: | 2013-02-20 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Design of a superior cytokine antagonist for topical ophthalmic use.
Proc.Natl.Acad.Sci.USA, 110, 2013
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1NDL
 | | THE AWD NUCLEOTIDE DIPHOSPHATE KINASE FROM DROSOPHILA | | Descriptor: | NUCLEOSIDE DIPHOSPHATE KINASE | | Authors: | Janin, J, Chiadmi, M, Dumas, C, Lascu, I, Lebras, G, Morera, S, Veron, M. | | Deposit date: | 1993-11-27 | | Release date: | 1994-04-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila.
Structure, 1, 1993
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1NDP
 | | ADENOSINE 5'-DIPHOSPHATE BINDING AND THE ACTIVE SITE OF NUCLEOSIDE DIPHOSPHATE KINASE | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NUCLEOSIDE DIPHOSPHATE KINASE | | Authors: | Janin, J, Morera, S, Dumas, C, Lascu, I, Lebras, G, Veron, M. | | Deposit date: | 1993-11-29 | | Release date: | 1994-04-30 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase.
Biochemistry, 33, 1994
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4F7O
 | | Crystal structure of CSN5 | | Descriptor: | COP9 signalosome complex subunit 5, THIOCYANATE ION, ZINC ION | | Authors: | Echalier, A, Birol, M, Hoh, F, Dumas, C. | | Deposit date: | 2012-05-16 | | Release date: | 2013-01-23 | | Last modified: | 2013-02-06 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Insights into the regulation of the human COP9 signalosome catalytic subunit, CSN5/Jab1.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4GAF
 | | Crystal structure of EBI-005, a chimera of human IL-1beta and IL-1Ra, bound to human Interleukin-1 receptor type 1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, EBI-005, Interleukin-1 receptor type 1, ... | | Authors: | Hou, J, Townson, S.A, Kovalchin, J.T, Masci, A, Kiner, O, Shu, Y, King, B, Thomas, C, Garcia, K.C, Furfine, E.S, Barnes, T.M. | | Deposit date: | 2012-07-25 | | Release date: | 2013-02-20 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Design of a superior cytokine antagonist for topical ophthalmic use.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4NPN
 | | Crystal structure of human tetra-SUMO-2 | | Descriptor: | Small ubiquitin-related modifier 2 | | Authors: | Kung, C.C.-H, Naik, M.T, Chen, C.L, Ma, C, Huang, T.H. | | Deposit date: | 2013-11-22 | | Release date: | 2014-10-15 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.633 Å) | | Cite: | Structural analysis of poly-SUMO chain recognition by the RNF4-SIMs domain.
Biochem.J., 462, 2014
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3H0F
 | | Crystal structure of the human Fyn SH3 R96W mutant | | Descriptor: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, Proto-oncogene tyrosine-protein kinase Fyn | | Authors: | Ponchon, L, Hoh, F, Labesse, G, Dumas, C, Arold, S.T. | | Deposit date: | 2009-04-09 | | Release date: | 2010-04-21 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Synergy and allostery in ligand binding by HIV-1 Nef.
Biochem.J., 478, 2021
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1BU1
 | | SRC FAMILY KINASE HCK SH3 DOMAIN | | Descriptor: | PROTEIN (HEMOPOIETIC CELL KINASE) | | Authors: | Arold, S, Franken, P, Dumas, C. | | Deposit date: | 1998-09-09 | | Release date: | 1998-11-11 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
Biochemistry, 37, 1998
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4F0A
 | | Crystal structure of XWnt8 in complex with the cysteine-rich domain of Frizzled 8 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Frizzled-8, PALMITOLEIC ACID, ... | | Authors: | Janda, C.Y, Waghray, D, Levin, A.M, Thomas, C, Garcia, K.C. | | Deposit date: | 2012-05-03 | | Release date: | 2012-06-13 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | Structural basis of Wnt recognition by Frizzled.
Science, 337, 2012
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1ZXO
 | | X-ray Crystal Structure of Protein Q8A1P1 from Bacteroides thetaiotaomicron. Northeast Structural Genomics Consortium Target BtR25. | | Descriptor: | conserved hypothetical protein Q8A1P1 | | Authors: | Kuzin, A.P, Yong, W, Forouhar, F, Vorobiev, S, Xiao, R, Ma, C, Acton, T, Montelione, G.T, Hunt, J, Tong, L, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2005-06-08 | | Release date: | 2005-07-05 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | X-Ray structure of the hypothetical protein Q8A1P1 at the resolution 3.2A. Northeast Structural Genomics Consortium target BtR25.
To be Published
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