3H0F

Crystal structure of the human Fyn SH3 R96W mutant

Summary for 3H0F

• Entry DOI: 10.2210/pdb3h0f/pdb
• Related: 3H0H 3H0I
• Descriptor: Proto-oncogene tyrosine-protein kinase Fyn, 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE (3 entities in total)
• Functional Keywords: beta barrel, transferase
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: P06241
• Total number of polymer chains: 1
• Total formula weight: 8281.02

Authors

Ponchon, L.,Hoh, F.,Labesse, G.,Dumas, C.,Arold, S.T. (deposition date: 2009-04-09, release date: 2010-04-21, Last modification date: 2023-11-01)

• Primary citation: Aldehaiman, A.,Momin, A.A.,Restouin, A.,Wang, L.,Shi, X.,Aljedani, S.,Opi, S.,Lugari, A.,Shahul Hameed, U.F.,Ponchon, L.,Morelli, X.,Huang, M.,Dumas, C.,Collette, Y.,Arold, S.T.; Synergy and allostery in ligand binding by HIV-1 Nef.; Biochem.J., 478:1525-1545, 2021; PubMed: 33787846; DOI: 10.1042/BCJ20201002

Experimental method

X-RAY DIFFRACTION (2.61 Å)