7EM9
 
 | | Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I | | Descriptor: | Beta-2-microglobulin, Leucocyte antigen, SER-LEU-ASP-GLU-TYR-SER-SER-ASP-VAL | | Authors: | Yue, C, Xiang, W, Huang, X, Sun, Y, Xiao, J, Liu, K, Sun, Z, Qiao, P, Li, H, Gan, J, Ba, L, Chai, Y, Qi, J, Liu, P, Qi, P, Zhao, Y, Li, Y, Qiu, H.J, Gao, G.F, Gao, G, Liu, W.J. | | Deposit date: | 2021-04-13 | | Release date: | 2021-12-08 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Mooring Stone-Like Arg 114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major Histocompatibility Complex Class I.
J.Virol., 96, 2022
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7Y0W
 | | Local structure of BD55-5514 and BD55-5840 Fab and Omicron BA.1 RBD complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-5514H, BD55-5514L, ... | | Authors: | Zhang, Z, Xiao, J. | | Deposit date: | 2022-06-06 | | Release date: | 2022-09-28 | | Last modified: | 2023-04-12 | | Method: | ELECTRON MICROSCOPY (3.42 Å) | | Cite: | Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents.
Cell Rep, 41, 2022
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7Y0C
 | | Crystal structure of BD55-1403 and SARS-CoV-2 Omicron RBD | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, BD55-1403 Fab heavy chain, BD55-1403 Fab light chain, ... | | Authors: | Zhang, Z, Xiao, J. | | Deposit date: | 2022-06-04 | | Release date: | 2022-09-28 | | Last modified: | 2023-04-12 | | Method: | X-RAY DIFFRACTION (2.94 Å) | | Cite: | Rational identification of potent and broad sarbecovirus-neutralizing antibody cocktails from SARS convalescents.
Cell Rep, 41, 2022
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5ZRV
 | | Structure of human mitochondrial trifunctional protein, octamer | | Descriptor: | Trifunctional enzyme subunit alpha, mitochondrial, Trifunctional enzyme subunit beta | | Authors: | Liang, K, Li, N, Dai, J, Wang, X, Liu, P, Chen, X, Wang, C, Gao, N, Xiao, J. | | Deposit date: | 2018-04-25 | | Release date: | 2018-06-20 | | Last modified: | 2024-03-27 | | Method: | ELECTRON MICROSCOPY (7.7 Å) | | Cite: | Cryo-EM structure of human mitochondrial trifunctional protein
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4GY5
 | | Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3 | | Descriptor: | E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION | | Authors: | Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y. | | Deposit date: | 2012-09-05 | | Release date: | 2012-11-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.956 Å) | | Cite: | Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
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2CKA
 | | Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction | | Descriptor: | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 8 | | Authors: | Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E. | | Deposit date: | 2006-04-14 | | Release date: | 2007-05-08 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
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2CKC
 | | Solution structures of the BRK domains of the human Chromo Helicase Domain 7 and 8, reveals structural similarity with GYF domain suggesting a role in protein interaction | | Descriptor: | CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 7 | | Authors: | Ab, E, de Jong, R.N, Diercks, T, Xiaoyun, J, Daniels, M, Kaptein, R, Folkers, G.E. | | Deposit date: | 2006-04-14 | | Release date: | 2007-05-08 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structures of the Brk Domains of the Human Chromo Helicase Domain 7 and 8, Reveals Structural Similarity with Gyf Domain Suggesting a Role in Protein Interaction
To be Published
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1PGY
 | | Solution structure of the UBA domain in Saccharomyces cerevisiae protein, Swa2p | | Descriptor: | Swa2p | | Authors: | Chim, N, Gall, W.E, Xiao, J, Harris, M.P, Graham, T.R, Krezel, A.M. | | Deposit date: | 2003-05-28 | | Release date: | 2004-03-23 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Solution structure of the ubiquitin-binding domain in Swa2p from Saccharomyces cerevisiae.
PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
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6LX3
 | | Cryo-EM structure of human secretory immunoglobulin A | | Descriptor: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor | | Authors: | Wang, Y, Wang, G, Li, Y, Xiao, J. | | Deposit date: | 2020-02-10 | | Release date: | 2020-05-27 | | Last modified: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
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7Y0J
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7Y0H
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6LXW
 | | Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA | | Descriptor: | Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ... | | Authors: | Wang, Y, Wang, G, Li, Y, Xiao, J. | | Deposit date: | 2020-02-12 | | Release date: | 2020-05-27 | | Last modified: | 2020-07-22 | | Method: | ELECTRON MICROSCOPY (3.27 Å) | | Cite: | Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
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7YTE
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7YTD
 | | Cryo-EM structure of four human FcmR bound to IgM-Fc/J | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | | Authors: | Li, Y, Shen, H, Xiao, J. | | Deposit date: | 2022-08-14 | | Release date: | 2023-02-01 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
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7YTC
 | | Cryo-EM structure of human FcmR bound to IgM-Fc/J | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, Immunoglobulin J chain, ... | | Authors: | Li, Y, Shen, H, Xiao, J. | | Deposit date: | 2022-08-14 | | Release date: | 2023-02-01 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
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7YSG
 | | Cryo-EM structure of human FcmR bound to sIgM | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fas apoptotic inhibitory molecule 3, ... | | Authors: | Li, Y, Shen, H, Xiao, J. | | Deposit date: | 2022-08-12 | | Release date: | 2023-02-01 | | Last modified: | 2023-05-03 | | Method: | ELECTRON MICROSCOPY (3.18 Å) | | Cite: | Immunoglobulin M perception by Fc mu R.
Nature, 615, 2023
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7Y09
 | | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin J chain, ... | | Authors: | Shen, H, Ji, C, Xiao, J. | | Deposit date: | 2022-06-03 | | Release date: | 2023-03-29 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (3.71 Å) | | Cite: | Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
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7YG2
 | | Cryo-EM structure of human IgM-Fc in complex with the J chain and the DBL domain of DBLMSP2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DBLMSP2, ... | | Authors: | Shen, H, Ji, C, Xiao, J. | | Deposit date: | 2022-07-09 | | Release date: | 2023-03-29 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Plasmodium falciparum has evolved multiple mechanisms to hijack human immunoglobulin M.
Nat Commun, 14, 2023
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5X83
 | | Structure of DCC FN456 domains | | Descriptor: | Netrin receptor DCC | | Authors: | Finci, F.I, Xiao, J, Wang, J. | | Deposit date: | 2017-02-28 | | Release date: | 2017-09-06 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.997 Å) | | Cite: | Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC
Protein Cell, 8, 2017
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5XOO
 | | The structure of hydra Fam20 with sugar | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE, Glycosaminoglycan xylosylkinase, ... | | Authors: | Zhang, H, Xiao, J. | | Deposit date: | 2017-05-29 | | Release date: | 2018-04-11 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
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5YH3
 | | The structure of hFam20C and hFam20A complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Extracellular serine/threonine protein kinase FAM20C, Pseudokinase FAM20A | | Authors: | Zhu, Q, Xiao, J. | | Deposit date: | 2017-09-27 | | Release date: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (3.3 Å) | | Cite: | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
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5YH0
 | | The structure of DrFam20C1 | | Descriptor: | DrFam20C1 | | Authors: | Zhang, H, Xiao, J. | | Deposit date: | 2017-09-27 | | Release date: | 2018-04-11 | | Method: | X-RAY DIFFRACTION (3.45 Å) | | Cite: | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
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5YH2
 | | The structure of DrFam20C1 and hFam20A complex | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Family with sequence similarity 20, member Ca, ... | | Authors: | Zhang, H, Xiao, J. | | Deposit date: | 2017-09-27 | | Release date: | 2018-04-11 | | Last modified: | 2018-04-25 | | Method: | X-RAY DIFFRACTION (3.55 Å) | | Cite: | Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
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6G9I
 | | Crystal structure of Ebolavirus glycoprotein in complex with clomipramine | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE, Envelope glycoprotein,Envelope glycoprotein, ... | | Authors: | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | | Deposit date: | 2018-04-10 | | Release date: | 2018-05-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.19 Å) | | Cite: | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
J. Med. Chem., 61, 2018
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6G95
 | | Crystal structure of Ebolavirus glycoprotein in complex with thioridazine | | Descriptor: | 10-{2-[(2R)-1-methylpiperidin-2-yl]ethyl}-2-(methylsulfanyl)-10H-phenothiazine, 2-acetamido-2-deoxy-beta-D-glucopyranose, DIMETHYL SULFOXIDE, ... | | Authors: | Zhao, Y, Ren, J, Fry, E.E, Xiao, J, Townsend, A.R, Stuart, D.I. | | Deposit date: | 2018-04-10 | | Release date: | 2018-05-23 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structures of Ebola Virus Glycoprotein Complexes with Tricyclic Antidepressant and Antipsychotic Drugs.
J. Med. Chem., 61, 2018
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