4UM8
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![BU of 4um8 by Molmil](/molmil-images/mine/4um8) | Crystal structure of alpha V beta 6 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CACODYLATE ION, ... | Authors: | Dong, X, Springer, T.A. | Deposit date: | 2014-05-15 | Release date: | 2014-11-12 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.852 Å) | Cite: | Structural Determinants of Integrin Beta-Subunit Specificity for Latent Tgf-Beta Nat.Struct.Mol.Biol., 21, 2014
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6LPD
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![BU of 6lpd by Molmil](/molmil-images/mine/6lpd) | Phascolosoma esculenta | Descriptor: | FE (II) ION, FE (III) ION, Ferritin | Authors: | Su, X.R, Ming, T.H. | Deposit date: | 2020-01-09 | Release date: | 2021-01-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta. Febs Open Bio, 11, 2021
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6LPE
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![BU of 6lpe by Molmil](/molmil-images/mine/6lpe) | Phascolosoma esculenta ferritin | Descriptor: | Ferritin, MAGNESIUM ION, SULFATE ION | Authors: | Su, X.R, Ming, T.H. | Deposit date: | 2020-01-10 | Release date: | 2021-02-03 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | Structural comparison of two ferritins from the marine invertebrate Phascolosoma esculenta. Febs Open Bio, 11, 2021
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6MS9
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![BU of 6ms9 by Molmil](/molmil-images/mine/6ms9) | GDP-bound KRAS P34R mutant | Descriptor: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Bera, A.K, Westover, K.D. | Deposit date: | 2018-10-16 | Release date: | 2020-04-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R. Birth Defects Res, 112, 2020
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6O36
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![BU of 6o36 by Molmil](/molmil-images/mine/6o36) | |
6MTA
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![BU of 6mta by Molmil](/molmil-images/mine/6mta) | |
6O46
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![BU of 6o46 by Molmil](/molmil-images/mine/6o46) | |
6LP5
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![BU of 6lp5 by Molmil](/molmil-images/mine/6lp5) | Structure of Sinonovacula constricta ferritin | Descriptor: | FE (II) ION, FE (III) ION, Ferritin, ... | Authors: | Su, X.R, Ming, T.H, Su, C. | Deposit date: | 2020-01-08 | Release date: | 2020-04-08 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Crystallographic characterization of ferritin from Sinonovacula constricta. Biochem.Biophys.Res.Commun., 524, 2020
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7RP3
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![BU of 7rp3 by Molmil](/molmil-images/mine/7rp3) | Crystal structure of GNE-1952 alkylated KRAS G12C in complex with 2H11 CLAMP | Descriptor: | 1,2-ETHANEDIOL, 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, ... | Authors: | Oh, A, Tam, C, Wang, W. | Deposit date: | 2021-08-03 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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7RP2
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![BU of 7rp2 by Molmil](/molmil-images/mine/7rp2) | Crystal structure of Kas G12C in complex with 2H11 CLAMP | Descriptor: | 1,2-ETHANEDIOL, CACODYLATE ION, GTPase KRas, ... | Authors: | Oh, A, Tam, C, Wang, W. | Deposit date: | 2021-08-03 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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7RP4
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![BU of 7rp4 by Molmil](/molmil-images/mine/7rp4) | Crystal structure of KRAS G12C in complex with GNE-1952 | Descriptor: | 1-[4-[6-chloranyl-7-(5-methyl-1~{H}-indazol-4-yl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | Authors: | Oh, A, Tam, C, Wang, W. | Deposit date: | 2021-08-03 | Release date: | 2022-03-16 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Conformation-locking antibodies for the discovery and characterization of KRAS inhibitors. Nat.Biotechnol., 40, 2022
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5XPI
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![BU of 5xpi by Molmil](/molmil-images/mine/5xpi) | Structure of UHRF1 TTD in complex with NV01 | Descriptor: | E3 ubiquitin-protein ligase UHRF1, N-[3-(diethylamino)propyl]-2-(12-methyl-9-oxidanylidene-5-thia-1,10,11-triazatricyclo[6.4.0.0^2,6]dodeca-2(6),3,7,11-tetraen-10-yl)ethanamide | Authors: | Luo, X, Zhao, K. | Deposit date: | 2017-06-02 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Discovery of Small-Molecule Antagonists of the H3K9me3 Binding to UHRF1 Tandem Tudor Domain SLAS Discov, 23, 2018
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4YR8
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![BU of 4yr8 by Molmil](/molmil-images/mine/4yr8) | Crystal structure of JNK in complex with a regulator protein | Descriptor: | CHLORIDE ION, Dual specificity protein phosphatase 16, Mitogen-activated protein kinase 8 | Authors: | Liu, X, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2015-03-14 | Release date: | 2016-03-16 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A conserved motif in JNK/p38-specific MAPK phosphatases as a determinant for JNK1 recognition and inactivation. Nat Commun, 7, 2016
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5H19
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![BU of 5h19 by Molmil](/molmil-images/mine/5h19) | EED in complex with PRC2 allosteric inhibitor EED162 | Descriptor: | 5-(furan-2-ylmethylamino)-9-(phenylmethyl)-8,10-dihydro-7H-[1,2,4]triazolo[3,4-a][2,7]naphthyridine-6-carbonitrile, Histone-lysine N-methyltransferase EZH2, Polycomb protein EED | Authors: | Zhao, K, Zhao, M, Luo, X, Zhang, H. | Deposit date: | 2016-10-08 | Release date: | 2017-01-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Discovery and Molecular Basis of a Diverse Set of Polycomb Repressive Complex 2 Inhibitors Recognition by EED PLoS ONE, 12, 2017
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3GA3
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![BU of 3ga3 by Molmil](/molmil-images/mine/3ga3) | Crystal structure of the C-terminal domain of human MDA5 | Descriptor: | Interferon-induced helicase C domain-containing protein 1, MDA5, ZINC ION | Authors: | Li, P. | Deposit date: | 2009-02-16 | Release date: | 2009-02-24 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Crystal structure of the C-terminal domain of human MDA5 To be Published
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7LR3
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![BU of 7lr3 by Molmil](/molmil-images/mine/7lr3) | Complex of Fab 2/6.14 with domain 3 of P. berghei HAP2 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, D3_2/6.14 Fab heavy chain, D3_2/6.14 Fab light chain, ... | Authors: | Feng, J, Dong, X.C, Lu, C.F, Springer, T.A. | Deposit date: | 2021-02-15 | Release date: | 2021-12-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2. Elife, 10, 2021
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7LR4
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![BU of 7lr4 by Molmil](/molmil-images/mine/7lr4) | Complex of Fab 2/1.12 with domain 3 of P. berghei HAP2 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, D3_2/1.12 Fab heavy chain, D3_2/1.12 Fab light chain, ... | Authors: | Feng, J, Dong, X.C, Su, Y, Lu, X.F, Springer, T.A. | Deposit date: | 2021-02-15 | Release date: | 2021-12-15 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of malaria transmission blockade by a monoclonal antibody to gamete fusogen HAP2. Elife, 10, 2021
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6JPM
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![BU of 6jpm by Molmil](/molmil-images/mine/6jpm) | |
2WY4
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![BU of 2wy4 by Molmil](/molmil-images/mine/2wy4) | Structure of bacterial globin from Campylobacter jejuni at 1.35 A resolution | Descriptor: | CYANIDE ION, PROTOPORPHYRIN IX CONTAINING FE, SINGLE DOMAIN HAEMOGLOBIN | Authors: | Barynin, V.V, Sedelnikova, S.E, Shepherd, M, Wu, G, Poole, R.K, Rice, D.W. | Deposit date: | 2009-11-11 | Release date: | 2010-02-16 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The Single-Domain Globin from the Pathogenic Bacterium Campylobacter Jejuni: Novel D-Helix Conformation, Proximal Hydrogen Bonding that Influences Ligand Binding, and Peroxidase-Like Redox Properties. J.Biol.Chem., 285, 2010
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3GXB
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![BU of 3gxb by Molmil](/molmil-images/mine/3gxb) | Crystal structure of VWF A2 domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... | Authors: | Zhou, Y.F, Springer, T.A. | Deposit date: | 2009-04-02 | Release date: | 2009-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural specializations of A2, a force-sensing domain in the ultralarge vascular protein von Willebrand factor. Proc.Natl.Acad.Sci.USA, 106, 2009
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4ORA
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![BU of 4ora by Molmil](/molmil-images/mine/4ora) | Crystal structure of a human calcineurin mutant | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | Authors: | Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2014-02-11 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.747 Å) | Cite: | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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4ORB
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![BU of 4orb by Molmil](/molmil-images/mine/4orb) | Crystal structure of mouse calcineurin | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | Authors: | Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2014-02-11 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.108 Å) | Cite: | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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4ORC
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![BU of 4orc by Molmil](/molmil-images/mine/4orc) | Crystal structure of mammalian calcineurin | Descriptor: | CALCIUM ION, Calcineurin subunit B type 1, FE (III) ION, ... | Authors: | Ma, L, Li, S.J, Wang, J, Wu, J.W, Wang, Z.X. | Deposit date: | 2014-02-11 | Release date: | 2015-05-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Cooperative autoinhibition and multi-level activation mechanisms of calcineurin To be Published
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5JLB
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![BU of 5jlb by Molmil](/molmil-images/mine/5jlb) | |
5JJY
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![BU of 5jjy by Molmil](/molmil-images/mine/5jjy) | Crystal structure of SETD2 bound to histone H3.3 K36M peptide | Descriptor: | Histone H3.3, Histone-lysine N-methyltransferase SETD2, S-ADENOSYL-L-HOMOCYSTEINE, ... | Authors: | Yang, S, Zheng, X, Li, H. | Deposit date: | 2016-04-25 | Release date: | 2016-11-02 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.053 Å) | Cite: | Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase Genes Dev., 30, 2016
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