6MTA

KRAS P34R mutant structure in complex with GTP analogue

Summary for 6MTA

• Entry DOI: 10.2210/pdb6mta/pdb
• Descriptor: GTPase KRas, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: gtpase kras hydrolysis, hydrolase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 59635.02

Authors

Bera, A.K.,Westover, K.D. (deposition date: 2018-10-19, release date: 2020-04-15, Last modification date: 2023-10-11)

• Primary citation: Bera, A.K.,Lu, J.,Lu, C.,Li, L.,Gondi, S.,Yan, W.,Nelson, A.,Zhang, G.,Westover, K.D.; GTP hydrolysis is modulated by Arg34 in the RASopathy-associated KRASP34R.; Birth Defects Res, 112:708-717, 2020; PubMed: 32187889; DOI: 10.1002/bdr2.1647

Experimental method

X-RAY DIFFRACTION (2.15 Å)